Difference between pages "Alopecia - Hair Loss" and "OLED - Organic Light Emitting Diode"

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This report presents a brief introduction to OLED (organic light emitting diode) and technologies available for top emission OLED. A detailed taxonomy for OLED is presented covering parts of the type of OLED, material used, manufacturing, applications among others. A detailed landscape analysis of patent and non-patent literature is done with a focus on Top Emission OLED (TEOLED). The product information of major players in the market is also captured for OLED. The final section of the report covers the existing and future market predictions for OLED.
== Rationale ==
+
[[Image:OLED.png|right|thumb|800px| '''[http://electronics.howstuffworks.com/oled2.htm OLED Working Principle]]]
* "Medication for men plagued by hair loss has become a topic of interest in Japan since a drug company began marketing it at the end of last year." March 5th, 2006 – [http://stophair.setupmyblog.com/?p=55 Source]
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=Introduction=
* "An increasing number of companies are apparently turning the Chinese fear of a bald spot into big bucks with some doing so well they are branching out into other countries." February 16, 2006 – [http://stophair.setupmyblog.com/ Source]
+
*OLED technology was firstly developed in 1987 at Eastman Kodak Company by Tang and Van Slyke using small-molecule (sm-OLED). In 1990 Richard Friend, Jeremy Burroughes and Donal Bradley discovered electroluminescence capabilities from conjugated polymers so laying down the foundations for a new generation of flat panel displays.
"There is something in the air, or should we say in the hair, these days. Scientific research into hair loss remedies has never been more active or more exciting." June 7, 2006 - [http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=109&STORY=/www/story/06-07-2005/0003821470&EDATE= Source]
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*The growing number of electronic devices using organic light emitting diode displays shows that after years of promise, the technology is increasingly finding place in many products. But while OLED displays might challenge LCDs as the screens of choice for smaller gadgets, the technology may not become mainstream for notebook PCs or TVs within this decade.
 +
*OLED displays use organic compounds that emit light when exposed to an electric current. They are brighter, have better contrast, offer wider viewing angles, use less power, and provide faster response times than liquid crystal displays. OLED screens' thickness is a third of that of LCDs, since they don't need a back-light, and that makes them a good fit for portable electronics devices.
 +
==Read More? ==
 +
Click on [[OLED Background]] to read more about OLED.
  
==Contact Dolcera==
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Traditional light bulbs were invented more than 130 years ago. Since then the basic principle of creating light remains the same, although the design has been tweaked.An electric current passing through a tungsten wire causes it to heat up and glow white hot.Today, more than 20% of electricity used in US buildings is eaten up by lights and nearly half that amount is used by traditional, incandescent light bulbs. It has been a long-term goal of scientists to come up with something that would reduce this mammoth energy demand.
 +
 
 +
The OLEDs do not heat up like today's light bulbs and so are far more energy efficient and last longer.They also produce a light that is more akin to natural daylight than traditional bulbs. The new polymer uses a fluorescent blue material instead which lasts much longer and uses less energy.
 +
 
 +
=Top Emission OLED: Search Strategy=
 +
The present study on the IP activity in the area of OLED with focus on '''''Top Emission OLED (TEOLED)''''' is based on a search conducted on Micropat.
 +
 
 +
==Control Patents==
 +
{|border="2" cellspacing="0" cellpadding="4" width="100%"
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''S. No. '''</center>
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Patent/Publication No. '''</center>
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Publication Date(mm/dd/yyyy) '''</center>
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Assignee/Applicant '''</center>
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Title '''</center>
  
{| style="border:1px solid #AAA; background:#E9E9E9" align="center"
 
 
|-
 
|-
! style="background:lightgrey" | Contact Dolcera
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| style="background-color:#DCE6F1;padding:0.079cm;"| <center>1</center>
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| style="background-color:#DCE6F1;padding:0.079cm;"| <center>[http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=7791271.PN.&OS=PN/7791271&RS=PN/7791271 US7791271B2]</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>7/9/2010</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Global OLED Technology LLC
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Top-Emitting OLED Device With Light-Scattering Layer and Color-Conversion.
 +
 
 
|-
 
|-
! style="background:lightgrey" | Samir Raiyani
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| style="padding:0.079cm;"| <center>2</center>
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| style="padding:0.079cm;"| <center>[http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=7781961.PN.&OS=PN/7781961&RS=PN/7781961 US7781961B2]</center>
 +
| style="padding:0.079cm;"| <center>08/24/2010</center>
 +
| style="padding:0.079cm;"| Novaled AG
 +
| style="padding:0.079cm;"| Top Emitting, Electroluminescent Component With Frequency Conversion Centres.
 +
 
 
|-
 
|-
| '''Email''': [mailto:info@dolcera.com info@dolcera.com]
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| style="background-color:#DCE6F1;padding:0.079cm;"| <center>3</center>
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| style="background-color:#DCE6F1;padding:0.079cm;"| <center>[http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=7002293.PN.&OS=PN/7002293&RS=PN/7002293 US7002293B2]</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>02/21/2006</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Eastman Kodak Company
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Organic Light Emitting Diode With Improved Light Emission Through The Cathode.
 +
 
 
|-
 
|-
| '''Phone''': +1-650-269-7952
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| style="padding:0.079cm;"| <center>4</center>
|}
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| style="padding:0.079cm;"| <center>[http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6770502.PN.&OS=PN/6770502&RS=PN/6770502 US6770502B2]</center>
 +
| style="padding:0.079cm;"| <center>3/8/2004</center>
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Method Of Manufacturing a Top-emitting OLED display Device with Desiccant Structures.
  
== Introduction ==
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>5</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220080169757%22.PGNR.&OS=DN/20080169757&RS=DN/20080169757 US20080169757A1]</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>07/17/2008</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| TPO Displays Corp.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Top-Emitting Organic Electroluminescent Display
  
=== Hair basics ===
+
|-
* Hair is a complex and delicate part of the body.
+
| style="padding:0.079cm;"| <center>6</center>
* Keeping it healthy and beautiful is a challenge.
+
| style="padding:0.079cm;"| <center>[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060043373%22.PGNR.&OS=DN/20060043373&RS=DN/20060043373 US20060043373A1]</center>
* Hair grows everywhere on the body with the exception of lips, eyelids, palms of the hands and soles of the feet.
+
| style="padding:0.079cm;"| <center>2/3/2006</center>
* Hair is basically a form of skin.
+
| style="padding:0.079cm;"| Industrial Technology Research Institute
* Hair is made up of a protein called keratin.
+
| style="padding:0.079cm;"| Method for Manufacturing a Pixel Array of Top Emitting OLED.
* Each shaft of hair is made of two or three inter-twined layers of keratin which grow from a follicle beneath the skin.
+
* Hair Structure - [http://www.pg.com/science/haircare/hair_twh_12.htm Source]
+
* Hair Cycle - [http://www.follicle.com/hair-structure-life-cycle.html Source]
+
  
[[Image:Hairbasics.jpg|center|400px|Structure of Hair root and Hair bulb]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>7</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050236629%22.PGNR.&OS=DN/20050236629&RS=DN/20050236629 US20050236629A1]</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>10/27/2005</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Samsung Corp.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Top Emission Organic Light Emitting Diode Display Using Auxiliary Electrode to Prevent Voltage Drop of Upper Electrode and Method of Fabricating the Same.
  
=== What causes hair loss? ===    
+
|-
* Decrease in growth of hair
+
| style="padding:0.079cm;"| <center>8</center>
* Increase in shedding of hair
+
| style="padding:0.079cm;"| <center>[http://v3.espacenet.com/searchResults?NUM=EP1489671A2&DB=EPODOC&submitted=true&locale=en_V3&ST=number&compact=false EP1489671A2]</center>
* Breakage of hair
+
| style="padding:0.079cm;"| <center>12/22/2004</center>
* Conversion of thick terminal hairs to thin vellus hairs   
+
| style="padding:0.079cm;"| Global OLED Technology LLC
[[Image:Facts.jpg|thumb|right|250px|Survey results from Japan]]
+
| style="padding:0.079cm;"| Method of Making a Top-Emitting OLED device having Improved Power Distribution
Both men and women lose hair for similar reasons. Hair loss in men is often more dramatic, and follows a specific pattern of loss, one of which has been termed “Male Pattern Baldness" or "Androgenetic Alopecia".
+
  
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>9</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>[http://v3.espacenet.com/searchResults?NUM=EP1029336A1&DB=EPODOC&submitted=true&locale=en_V3&ST=number&compact=false EP1029336A1]</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>08/23/2000</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Fed Corp.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Top Emitting OLED with Refractory Metal Compounds as Bottom Cathode .
  
=== Types of alopecia===
+
|-
 +
| style="padding:0.079cm;"| <center>10</center>
 +
| style="padding:0.079cm;"| <center>[http://www.wipo.int/pctdb/en/wo.jsp?WO=2001057904 WO2001057904A1]</center>
 +
| style="padding:0.079cm;"| <center>9/8/2001</center>
 +
| style="padding:0.079cm;"| Emagin Corp.
 +
| style="padding:0.079cm;"| Low Absorption Sputter Protection Layer for OLED Structure.
  
* Alopecia Areata (AA): Hair loss occurring in patches anywhere on the body.
+
|}
* Alopecia Totalis (AT): Total loss of the hair on the scalp.
+
* Alopecia Universalis (AU): Total loss of all hair on the body.
+
* Alopecia Barbae: Loss of facial hair (for a man) especially in the beard area.
+
* Alopecia Mucinosa: A type of alopecia which results in scaley patches.
+
* Androgenetic Alopecia (AGA): Also known as male pattern baldness. It is a thinning of the hair to an almost transparent state, in both men or women. It is thought to be a hereditary form of hair loss.
+
* Traction Alopecia: Traction alopecia is usually due to excessive pulling or tension on hair shafts as a result of certain hair styles. It is seen more often in women, particularly those of East Indian and Afro-Caribbean origin. Hair loss depends on the way the hair is being pulled. Prolonged traction alopecia can stop new hair follicles from developing and leads to permanent hair loss.
+
* Anagen Effluvium: This hair loss is generally caused by chemicals such as those used to treat cancer. Initially it causes patchy hair loss, which often then leads to total hair loss. The good news is that when you stop using these chemicals the hair normally grows back (usually about 6 months later). Other drugs also can cause hair loss. Many medicines used to treat even common diseases can cause hair loss.
+
* Scarring Alopecia: A form of alopecia which leaves scarring on the area of hair loss.
+
* Telogen Effluvium: A form of hair loss where more than normal numbers of hair fall out. There is a general 'thinning' of the hair. Unlike some other hair and scalp conditions, it is temporary and the hair growth usually recovers. ([http://www.alopeciaonline.org.uk/about/types.asp Source])
+
  
=== Androgenetic alopecia ===
+
==Patent Classes==
* Gradual onset
+
* Transition from large, thick, pigmented terminal hairs to thinner, shorter, indeterminate hairs and finally to short, wispy, non-pigmented vellus hairs in the involved areas
+
* Characterized by a receding hairline and/or hair loss on the top of the head
+
  
'''Main causes'''
+
{|border="2" cellspacing="0" cellpadding="4" width="100%"
* Genetic predisposition
+
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''S. No.'''</center>
* Hormonal effect of androgen
+
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Class No.'''</center>
* Reduction of blood circulation around hair follicle
+
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Class Type'''</center>
* Deactivation of hair matrix cells
+
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Definition'''</center>
  
'''Some facts from Japan'''  
+
|-
 +
| style="padding:0.079cm;"| <center>1</center>
 +
| style="padding:0.079cm;"| [http://www.uspto.gov/web/patents/classification/uspc257/sched257.htm#C257S040000 257/40]
 +
| style="padding:0.079cm;"| USPC
 +
| style="padding:0.079cm;"| Active solid-state devices (e.g., transistors, solid-state diodes) /'''Organic semiconductor material '''
  
* Market size: ¥ 30 Billion
+
|-
* Number of products: more than 100
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>2</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://www.uspto.gov/web/patents/classification/uspc257/sched257.htm#C257SE51018 257/E51.018 ]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| USPC
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Active solid-state devices (e.g., transistors, solid-state diodes) / organic solid state devices, processes or apparatus peculiar to manufacture or treatment of such devices or of parts thereof / structural detail of device / '''light-emitting organic solid-state device with potential or surface barrier '''
  
(JICST-EPlus - Japanese Science & Technology)
+
|-
 +
| style="padding:0.079cm;"| <center>3</center>
 +
| style="padding:0.079cm;"| [http://www.uspto.gov/web/patents/classification/uspc257/sched257.htm#C257SE51019 257/E51.019 ]
 +
| style="padding:0.079cm;"| USPC
 +
| style="padding:0.079cm;"| Active solid-state devices (e.g., transistors, solid-state diodes) / organic solid state devices, processes or apparatus peculiar to manufacture or treatment of such devices or of parts thereof / structural detail of device / light-emitting organic solid-state device with potential or surface barrier / '''Electrode '''
  
== IP activity over the years ==
+
|-
The graph indicates:
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>4</center>
* Number of patents filed every 5 years (except for first 7 years).
+
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://www.uspto.gov/web/patents/classification/uspc257/sched257.htm#C257SE5102 257/E51.02 ]
* First solution proposed in 1973
+
| style="background-color:#DCE6F1;padding:0.079cm;"| USPC
* Filing trend indicates steep rise in activity recently.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Active solid-state devices (e.g., transistors, solid-state diodes) / organic solid state devices, processes or apparatus peculiar to manufacture or treatment of such devices or of parts thereof / structural detail of device / light-emitting organic solid-state device with potential or surface barrier / Electrode '''/ Encapsulation '''
[[Image:Year1.jpg|thumb|center|400px|IP Activity over years]]
+
  
== Major players ==
+
|-
[[Image:players.jpg|thumb|left|300px|Assignees with more than 20 patents ]]
+
| style="padding:0.079cm;"| <center>5</center>
[[Image:players1.jpg|thumb|center|300px|Assignees with fewer than 20 patents ]]<br>
+
| style="padding:0.079cm;"| [http://www.uspto.gov/web/patents/classification/uspc257/sched257.htm#C257SE51021 257/E51.021 ]
 +
| style="padding:0.079cm;"| USPC
 +
| style="padding:0.079cm;"| Active solid-state devices (e.g., transistors, solid-state diodes) / organic solid state devices, processes or apparatus peculiar to manufacture or treatment of such devices or of parts thereof / structural detail of device / light-emitting organic solid-state device with potential or surface barrier / Electrode '''/ Arrangements for extracting light from device (e.g., Bragg reflector pair) '''
  
* '''Active assignees'''
+
|-
Assignees currently active with more than 5 patents to their credit during 2000-2005.  
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>6</center>
* Warner with 9 patents,
+
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://www.uspto.gov/web/patents/classification/uspc257/sched257.htm#C257SE51018 257/E51.022 ]
* Bristol with 6 and
+
| style="background-color:#DCE6F1;padding:0.079cm;"| USPC
* Abbott with 5.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Active solid-state devices (e.g., transistors, solid-state diodes) / organic solid state devices, processes or apparatus peculiar to manufacture or treatment of such devices or of parts thereof / structural detail of device / light-emitting organic solid-state device with potential or surface barrier / '''Multicolor organic light-emitting device (OLED) '''
  
[[Image:Active.jpg|thumb|center|500px|Active Assignees]]
+
|-
 +
| style="padding:0.079cm;"| <center>7</center>
 +
| style="padding:0.079cm;"| [http://www.uspto.gov/web/patents/classification/uspc313/sched313.htm#C313S504000 313/504]
 +
| style="padding:0.079cm;"| USPC
 +
| colspan="12"  style="padding:0.079cm;"| Electric lamp and discharge devices/solid-state type/ with particular phosphor or electrode material / '''Organic phosphor '''
  
== Treatment Approaches==
+
|-
Composition of treatment for causes are identified and categorized as follows:
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>8</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://www.wipo.int/ipcpub/#refresh=page¬ion=scheme&version=20110101&symbol=H01L0027280000 H01L 27/28 ]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| IPC
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Semiconductor devices; electric solid state devices not otherwise provided for / devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate / '''including components using organic materials as the active part, or using a combination of organic materials with other materials as the active part'''
  
* Anti-androgens (Finasteride) [http://www.emedicine.com/DERM/topic21.htm source]
+
|-
* Vasodilators (Minoxidil) [http://www.emedicine.com/DERM/topic21.htm source]
+
| style="padding:0.079cm;"| <center>9</center>
* Double action (Anti-androgen + Vasodilator)
+
| style="padding:0.079cm;"| [http://www.wipo.int/ipcpub/#refresh=page¬ion=scheme&version=20110101&symbol=H01L0027320000 H01L 27/32 ]
* Hair matrix cells activator
+
| style="padding:0.079cm;"| IPC
 +
| style="padding:0.079cm;"| Semiconductor devices; electric solid state devices not otherwise provided for / devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate / including components using organic materials as the active part, or using a combination of organic materials with other materials as the active part / '''with components specially adapted for light emission, e.g. flat-panel displays using organic light-emitting diodes'''
  
{|border="1" cellpadding="2", style="#008080" align="center"
+
|-
|- style="font-weight:bold" valign="top"
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>10</center>
! Cause !! Treatment approach !! Pathways affected
+
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://www.wipo.int/ipcpub/#refresh=page¬ion=scheme&version=20110101&symbol=H01L0051500000 H01L 51/50 ]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| IPC
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Semiconductor devices; electric solid state devices not otherwise provided for / solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof / '''specially adapted for light emission, e.g. organic light emitting diodes (oled) or polymer light emitting devices (pled)'''
  
|-   valign="top"
+
|-
| Hormonal effect of androgen || Anti-androgens || Testosterone pathway
+
| style="padding:0.079cm;"| <center>11</center>
 +
| style="padding:0.079cm;"| [http://www.wipo.int/ipcpub/#refresh=page¬ion=scheme&version=20110101&symbol=H01L0051520000 H01L 51/52 ]
 +
| style="padding:0.079cm;"| IPC
 +
| style="padding:0.079cm;"| Semiconductor devices; electric solid state devices not otherwise provided for / solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof / '''Details of devices'''
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>12</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://www.wipo.int/ipcpub/#refresh=page¬ion=scheme&version=20110101&symbol=H01L0051560000 H01L ][http://www.wipo.int/ipcpub/#refresh=page¬ion=scheme&version=20110101&symbol=H01L0051560000 51/56 ]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| IPC
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Semiconductor devices; electric solid state devices not otherwise provided for/specially adapted for sensing infra-red radiation, light, electromagnetic radiation of shorter wavelength, or corpuscular radiation; specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation / '''Processes or apparatus specially adapted for the manufacture or treatment of such devices or of parts thereo'''
  
|-   valign="top"
+
|}
| Reduction of blood circulation around hair follicle || Vasodilators (eg. Minoxidil) || NO/cGMP Pathway
+
 
 +
==Concept Table==
 +
{|border="2" cellspacing="0" cellpadding="4" width="55%"
 +
| rowspan="2" align = "center" bgcolor = "#4F81BD" width="38"|<font color="#FFFFFF">'''S. No.'''</font>
 +
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Concept 1'''</font>
 +
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Concept 2'''</font>
 +
 
 +
|-
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Top emission'''</center>
 +
| colspan="3"  style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Organic Light Emitting Diode'''</center>
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>1</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| top emitting
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| oled
 +
|-
 +
| style="padding:0.079cm;"| <center>2</center>
 +
| style="padding:0.079cm;"| top emissive
 +
| colspan="2"  style="padding:0.079cm;"| polymer led
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>3</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| top emission
 +
| colspan="2"  style="background-color:#DCE6F1;padding:0.079cm;"| light emitting polymer diode
 +
|-
 +
| style="padding:0.079cm;"| <center>4</center>
 +
| style="padding:0.079cm;"| toled
 +
| colspan="2"  style="padding:0.079cm;"| organic led
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>5</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| teoled
 +
| colspan="2"  style="background-color:#DCE6F1;padding:0.079cm;"| organic electroluminescent diode
 +
|-
 +
| style="padding:0.079cm;"| <center>6</center>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| foled
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>7</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"|
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| sm-oled
 +
|-
 +
| style="padding:0.079cm;"| <center>8</center>
 +
| style="padding:0.079cm;"|
 +
| colspan="2"  style="padding:0.079cm;"| small molecule oled
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>9</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"|
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| amoled
 +
|-
 +
| style="padding:0.079cm;"| <center>10</center>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| pmoled
  
|-  valign="top"
 
| Deactivation of hair matrix cells || Hair matrix cells activator
 
|
 
* Wnt pathway
 
* STAT pathway
 
* TGF beta/BMP Pathway
 
* FGF Pathway
 
* MAPK Pathway
 
* NOTCH Pathway
 
* Hedgehog Pathway
 
 
|}
 
|}
 +
==Micropatent Search Strategy==
 +
'''Database:''' Micropat<br>
 +
'''Patent coverage:''' US, EP, WO, JP, DE, GB, FR<br>
 +
'''Time line:''' 1836/01/01 to 2011/02/20
 +
{|border="2" cellspacing="0" cellpadding="4" width="100%"
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''S. No.'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Concept'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Scope'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Search String'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''No. of Hits'''</center>
  
=== Anti-androgens ===
+
|-
* Anti-androgens are used in hormone therapy.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>1</center>
* Anti-androgens are designed to affect the hormones made in the adrenal glands. They don't stop the hormones from being made, but they stop them from having an effect leading to hair loss.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Classes - OLED
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Any Classification
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| H01L005150* OR H01L005152* OR H01L005156 OR H05B003308P OR 257E51.022
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 63152
  
'''What causes hair loss?'''
+
|-
* Testosterone is reduced to its active metabolite, Dihydrotestosterone (DHT) by the enzyme 5 alpha reductase.
+
| style="padding:0.079cm;"| <center>2</center>
* DHT attaches to androgen receptor sites at the hair follicle.  
+
| style="padding:0.079cm;"| Classes - Organic Semiconductor Devices
* DHT causes gradual miniaturization of the follicle, which eventually results in hair loss.
+
| style="padding:0.079cm;"| Any Classification
 +
| style="padding:0.079cm;"| 313504 OR 257040 OR 257E51.018 OR 257E51.019 OR 257E51.020 OR 257E51.021 OR H01L002728 OR H01L002732
 +
| style="padding:0.079cm;"| 27601
  
'''How do anti-androgens treat hair loss?'''
+
|-
* Anti-androgens compete with DHT to bind to the androgen receptor.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>3</center>
* Upon binding of anti-androgen in place of DHT, follicle miniaturization is lowered and hair loss prevented.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Top Emission keywords
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Claims, Title or Abstract
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| ((top emitting) OR (toled) OR (teoled) OR (te-oled) OR (top ADJ2 emitting) OR (top ADJ2 emissive) OR (top ADJ2 emission)) ADJ ((light ADJ emitting ADJ polymer) OR (organic ADJ electro-luminescence ADJ diode) OR (ORganic ADJ electroluminescent ADJ diode) OR (ploymer ADJ light ADJ emitting ADJ diode) OR (ORganic ADJ light ADJ emitting ADJ device) OR (self-luminous ADJ diode) OR (oled) OR (organic led arrays) OR (organic ADJ light ADJ emitting ADJ diode) OR (organic ADJ light ADJ emission ADJ diode) OR (polymer ADJ light ADJ emission ADJ device) OR (organic ADJ electroluminescent device) OR (oel) OR (oleds))
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 1141
  
==== Functions of Anti-androgen ====  
+
|-
[http://www.revivogen.com/revivogen/work.html Anti-androgen]
+
| style="padding:0.079cm;"| <center>4</center>
 +
| style="padding:0.079cm;"| OLED keywords
 +
| style="padding:0.079cm;"| Claims, Title or Abstract
 +
| style="padding:0.079cm;"| ((organic OR (small adj molecule*1) OR polymer*1) adj (lightemitting OR (light adj (emitting OR emission)) OR electroluminescen*2 OR (electro adj luminescen*2))) NEAR3 diode*1) OR oled*2 OR smled*2 OR pled*2 OR (light adj (emitting OR emission) adj polymer*1) OR ((organic OR (small adj molecule*1) OR polymer*1) NEAR3 led*2)
 +
| style="padding:0.079cm;"| 39392
  
[[Image:Andogen1.jpg|thumb|center|500px|Functions of Anti-androgen]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>5</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Top emissioin OLED keywords
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Claims, Title or Abstract
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| (((((organic OR (small ADJ molecule*1) OR polymer*1) ADJ (lightemitting OR (light ADJ (emitting OR emission)) OR electroluminescen*2 OR (electro ADJ luminescen*2))) NEAR3 diode*1) OR oled*2 OR smled*2 OR pled*2 OR (light ADJ (emitting OR emission) ADJ polymer*1) OR ((ORganic OR (small ADJ molecule*1) OR polymer*1) NEAR3 led*2)) AND ((top ADJ3 (emissi*2 OR emitting)))) OR (te ADJ oled*2)
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 429
  
==== IP Map for anti-androgen ====
+
|-
 +
| style="padding:0.079cm;"| <center>6</center>
 +
| style="padding:0.079cm;"| Top Emission keywords AND OLED classes
 +
| style="padding:0.079cm;"| Combined query
 +
| style="padding:0.079cm;"| 1 AND 3
 +
| style="padding:0.079cm;"| 809
  
{| border="1" cellpadding="0", style="#008080"
+
|-
!width="120" bgcolor=DodgerBlue|'''Pat/Pub#'''
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>7</center>
!width="100" bgcolor=DodgerBlue|'''Nature'''
+
| style="background-color:#DCE6F1;padding:0.079cm;"| LED Keywords
!width="450" bgcolor=DodgerBlue|'''Composition'''
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Claims, Title or Abstract
!width="400" bgcolor=DodgerBlue|'''Composition action'''
+
| style="background-color:#DCE6F1;padding:0.079cm;"| ((lightemitting OR (light ADJ (emitting OR emission)) OR electroluminescen*2 OR (electro ADJ luminescen*2)) NEAR3 diode*1) OR led*2 OR oled*2 OR smled*2 OR pled*2
|- style="height:20px"  
+
| style="background-color:#DCE6F1;padding:0.079cm;"| 1617014
|bgcolor=LightCyan|[[US20060009430]]
+
BLOTECH (2004)
+
|bgcolor=LightCyan|Natural extracts
+
|bgcolor=LightCyan|Palmetto berry extract (fatty acids & sterols), Pumpkin seed extract (Vitamins-B, alpha-linolenic acid, amino acids and phytosterols), Quercetin (Flavonoids) and Beta-sitosterol (Rice bran, wheat germ, corn oils and soybeans)
+
|bgcolor=LightCyan|Fatty acids – Inhibit testosterone
+
Sterols - Mechanism of action unknown.
+
+
Quercetin results in cell growth cycle.
+
  
Beta-sitosterol reduce inflammation on scalp
+
|-
|- style="height:20px"  
+
| style="padding:0.079cm;"| <center>8</center>
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060009427%22.PGNR.&OS=DN/20060009427&RS=DN/20060009427 US20060009427]
+
| style="padding:0.079cm;"| Top emission keywords AND Organic semiconductor devices classes AND Top emission keywords
WARNER LAMBERT(2004)
+
| style="padding:0.079cm;"| Combined query
|bgcolor=LightCyan|Organic compound
+
| style="padding:0.079cm;"| 2 AND 7 AND 3
|bgcolor=LightCyan|New class of 4-cycloalkoxy benzonitrile derivatives and salts
+
| style="padding:0.079cm;"| 224
|bgcolor=LightCyan|Acts as androgen receptor modulator and blocks formation of DHT.
+
|- style="height:20px"  
+
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050085467%22.PGNR.&OS=DN/20050085467&RS=DN/20050085467 US20050085467]
+
WARNER LAMBERT(2004)
+
|bgcolor=LightCyan|Organic compound
+
|bgcolor=LightCyan|New class of 6-sulfonamido-quinolin-2-one and 6-sulfonamido-2-oxo-chromene derivatives.
+
|bgcolor=LightCyan|The compounds inhibit, or decrease, activation of androgen receptor by androgens.
+
|- style="height:20px"  
+
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050118282%22.PGNR.&OS=DN/20050118282&RS=DN/20050118282 US20050118282]
+
APHIOS Corp (2003)
+
|bgcolor=LightCyan|Natural extracts
+
|bgcolor=LightCyan|Supercritical fluid isolate of Saw Palmetto and Sperol  (Serenoa repens berry) and their analogs or derivatives.
+
|bgcolor=LightCyan|Modulates androgenic activity by inhibiting 5.alpha.-reductase activity.
+
|- style="height:20px"
+
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060009429%22.PGNR.&OS=DN/20060009429&RS=DN/20060009429 US20060009429]
+
Fundacion Pablo Cassara (2003)
+
|bgcolor=LightCyan|Nucleotide
+
|bgcolor=LightCyan|Pharmacologically active oligonucleotides (encompass both DNA and S-DNA bond)
+
|bgcolor=LightCyan|Oligonucleotides inhibit androgen receptor (AR) expression at very low concentrations in skin and hair follicle
+
|- style="height:20px"
+
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220030007941%22.PGNR.&OS=DN/20030007941&RS=DN/20030007941 US20030007941]
+
PFIZER INC (2001)
+
|bgcolor=LightCyan|Organic compound
+
|bgcolor=LightCyan|Thyromimetic compounds (structurally similar to thyronine) with finasteride, or cyproterone acetate
+
|bgcolor=LightCyan|Activates thyroid hormone receptors in hair follicle which in turn promote elasticisation of follicle walls and hair follicle
+
|- style="height:20px"
+
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220030073616%22.PGNR.&OS=DN/20030073616&RS=DN/20030073616 US20030073616]
+
N/A (1995)
+
|bgcolor=LightCyan|Peptides/nucleic acid
+
|bgcolor=LightCyan|Bradykinin antagonist (peptide of plasma origin from kininogen precursor-kallikrein)
+
|bgcolor=LightCyan|Inhibits synthesis of bradykinin receptors or compounds by binding to B2 receptor
+
|- style="height:20px"
+
|bgcolor=LightCyan|[http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=EP0279010&F=0 EP0279010]
+
KAO Corp (1987)
+
|bgcolor=LightCyan|Natural extracts
+
|bgcolor=LightCyan|Walnut extract (leaves/pericarps) with an organic solvent
+
|bgcolor=LightCyan|Blocks formation of DHT
+
|}
+
  
=== Minoxidil (Vasodilators) ===
+
|-
* Minoxidil is a "potassium channel opener" that leads to vasodilation.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>9</center>
* The drug is available in two forms. Oral minoxidil is used to treat high blood pressure and the topical solution form is used to treat hair loss and baldness.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Top emissioin OLED keywords
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Full patent spec.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| (((((organic OR (small ADJ molecule*1) OR polymer*1) ADJ (lightemitting OR (light ADJ (emitting OR emission)) OR electroluminescen*2 OR (electro ADJ luminescen*2))) near3 diode*1) OR oled*2 OR smled*2 OR pled*2 OR (light ADJ (emitting OR emission) ADJ polymer*1) OR ((organic OR (small ADJ molecule*1) OR polymer*1) near3 LED*2)) near3 ((top ADJ3 (emissi*2 OR emitting)))) OR (te ADJ oled*2)
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 1506
  
'''What causes hair loss?'''
+
|-
* A thick network of tiny veins and arteries line the outer wall of the follicle. Blood pumps through the bulb and hair via this network.
+
| style="padding:0.079cm;"| <center>10</center>
* DHT accumulates in the hair follicles and roots, constricting the blood supply of oxygen and nutrients to the hair roots; which is also seen to possibly contribute towards hair loss.
+
| style="padding:0.079cm;"| German Keywords
 +
| style="padding:0.079cm;"| Full patent spec.
 +
| style="padding:0.079cm;"| ((top adj3 (emissi*2 OR emitting)) OR (Top NEAR2 emittierende*1)) NEAR3 ((organische NEAR2 (led*1 OR Leuchtdiode*1)) OR (Licht adj emittierende adj Polymer*1) OR oled*1)
 +
| style="padding:0.079cm;"| 1430
  
'''How does Minoxidil treat hair loss?'''
+
|-
* Minoxidil is applied to the scalp topically, where it dilates blood vessels in the scalp and sustains the hair follicles for longer period of time.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>11</center>
* Minoxidil is thought to have a direct mitogenic effect on epidermal cells, as has been observed both in vitro and in vivo. Though the mechanism of its action for causing cell proliferation is not very clear, minoxidil is thought to prevent intracellular calcium entry. Calcium normally enhances epidermal growth factors to inhibit hair growth, and Minoxidil by getting converted to minoxidil sulfate acts as a potassium channel agonist and enhances potassium ion permeability to prevent calcium ions from entering into cells. ([http://www.hairtransplantadvice.com/medical-hair-restoration.php Source])
+
| style="background-color:#DCE6F1;padding:0.079cm;"| French Keywords
* Minoxidil sulfate (MS) appears to be the active metabolite responsible for hair growth stimulation.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Full patent spec.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| ((top ADJ3 (émissive OR émettant)) OR (démission ADJ top) OR (top ADJ3 (emissi*2 OR emitting))) NEAR3 ((diode*1 NEAR3 électroluminescente NEAR3 organique*1) OR ((Polymère*1 OR organiques) ADJ2 led*1) OR (polymère*1 NEAR3 émettant NEAR3 lumière) OR oled*1)
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 1412
  
==== Functions of Vasodilators ====  
+
|-
 +
| style="padding:0.079cm;"| <center>12</center>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| Combined query
 +
| style="padding:0.079cm;"| 5 OR 6 OR 8 OR 9 OR 10 OR 11
 +
| style="padding:0.079cm;"| 2113 ('''1132''' unique)
  
[[Image:minoxidil1.jpg|thumb|center|500px|Functions of Monoxidil [http://www.nurseminerva.co.uk/diagrams.htm#Diagram%201 source]]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>13</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Control Patents
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Patent/Publication No.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| WO2001057904A1 OR EP1029336A1 OR EP1489671A2 OR US20050236629A1 OR US20060043373A1 OR US20080169757A1 OR US6770502B2 OR US7002293B2 OR US7781961B2 OR US7791271B2
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 10
  
==== IP Map for Vasodilators ====
+
|-
 +
| style="padding:0.079cm;"| <center>14</center>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| Combined query
 +
| style="padding:0.079cm;"| 12 AND 13
 +
| style="padding:0.079cm;"| 10
  
{| border="1" cellpadding="2"
 
!width="120" bgcolor=DodgerBlue|'''Pat/Pub#'''
 
!width="75" bgcolor=DodgerBlue|'''Nature'''
 
!width="600" bgcolor=DodgerBlue|'''Composition'''
 
!width="300" bgcolor=DodgerBlue|'''Composition action'''
 
|- style="height:100px"
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220040157856%22.PGNR.&OS=DN/20040157856&RS=DN/20040157856 US20040157856]
 
WARNER LAMBERT(2002)
 
|bgcolor=LightCyan|Organic compound
 
|bgcolor=LightCyan|Benzopyran compounds
 
|bgcolor=LightCyan|Rapidly metabolizes, and causes reduced cardiovascular effects as compared to other known potassium channel openers
 
|- style="height:100px"
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050053572%22.PGNR.&OS=DN/20050053572&RS=DN/20050053572 US20050053572]
 
LG HOUSEHOLD & HEALTH CARE(2001)
 
|bgcolor=LightCyan|Natural extracts
 
|bgcolor=LightCyan|Sophora flavescens extract (alkaloids & flavonoids, luteolin-7-glucose and cytosine) Hinokitiol (Taiwan hinoki oil, Aomori, Western Red Cedar oil) and Nicotinamide (Vitamin B complex)
 
|bgcolor=LightCyan|Promotes function of cell activity and dilates blood vessels
 
 
|}
 
|}
 +
==Scientific Literature Search==
 +
{|border="2" cellspacing="0" cellpadding="4" width="100%"
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''S.No'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Database'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Query'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Limits by Date'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''No.Of Hit'''</center>
  
=== Double action (Anti-androgen + Vasodilator) ===
+
|-
* Combination of Vasodilator + Anti-androgen (double action) composition for effective treatment of Male-Pattern Baldness.
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''1'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Google scholar
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| (Top emitting or top emission or top emissive) and ((organic light emitting diode) or (polymer led) or (light emitting polymer led) or (OLED))
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 1990-2011
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 1840
  
'''What is the problem with using only Anti-androgen therapy?'''
+
|}
* Anti-androgen is not effective in addressing the issue of vasocontriction around hair follicles due to sebum oil build up.
+
* Anti-androgen only prevents binding of DHT to androgen receptors. However, the effects of improper oxygen and nutrient supply to the brain due to vasocontriction still remains and gradually causes hair loss.
+
  
'''What is the problem with using only Vasodilator (or Minoxidil only) therapy?'''
+
==Search in Japanese database==
* Vasodilator or Minoxidil-based products are generally not effective in stopping hair loss as vasodilators (or Minoxidil) do not block the harmful effects of DHT in the scalp and hair follicles.
+
* Vasodilators or Minoxidil simply dilate blood vessels in the scalp. However, the harmful DHT  still gets produced in the body, enters the scalp and hair follicles causing hair loss.
+
  
'''How is the combination of Anti-androgens and Vasodilator (or Minoxidil) effective?'''
+
Database: IPDL (Industrial property digital library), Japan
* Anti-androgens target the problem of DHT binding to androgen receptors and prevents follicle miniaturization.
+
* Vasodilators like Minoxidil cause vasodilation and therefore improve supply of oxygen and nutrients to the hair follicle and roots.
+
* Combination therapy therefore proves to be much more effective than individual therapy.
+
  
==== Functions of (Anti-androgen + Vasodilators) ====  
+
Date of search: 1900/01/01 to 2011/02/15
[http://www.revivogen.com/revivogen/work.html Anti-androgen ]and [http://www.xandrox.net/articles/article01.htm Minoxidil]
+
 
[[Image:Doubleaction1.jpg|thumb|center|500px|Functions of (Anti-androgen + Vasodilators)]]
+
{|border="2" cellspacing="0" cellpadding="4" width="50%"
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''S.No.'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Issue/Publication date'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''F-Term Theme'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''FI/F-term/Facet'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Hits'''</center>
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''1'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 1900/01/01 to 2011/03/02
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 3K107
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| DD03*[AA01+BB01+BB02+BB03+BB04+BB05+BB06+BB07+BB08+DD01+DD04+DD42+DD50+CC01+CC02+CC04+CC06+CC07+ <br>CC08+CC09+EE02+EE03+EE06+EE22+GG01+GG02+GG03+GG04+GG05+GG06+GG07+GG08+GG08]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''1596'''
  
==== IP Map for (Anti-androgen + Vasodilators) ====
 
{| border="1" cellpadding="3"
 
!width="120" bgcolor=DodgerBlue|'''Pat/Pub#'''
 
!width="75" bgcolor=DodgerBlue|'''Nature'''
 
!width="500" bgcolor=DodgerBlue|'''Composition'''
 
!width="500" bgcolor=DodgerBlue|'''Composition action'''
 
|- style="height:100px"
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060052405%22.PGNR.&OS=DN/20060052405&RS=DN/20060052405 US20060052405]
 
N/A(2000)
 
|bgcolor=LightCyan|Peptides
 
|bgcolor=LightCyan|Testosterone blocker or vascular toner (Flutamide, cyproterone acetate, spironolactone, progesterone, or analogs or derivatives) and minoxidil mixed along with non-retinoid penetration enhancer and sunscreen
 
|bgcolor=LightCyan|Inhibits 5.alpha.-reductase activity (block DHT) and increase blood flow on the scalp
 
|- style="height:100px"
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050123577%22.PGNR.&OS=DN/20050123577&RS=DN/20050123577 US20050123577]
 
L'OREAL(2000)
 
|bgcolor=LightCyan|Peptides
 
|bgcolor=LightCyan|Prostaglandin (polyunsaturated fatty acids) EP-2, EP-3 EP-4 receptor agonist with Minoxidil, 2,4-diaminopyrimidine 3-oxide, and Aminexil, cyclic AMP
 
|bgcolor=LightCyan|Minoxidil (designed to mimic nitric oxide's effects) grows hair via prostaglandin-H synthase stimulation. EP-3 and EP-4 are expressed in anagen hair follicles which induce a reduction in the level of cAMP
 
|- style="height:100px"
 
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6447762.PN.&OS=PN/6447762&RS=PN/6447762 US6447762]
 
COLOMER GROUP(1999)
 
|bgcolor=LightCyan|Natural extract
 
|bgcolor=LightCyan|Hop extract (oil contains terpenes and humulene), Rosemary extract (hydroalcohol), Swertia extract (glycol with a swertiamarin), Silanodiol salicylate (biologically active silicon compound)
 
|bgcolor=LightCyan|Inhibits activity of 5-alpha-reductase, protects follicular cell membranes by neutralizing action of oxidation reaction in tissues, stimulates hair follicles and blood circulation to the hair root, supplies oxygen and nutrients to base of follicle, retains humidity, avoids dehydration of scalp
 
 
|}
 
|}
  
=== Hair matrix cell activator ===
+
*F-Terms and theme used in search
Hair matrix cell activator is a substance that acts at the matrix cells in the hair follicle preventing their degradation.
+
{|border="2" cellspacing="0" cellpadding="4" width="50%"
 +
| colspan="3"  style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Japanese F-term search'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Definition'''</center>
  
'''What causes hair loss?'''
+
|-
* Stem cells are interspersed within the basal layer of the outer root sheath and in an area called the bulge.
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Sr. No.'''</center>
* Stem cells migrate to hair matrix where they start to divide and differentiate, under the influence of substances produced by cells of the dermal papilla.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term theme'''
* Perifollicular matrix cells undergo slow degradation which prevents follicle stimulation.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| 3K107
* Hair follicle activation is required for hair growth and thus inhibition of follicle activation eventually leads to hair loss.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Electroluminescent light sources
  
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>1</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| AA01
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Organic electroluminescent element.
  
'''How does hair cell matrix activator treat hair loss?'''
+
|-
* Hair cell matrix activator slows down and inhibits degradation of the perifollicular matrix.
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>2</center>
* This leads to an increase in hair follicle matrix cells that differentiate from progenitor stem cells.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
* Matrix activator allows activation of hair matrix cells and therefore follicle stimulation leading to hair growth.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| BB01
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Used in displays.
  
==== Functions of Hair matrix cell activator ====
+
|-
[http://www.ijdb.ehu.es/fullaccess/fulltext.04023/ft163.pdf Hair matrix cell activator]
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>3</center>
[[Image:Hair matrix.jpg|thumb|center|500px|Functions of Hair matrix cell activator ]]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| BB02
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Used in Lights or light sources
  
==== IP Map for Hair matrix cell activator ====
+
|-
{| border="1" cellpadding="2"
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>4</center>
!width="120" bgcolor=DodgerBlue|'''Pat/Pub#'''
+
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
!width="100" bgcolor=DodgerBlue|'''Nature'''
+
| style="background-color:#DCE6F1;padding:0.079cm;"| BB03
!width="200" bgcolor=DodgerBlue|'''Composition'''  
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Used in Backlights or the like for liquid crystals
!width="600" bgcolor=DodgerBlue|'''Composition action'''
+
|- style="height:50px"
+
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220020052498%22.PGNR.&OS=DN/20020052498&RS=DN/20020052498 US20020052498]
+
SHISEIDO(1999)
+
|bgcolor=LightCyan|Organic compound
+
|bgcolor=LightCyan|(2-substituted oxyphenyl) alkanamide derivative and its salt
+
|bgcolor=LightCyan|Mechanism of action has not been made clear, having excellent hair follicle activating action and regrowth promoting effect
+
|- style="height:50px"
+
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220040071647%22.PGNR.&OS=DN/20040071647&RS=DN/20040071647 US20040071647]
+
L'OREAL(1998)
+
|bgcolor=LightCyan|Peptides
+
|bgcolor=LightCyan|Metalloprotease (MMP-9) inhibitor (thiol or a hydroxamate) other than chelating calcium ions
+
|bgcolor=LightCyan|Reducing the expression of MMPs (Metalloproteases) in the scalp - slows down or inhibits the degradation of the perifollicular matrix (extracellular matrix surrounding the hair follicle)
+
|}
+
  
== Technology mapping based on patents analyzed ==
+
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>5</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| BB04
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Used in printer heads
  
=== IPMap: Composition nature matrix ===
+
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>6</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| BB05
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Used in lasers
  
{| border="1" cellpadding="11", style="#008080"
 
!width="120" bgcolor=DodgerBlue|'''Year'''
 
!width="200" bgcolor=DodgerBlue|'''Organic Compound'''
 
!width="200" bgcolor=DodgerBlue|'''Natural extracts'''
 
!width="200" bgcolor=DodgerBlue|'''Peptides'''
 
!width="200" bgcolor=DodgerBlue|'''Nucleotides'''
 
!width="200" bgcolor=DodgerBlue|'''Natural extract + Organic comp'''
 
|- style="height:10px"
 
|bgcolor=LightCyan|2005
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|UNILEVER (1)
 
|-
 
|bgcolor=LightCyan|2004
 
|bgcolor=LightCyan|WARNER (1)
 
|bgcolor=LightCyan|BLOTECH (1)
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|KAO (1)
 
|-
 
|bgcolor=LightCyan|2003
 
|bgcolor=LightCyan|WARNER (1)
 
|bgcolor=LightCyan|APHIOS (1)
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|FUNDACION (1)
 
|bgcolor=LightCyan|....
 
|-
 
|bgcolor=LightCyan|2002
 
|bgcolor=LightCyan|WARNER (1)
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|-
 
|bgcolor=LightCyan|2001
 
|bgcolor=LightCyan |PFIZER  (1)
 
|bgcolor=LightCyan|LG HEALTH-CARE (1)
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|-
 
|bgcolor=LightCyan|2000
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|L’OREAL (1) / N/A (1)
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|-
 
|bgcolor=LightCyan|1999
 
|bgcolor=LightCyan|SHISEDIO (1)
 
|bgcolor=LightCyan|COLOMER (1)
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|-
 
|bgcolor=LightCyan|1998
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|L’OREAL (1)
 
|bgcolor=LightCyan|....
 
|bgcolor=LightCyan|....
 
 
|-
 
|-
|bgcolor=LightCyan|1995
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>7</center>
|bgcolor=LightCyan|....
+
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
|bgcolor=LightCyan|....
+
| style="background-color:#DCE6F1;padding:0.079cm;"| BB06
|bgcolor=LightCyan|N/A (1)
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Used in designs or advertisements
|bgcolor=LightCyan|....
+
 
|bgcolor=LightCyan|....
+
 
|-
 
|-
|bgcolor=LightCyan|1987
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>8</center>
|bgcolor=LightCyan|....
+
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
|bgcolor=LightCyan|KAO (1)
+
| style="background-color:#DCE6F1;padding:0.079cm;"| BB07
|bgcolor=LightCyan|....
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Used in timepieces
|bgcolor=LightCyan|....
+
 
|bgcolor=LightCyan|....
+
 
|-
 
|-
|bgcolor=LightCyan|1982
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>9</center>
|bgcolor=LightCyan|UNILEVER (1)
+
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
|bgcolor=LightCyan|....
+
| style="background-color:#DCE6F1;padding:0.079cm;"| BB08
|bgcolor=LightCyan|....
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Used in on-board use
|bgcolor=LightCyan|....
+
 
|bgcolor=LightCyan|....
+
|-
|}
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>10</center>
=== Focus of patents ===
+
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| DD01
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Having feature of all direction of light emission.
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>11</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| DD03
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Having top emission.
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>12</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| DD04
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Having double sided emission.
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>13</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| DD42
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Having Organic materials.
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>14</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| DD50
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Structured with Light emitting layers
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>15</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| CC01
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Having Light emitting layers
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>16</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| CC02
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Light emission characteristics were improved.
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>17</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| CC04
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Has an effect on brightness.
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>18</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| CC06
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Has an effect on efficiency
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>19</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| CC07
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Has an effect on colours.
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>20</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| CC08
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Has an effect on Colour purity; Colour temperatures; Light emission wavelengths, including UV
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>21</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| CC09
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Has colour balance feature
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>22</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| EE02
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Has white light emission.
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>23</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| EE03
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Display having Passive matrices
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>24</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| EE06
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Display having Active matrices
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>25</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| EE22
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Display having with RGB picture elements having different areas
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>26</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| GG01
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Dispaly having color filters.
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>27</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| GG02
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Apparatus for deposition
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>28</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| GG03
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Apparatus for dry methods
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>29</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| GG04
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Apparatus for chemical vapour deposition
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>30</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| GG05
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Apparatus for evaporation
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>31</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| GG06
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Apparatus for sputtering
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>32</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| GG07
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Apparatus for wet methods
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>33</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| GG08
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Apparatus for printing
 +
 
 +
|-
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>34</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''F- Term'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| GG08
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Apparatus for Inkjet
  
{| border="1" cellpadding="17", style="#008080"
 
!width="800" bgcolor=DodgerBlue|'''Focus of patents'''
 
!width="150" bgcolor=DodgerBlue|'''Patent no.'''
 
!width="100" bgcolor=DodgerBlue|'''Rec. no.'''
 
|- 
 
|bgcolor=LightCyan|2-substituted oxyphenyl alkanamide derivative having excellent hair growth effect.
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220020052498%22.PGNR.&OS=DN/20020052498&RS=DN/20020052498 US20020052498]
 
|bgcolor=LightCyan|1
 
|- 
 
|bgcolor=LightCyan|Thyromimetic compounds, and its role in treating hair loss
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220030007941%22.PGNR.&OS=DN/20030007941&RS=DN/20030007941 US20030007941]
 
|bgcolor=LightCyan|2
 
|- 
 
|bgcolor=LightCyan|Saw Palmetto berry extract, pumpkin seed extract, sitosterol and quercetin for the treatment and prevention of the biologically detrimental effects of DHT
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060009430%22.PGNR.&OS=DN/20060009430&RS=DN/20060009430 US20060009430]
 
|bgcolor=LightCyan|3
 
|- 
 
|bgcolor=LightCyan|4-cycloalkoxy benzonitriles and its use as androgen receptor modulators
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060009427%22.PGNR.&OS=DN/20060009427&RS=DN/20060009427 US20060009427]
 
|bgcolor=LightCyan|4
 
|-
 
|bgcolor=LightCyan|Supercritical fluid isolate of Saw Palmetto, Sperol for inhibition of 5-.alpha.-reductase activity
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050118282%22.PGNR.&OS=DN/20050118282&RS=DN/20050118282 US20050118282]
 
|bgcolor=LightCyan|5
 
|- 
 
|bgcolor=LightCyan|New class of quinolin-2-ones and chromen-2-ones andtheir use as androgen receptor antagonists
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050085467%22.PGNR.&OS=DN/20050085467&RS=DN/20050085467 US20050085467]
 
|bgcolor=LightCyan|6
 
|- 
 
|bgcolor=LightCyan|Antiandrogen oligonucleotides usable for the treatment of dermatological androgen-related disorders
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060009429%22.PGNR.&OS=DN/20060009429&RS=DN/20060009429 US20060009429]
 
|bgcolor=LightCyan|7
 
|- 
 
|bgcolor=LightCyan|Bradykinin antagonists for stimulating or inducing hair growth and/or arresting hair loss
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220030073616%22.PGNR.&OS=DN/20030073616&RS=DN/20030073616 US20030073616]
 
|bgcolor=LightCyan|8
 
|- 
 
|bgcolor=LightCyan|Extract from walnut leaves and/or pericarps as 5 alpha -reductase inhibitor
 
|bgcolor=LightCyan|[http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=EP0279010&F=0 EP0279010]
 
|bgcolor=LightCyan|9
 
|- 
 
|bgcolor=LightCyan|Stimulating hair growth using benzopyrans
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220040157856%22.PGNR.&OS=DN/20040157856&RS=DN/20040157856 US20040157856]
 
|bgcolor=LightCyan|10
 
|- 
 
|bgcolor=LightCyan|Sophora flavescens extract, Coicis semen extract, clove extract, etc for promoting hair growth, function of cell activity and dilating peripheral blood vessels.
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050053572%22.PGNR.&OS=DN/20050053572&RS=DN/20050053572 US20050053572]
 
|bgcolor=LightCyan|11
 
|- 
 
|bgcolor=LightCyan|Compositions to prevent or reduce hair loss
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060052405%22.PGNR.&OS=DN/20060052405&RS=DN/20060052405 US20060052405]
 
|bgcolor=LightCyan|12
 
|- 
 
|bgcolor=LightCyan|Prostaglandin EP-3 receptor antagonists for reducing hair loss
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050123577%22.PGNR.&OS=DN/20050123577&RS=DN/20050123577 US20050123577]
 
|bgcolor=LightCyan|13
 
|- 
 
|bgcolor=LightCyan|Synergic effect arising from the interaction of active ingredients, consisting of three plant extracts and a synthetic organosilicic compound for prevent hair loss and stimulate hair growth
 
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6447762.PN.&OS=PN/6447762&RS=PN/6447762 US6447762]
 
|bgcolor=LightCyan|14
 
|- 
 
|bgcolor=LightCyan|Metalloprotease inhibitors to induce and/or stimulate the growth
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220040071647%22.PGNR.&OS=DN/20040071647&RS=DN/20040071647 US20040071647]
 
|bgcolor=LightCyan|15
 
|- 
 
|bgcolor=LightCyan|Method of decreasing sebum production and pore size
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050277699%22.PGNR.&OS=DN/20050277699&RS=DN/20050277699 US20050277699 ]
 
|bgcolor=LightCyan|16
 
|- 
 
|bgcolor=LightCyan|Method for reducing sebum on the hair and skin
 
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=4529587.PN.&OS=PN/4529587&RS=PN/4529587 US4529587]
 
|bgcolor=LightCyan|17
 
 
|}
 
|}
  
=== Technology focus===
+
=Taxonomy=
[[Image:Technologyfocus2.jpg|thumb|center|700px|Technology focus]]
+
<mm>[[OLED Taxonomy.mm]]</mm>
=== Distribution of patents ===
+
+
==== By patent types ====
+
[[Image:Didtribution.jpg|thumb|center|700px|Distribution based on patent types ]]
+
  
 +
=Sample Analysis=
 +
==Patent Analysis==
 +
A sample of 200 patents from the search is analyzed based on the taxonomy. Provided a link below for sample spread sheet analysis for Top Emission OLED.
  
==== By key ingredients ====
+
{|border="2" cellspacing="0" cellpadding="4" width="100%"
[[Image:key1.jpg|thumb|center|700px|Distribution of key ingredients]]
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''S.No'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Patent/Publication No.'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Date of Publication'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Assignee / Applicant'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Title'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Problem'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Solution'''</center>
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''1'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>US7692191B2</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>04/06/2010</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Samsung Mobile Display Co., Ltd.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Top-emitting organic light emitting device
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| In the conventional top-emitting organic light emitting device, each pixel electrode is designed to have a minimum width, and neighboring pixel electrodes are designed to be widely spaced apart from each other by as much as 17 .mu.m. Therefore, the wide space between the pixel electrodes leaks emitted light, thereby deteriorating the voltage-current characteristics of the thin film transistors i.e., increasing photo-leakage.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| In this patent the top-emitting organic light emitting device has maximized the width of a pixel electrode , thereby enhancing aperture ratio. Furthermore, the pixel electrode is arranged to overlap all thin film transistors, so that light is prevented from leaking through a space between neighboring pixel electrodes, thereby reducing photo-leakage of the thin film transistor.
  
==== By target disease ====
+
|-
[[Image:target.jpg|thumb|center|700px|Distribution based on target diseases]]
+
| style="padding:0.079cm;"| <center>'''2'''</center>
 +
| style="padding:0.079cm;"| <center>US7554259B2</center>
 +
| style="padding:0.079cm;"| <center>06/30/2009</center>
 +
| style="padding:0.079cm;"| Sanyo Electric Co., Ltd.
 +
| style="padding:0.079cm;"| Light emitting display apparatus having excellent color reproducibility
 +
| style="padding:0.079cm;"| Organic electroluminescence panel obtains white light by synthesizing two lights each having complementary color to the other, and the three primary colors differ in luminous intensity. Therefore it is difficult to set chromaticity of white light to desired level. And even after color-filter transmission, red light and blue light will have stronger luminous intensity than green light.
 +
| style="padding:0.079cm;"| The present invention objective provide a light emitting display apparatus having excellent color reproducibility. Organic light emitting layer that synthesizes two or more complementary colors of light that are complementary to each other thereby producing white light. It has a resonant structure by which a resonant wavelength is set to a predetermined wavelength, and outputs the white light via the resonant structure where the predetermined wavelength substantially coincides with a wavelength corresponding to a primary color whose luminous intensity is uniform.With the stated construction, non-uniformity in luminous intensity among three primary colors is alleviated by means of amplified luminous intensity due to resonance. This will help obtain white light in which the primary colors are balanced well.
  
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''3'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>US7332859B2</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>02/19/2008</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Canon Kabushiki Kaisha
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Organic luminescence device with anti-reflection layer and organic luminescence device package
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| In organic luminescence device, the transparent electrode is formed by a material of a refractive index higher than that of air or nitrogen, constituting the external environment of the organic luminescence device. Therefore, the light emitted from the light emitting layer is reflected at a light emitting surface of the transparent electrode , namely at the interface between the transparent electrode and the air constituting the external environment in FIG. 1. For this reason, such organic luminescence device has been associated with a low efficiency of light emission to the exterior.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| The present invention is to provide an organic luminescence device of a high light-emitting efficiency to the exterior and an organic luminescence device of a satisfactory contrast. A case holding the organic luminescence device in an internal holding space, in which a light emitted from the organic luminescence device, is emitted to the exterior through a light emitting side of the case; wherein anti-reflection means is provided on a light-emitting face on the light-emitting side among faces constituting the internal holding space of the case
 +
| colspan="7"  style="padding:0.079cm;"|
  
==== Key ingredients vs. Target disease ====
+
|-
[[Image:key&target1.jpg|thumb|center|1000px|Key ingredients vs. Target disease]]
+
| style="padding:0.079cm;"| <center>'''4'''</center>
 +
| style="padding:0.079cm;"| <center>US6885157B1</center>
 +
| style="padding:0.079cm;"| <center>04/26/2005</center>
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Integrated touch screen and OLED flat-panel display
 +
| style="padding:0.079cm;"| It has the problem of multiple external electrical connections by employing a flat-panel display having a substrate that extends beyond the substrate of the resistive touch screen.
 +
| style="padding:0.079cm;"| The present invention has the advantage that it reduces the costs and improves the reliability and performance of a touch screen that is used with an OLED flat-panel display by integrating cable connections on a single substrate and providing touch screen signal processing on the display substrate.
 +
| colspan="7"  style="padding:0.079cm;"|
  
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''5'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>US6069443A</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>05/30/2000</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| FED Corporation
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Passive matrix OLED display
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| The disadvantage of oxygen and moisture penetration into the interior of the organic light emitting device is the potential to form metal oxides at the metal-organic interface. These metal oxide impurities may allow separation of the cathode or anode and the organic in a matrix . This can result in the formation of dark non-emitting spots (i.e., no illumination).Edge shorting between the cathode and anode layers is a current problem affecting most conventional organic light emitting display devices. This edge shorting reduces the illuminating potential of the display devices.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| The present invention to provide an insulator layer to minimize edge shorts between lines by separating the OLED layer and the electrode elements. It also provides a sealing structure to isolate the OLED layer from moisture and other contaminants.
 +
| colspan="7"  style="padding:0.079cm;"|
  
==== Target species ====
+
|-
[[Image:Species.jpg|thumb|center|700px|Target species]]
+
| style="padding:0.079cm;"| <center>'''6'''</center>
 +
| style="padding:0.079cm;"| <center>US20110031511A1</center>
 +
| style="padding:0.079cm;"| <center>02/10/2011</center>
 +
| style="padding:0.079cm;"| None
 +
| style="padding:0.079cm;"| ORGANIC LIGHT EMITTING DIODE DISPLAY AND METHOD OF MANUFACTURING THE SAME
 +
| style="padding:0.079cm;"| In the organic light emitting layer, as it is easy to transfer energy in an interface between a light emitting layer and a hole transfer layer, a light emitting efficiency and lifetime of the OLED display are reduced because of an energy loss of triplet inside the OLED display.
 +
| style="padding:0.079cm;"| An interface of the light emitting layer can be improved by forming the inorganic oxide layer between the hole transport layer and the light emitting layer. Further, an energy loss of triplet can be prevented, and the emission efficiency and lifetime can be improved.
 +
| colspan="7"  style="padding:0.079cm;"|  
  
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''7'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>US20070153051A1</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>07/05/2007</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Samsung Electronics Co., Ltd.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Manufacturing flat panel displays with inkjet printing systems
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| For manufacture of certain flat panel display devices, such as LCDs or OLED displays, various thin film patterns are formed on panel substrates of the devices, typically using photolithography processes. However, as displays become larger, the amount of material that must be deposited on substrates to form the thin film patterns also becomes larger, inturn increases the manufacturing costs of the panels.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Inkjet printing systems have been developed for forming the thin film patterns on the substrates by depositing them on the substrates in the form of special inks. These systems deposit the ink on the substrate through an inkjet head. However, the inkjet head includes a plurality of nozzles, and if only one of these nozzles becomes dysfunctional, the number of passes that the inkjet printing head must make increases. As a result, processing time and costs are substantially increased.
 +
| colspan="7"  style="padding:0.079cm;"|
  
 +
|-
 +
| style="padding:0.079cm;"| <center>'''8'''</center>
 +
| style="padding:0.079cm;"| <center>US6911671B2</center>
 +
| style="padding:0.079cm;"| <center>06/28/2005</center>
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Device for depositing patterned layers in OLED displays
 +
| style="padding:0.079cm;"| To achieve color pixelation in OLED imaging panels, fabrication of a multicolor OLED imaging panel using a shadow masking method is used. A multicolor organic electroluminescent ("EL") medium is vapor deposited and patterned by controlling an angular position of a substrate with respect to a deposition vapor stream. The positioning an element in direct contact with a surface of a substrate can invite problems of abrasion, distortion, or partial lifting, this may cause abrasion, distortion, or partial lifting of the first-color pattern.
 +
| style="padding:0.079cm;"| The present invention is that a pattern of vaporized material, such as organic material, can be deposited without the use of shadow mask.Another feature is that a plurality of devices can be used for simultaneously depositing different organic materials. Such organic materials can emit light in different ranges of the spectrum.
 +
| colspan="7"  style="padding:0.079cm;"|
  
==== Mode of administration ====
+
|-
[[Image:Mode.jpg|thumb|center|700px|Mode of administration]]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''9'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>US7218295B2</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>05/15/2007</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| AU Optronics Corp.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Driving method for active matrix OLED display
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| In one display frame, the current received by the OLED is fixed.The driving method used previously accumulates carriers inside the OLED which reduce the life of the OLEDs. Moreover, the voltage across the OLED gradually increases over timewhich inturn increases power. This effects the OLED over time.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| The present invention uses a driving method to neutralize carrier accumulation in the OLED, thereby reducing the increase in voltage and minimizing the increase in power consumption across both ends of the OLED over time, further increasing the life of the OLED.
 +
| colspan="7"  style="padding:0.079cm;"|
  
 +
|-
 +
| style="padding:0.079cm;"| <center>'''10'''</center>
 +
| style="padding:0.079cm;"| <center>US7067170B2</center>
 +
| style="padding:0.079cm;"| <center>06/27/2006</center>
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Depositing layers in OLED devices using viscous flow
 +
| style="padding:0.079cm;"| To achieve color pixelation in OLED imaging panels, fabrication of a multicolor OLED imaging panel using a shadow masking method is used. A multicolor organic electroluminescent ("EL") medium is vapor deposited and patterned by controlling an angular position of a substrate with respect to a deposition vapor stream. The positioning an element in direct contact with a surface of a substrate can invite problems of abrasion, distortion, or partial lifting, this may cause abrasion, distortion, or partial lifting of the first-color pattern.
 +
| style="padding:0.079cm;"| The present invention is that the method of color pixelating an organic layer includes providing a plurality of vapor sources disposed outside of a deposition chamber for generating vapors of organic materials, and connecting such vapor sources to a manifold disposed in the chamber. By using vapor deposition method, we can eliminate precision shadow masks.
 +
| colspan="7"  style="padding:0.079cm;"|
  
==== Product type vs. Product form ====
+
|}
[[Image:prod.jpg|thumb|center|700px|Product type vs. Product form]]
+
Click '''[[media:sample analysis sheet oled.xls|here]]''' to view the detailed analysis sheet for doubly-fed induction generators patent analysis.
 +
 
 +
==Article Analysis==
 +
{|border="2" cellspacing="0" cellpadding="4" width="100%"
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''S.No.'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Title'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Authors'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Publication date'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Journal/Conference'''</center>
 +
| colspan="2"  style="background-color:#4F81BD;padding:0.079cm;"| <center>Dolcera summery.</center>
 +
 
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''1'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://ieeexplore.ieee.org/xpl/freeabs_all.jsp?arnumber=979337 Application of Screen Printing in the Fabricationof Organic Light-Emitting Devices]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Dino A. Pardo, Ghassan E. Jabbour,* andNasser Peyghambarian
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 01/27/2000
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Optical Sciences Center, University of Arizona.IEEE 27 Jan 2000
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| This article explains the screen printing technique which deposits organic active layer having a thickness of several tens of nanometers and acting as a hole-transport layer (HTL) in multilayer OLEDs. The resulting devices emit<nowiki>light at low voltage (<5 V) and have a peak external quantum efficiency of 0.91 %.</nowiki>
 +
 
 +
|-
 +
| style="padding:0.079cm;"| <center>'''2'''</center>
 +
| style="padding:0.079cm;"| [http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1521-4095(199906)11:9%3C734::AID-ADMA734%3E3.0.CO;2-D/abstract Multicolor Organic Light-Emitting DiodesProcessed by Hybrid Inkjet Printing]
 +
| style="padding:0.079cm;"| Shun-Chi Chang, Jie Liu, Jayesh Bharathan,Yang Yang,* Jun Onohara and Junji Kido
 +
| style="padding:0.079cm;"| 08/07/1999
 +
| style="padding:0.079cm;"| Department of Materials Science and EngineeringUniversity of California at Los Angeles. willey 8 Jul 1999
 +
| style="padding:0.079cm;"| This article presents a multicolor patterning technique to produce controllable patterning of red-green-blue OLEDs with fine pixel displays. The LEDs comprise bilayer structures of red and green dopants with inkjet-printed onto a film of the blue-emitting semiconducting polymer, the latter serving as the hole-transport layer.
 +
 
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''3'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://onlinelibrary.wiley.com/doi/10.1002/pi.1974/abstract Organic light-emitting diode (OLED)technology: materials, devices and displaytechnologies]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Bernard Geffroy, Philippe le Roy and Christophe Prat
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 06/02/2006
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Laboratoire Cellules et Composants. willey 6 Feb 2006
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| This article presents an overview of OLED's over LCD's. OLED'S have a thickness, currently less than 2 mm. Having high contrast ratio is also a strong point of OLED and also in fast response time.OLEDs for flat-panel display applications are their self-emitting property, high luminous efficiency, full-colour capability, wide viewing angle, high contrast,low power consumption, low weight, potentially large area colour displays and flexibility.
 +
 
 +
|-
 +
| style="padding:0.079cm;"| <center>'''4'''</center>
 +
| style="padding:0.079cm;"| [http://www.springerlink.com/content/q34n0017t30373q6/ Organic/polymeric electroluminescent devices processed by hybrid ink-jet printing]
 +
| style="padding:0.079cm;"| Yang Yang, Shun-Chi Chang, Jayesh Bharathan and Jie Liu
 +
| style="padding:0.079cm;"| 04/05/1999
 +
| style="padding:0.079cm;"| Journal of Materials Science: Materials in Electronics Volume 11, Number 2,
 +
| style="padding:0.079cm;"| The HIJP concept is a unique approach for fabricating polymer and organic electronic devices. One is able to apply this technology for the deposition of various functional materials such as charge-injection layers, charge-blocking layers, and multicolor polymer/organic emissive layers. It can be used for the fabrication of logos, indicator lights, multicolor displays and also in bio-medical applications such as biosensors for low cost diagnostics.
 +
 
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''5'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://onlinelibrary.wiley.com/doi/10.1002/adma.200400684/abstract White Organic Light-Emitting Devices for Solid-State Lighting]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| B. W. D'Andrade, S. R. Forrest
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 14/10/2004
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Department of Electrical Engineering, Princeton University Willey 14 OCT 2004
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| This article presents the WOLEDs increasing display applications for use primarily as liquid-crystal display backlights. They have achieved high material purity, low cost, high brightness,color quality and long operational life-times.
 +
 
 +
|-
 +
| style="padding:0.079cm;"| <center>'''6'''</center>
 +
| style="padding:0.079cm;"| [http://www.nature.com/nature/journal/v459/n7244/full/nature08003.html White organic light-emitting diodes with fluorescent tube efficiency]
 +
| style="padding:0.079cm;"| Sebastian Reineke, Frank Lindner, Gregor Schwartz, Nico Seidler, Karsten Walzer
 +
| style="padding:0.079cm;"| 14/05/2009
 +
| style="padding:0.079cm;"| Institute of Applied Photophysics. Vol 459 Macmillan Pub
 +
| style="padding:0.079cm;"| This article presents an WOLED havinh high internal quantum efficiencies for the con-version of electrical energy to light have been realized by focussing on reducing energetic and ohmic losses that occur during electron–photon conversion.This can be achieved by improved OLED structure which reaches fluorescent tube efficiency. By combining a care-fully chosen emitter layer with high-refractive-index substrates and using a periodic outcoupling structure
 +
 
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''7'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://pubs.rsc.org/en/Content/ArticleLanding/2007/JM/b609204g Precision ink jet printing of polymer light emitting displays]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| J. F. Dijksman, P. C. Duineveld, M. J. J. Hack, A. Pierik, J. Rensen, J.-E. Rubingh, I. Schram andM. M. Vernhou
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 09/11/2006
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Philips Research Laboratories RSC
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Precision ink jet printing of organic polymer light emitting diodes relies strongly on the accuracy of the droplet generation process.Image capturing using one image at a time for image processing delivers sharper images and can be used for optically measuring droplet volumes.
 +
 
 +
|-
 +
| style="padding:0.079cm;"| <center>'''8'''</center>
 +
| style="padding:0.079cm;"| [http://apl.aip.org/resource/1/applab/v88/i7/p073517_s1?isAuthorized=no High-efficiency microcavity top-emitting organic light-emittingdiodes using silver anode]
 +
| style="padding:0.079cm;"| Huajun Peng, Jiaxin Sun, Xiuling Zhu, Xiaoming Yu, Man Wong, and Hoi-Sing Kwok
 +
| style="padding:0.079cm;"| 17/02/2006
 +
| style="padding:0.079cm;"| Hong Kong Universityof Science and Technology. AIP
 +
| style="padding:0.079cm;"| High efficient top-emitting OLEDs have been fabricated using highly reflective Ag as the anode. Surfacemodification of the Ag anode by CF4 plasma substantially enhances the hole injection efficiency. The color variation isalmost eliminated in the TOLED. The optimized microcav- ity TOLED has a current efficiency enhancement of 65% and a total outcoupling efficiency enhancement of 35%, as compared with a conventional OLED.
 +
 
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''9'''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6THY-4F70JMT-5&_user=10&_coverDate=05%2F15%2F2005&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1660089209&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=f4dc4db9a6e736e6994a9ffa868e34b8&searchtype=a Inverted top-emitting organic light-emitting diodes using transparent conductive NiO electrode ]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Se-W. Park, Jeong-M. Choi, Eugene Kim and Seongil Im
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 09/01/2005
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Institute of Physics and Applied Physics, Applied Surface Science 244 (2005) 439–443
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| TE-OLED device uses a thermally evaporated and semi-transparent NiO film as a top-electrode. Since the sheet resistance of our NiO was very high and its transmittance was only about 50%, the resulting luminance and injection current of our TE-OLED were much inferior to those of the BE-OLED device.
 +
 
 +
|-
 +
| style="padding:0.079cm;"| <center>'''10'''</center>
 +
| style="padding:0.079cm;"| [http://apl.aip.org/resource/1/applab/v89/i23/p233513_s1?isAuthorized=no Self-assembled monolayer-modified Ag anode for top-emitting polymerlight-emitting diodes]
 +
| style="padding:0.079cm;"| Lai-Wan Chong, Yuh-Lang Lee,a͒ and Ten-Chin Wenb͒
 +
| style="padding:0.079cm;"| 07/12/2006
 +
| style="padding:0.079cm;"| Department of Chemical Engineering, National Cheng Kung University
 +
| style="padding:0.079cm;"| Self-assembled monolayer is a method to modify the Ag anodes for application in T-PLED. The Ag electrode can be utilized as an effective anode to improve the emitting characteristic of a T-PLED. The Ag anode enhances the hole injection, reduce the op-eration voltage, and significantly increase the current inten-sity and luminous efficiency of the device, without decreasing the reflectivity of the Ag anode.
  
==== Patents by target diseases ====
 
{| border="1" cellpadding="16", style="#008080"
 
!width="800" bgcolor=DodgerBlue|'''Target disease/ disorder'''
 
!width="150" bgcolor=DodgerBlue|'''Patent no.'''
 
!width="150" bgcolor=DodgerBlue|'''Rec. no.'''
 
|- 
 
|bgcolor=LightCyan|Alopecia areata, alopecia pityrodes or alopecia seborrheica, or androgenic alopecia (i.e. male pattern baldness)
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220020052498%22.PGNR.&OS=DN/20020052498&RS=DN/20020052498 US20020052498]
 
|bgcolor=LightCyan|1
 
|- 
 
|bgcolor=LightCyan|Alopecia areata, male pattern baldness and female pattern baldness
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220030007941%22.PGNR.&OS=DN/20030007941&RS=DN/20030007941 US20030007941]
 
|bgcolor=LightCyan|2
 
|- 
 
|bgcolor=LightCyan|Androgenic alopecia (i.e. male pattern baldness), prostatic hyperplasia or both.
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060009430%22.PGNR.&OS=DN/20060009430&RS=DN/20060009430 US20060009430]
 
|bgcolor=LightCyan|3
 
|- 
 
|bgcolor=LightCyan|Inappropriate activation of the androgen receptor, acne, oily skin, alopecia
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060009427%22.PGNR.&OS=DN/20060009427&RS=DN/20060009427 US20060009427]
 
|bgcolor=LightCyan|4
 
|-
 
|bgcolor=LightCyan|Prostatic hyperplasia, prostatic cancer, hirsutism, acne, male pattern baldness, seborrhea, and other diseases related to androgen hyperactivity
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050118282%22.PGNR.&OS=DN/20050118282&RS=DN/20050118282 US20050118282]
 
|bgcolor=LightCyan|5
 
|- 
 
|bgcolor=LightCyan|Alopecia, acne, oily skin, prostrate cancer, hirsutism, and benign prostate hyperplasia
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050085467%22.PGNR.&OS=DN/20050085467&RS=DN/20050085467 US20050085467]
 
|bgcolor=LightCyan|6
 
|- 
 
|bgcolor=LightCyan|Androgen-associated hair loss and androgen-skin related disorders.
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060009429%22.PGNR.&OS=DN/20060009429&RS=DN/20060009429 US20060009429]
 
|bgcolor=LightCyan|7
 
|- 
 
|bgcolor=LightCyan|Androgenetic or androgenic alopecia or androgeno-genetic alopecia
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220030073616%22.PGNR.&OS=DN/20030073616&RS=DN/20030073616 US20030073616]
 
|bgcolor=LightCyan|8
 
|- 
 
|bgcolor=LightCyan|Diseases caused by testosterone (male-pattern alopecia)
 
|bgcolor=LightCyan|[http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=EP0279010&F=0 EP0279010]
 
|bgcolor=LightCyan|9
 
|- 
 
|bgcolor=LightCyan|Alopecia areata, female pattern hair loss, hair loss secondary to chemotherapy or radiation treatment, stress-related hair loss, self-induced hair loss, scarring alopecia, and alopecia in non-human mammal
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220040157856%22.PGNR.&OS=DN/20040157856&RS=DN/20040157856 US20040157856]
 
|bgcolor=LightCyan|10
 
|- 
 
|bgcolor=LightCyan|Male pattern alopecia
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050053572%22.PGNR.&OS=DN/20050053572&RS=DN/20050053572 US20050053572]
 
|bgcolor=LightCyan|11
 
|- 
 
|bgcolor=LightCyan|Alopecia, androgenic alopecia
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220060052405%22.PGNR.&OS=DN/20060052405&RS=DN/20060052405 US20060052405]
 
|bgcolor=LightCyan|12
 
|- 
 
|bgcolor=LightCyan|Hair loss
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050123577%22.PGNR.&OS=DN/20050123577&RS=DN/20050123577 US20050123577]
 
|bgcolor=LightCyan|13
 
|- 
 
|bgcolor=LightCyan|Male pattern alopecia
 
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6447762.PN.&OS=PN/6447762&RS=PN/6447762 US6447762]
 
|bgcolor=LightCyan|14
 
|- 
 
|bgcolor=LightCyan|Androgenetic, androgenic or androgenogenetic alopecia
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220040071647%22.PGNR.&OS=DN/20040071647&RS=DN/20040071647 US20040071647]
 
|bgcolor=LightCyan|15
 
|- 
 
|bgcolor=LightCyan|Curing other scalp related problems
 
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050244362%22.PGNR.&OS=DN/20050244362&RS=DN/20050244362 US20050244362]
 
|bgcolor=LightCyan|16
 
 
|}
 
|}
  
==== Patents by application ====
+
Click '''[[media:Non patent literature.xls|here]]''' to view the detailed analysis sheet for Top Emission OLED for non patent literature
[[Image:application.jpg|thumb|center|700px|Distribution of patents based on application]]
+
  
==== [[List of patents]] ====
+
== Top Cited Patents==
== Pathways and linkages ==
+
{|border="2" cellspacing="0" cellpadding="4" width="100%"
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''S. No.'''</center>
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Patent/Publication No.'''</center>
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Publication Date (mm/dd/yyyy)'''</center>
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Assignee/Applicant'''</center>
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Title'''</center>
 +
| style="background-color:#4f81bd;padding:0.079cm;"| <center>'''Citation Count'''</center>
  
=== Pathways associated with hair matrix cell activation===
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>1</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| US6096496A
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>8/1/2000</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Frankel; Robert D
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>130</center>
  
'''Molecular mediators of hair follicle embryogenesis:''' Identification of the molecular pathways controlling differentiation and proliferation in mammalian hair follicles provides the crucial link to understanding the regulation of normal hair growth, the basis of hereditary hair loss diseases, and the origin of follicle-based tumors. Homeobox (hox), hedgehog (hh), patched (ptc), wingless (wg}/wnt, disheveled (dsh), engrailed (en), Notch 1 and armadillo/B-catenin genes are all critical for hair follicle.
+
|-
 +
| style="padding:0.079cm;"| <center>2</center>
 +
| style="padding:0.079cm;"| US6069443A
 +
| style="padding:0.079cm;"| <center>5/30/2000</center>
 +
| style="padding:0.079cm;"| Fed Corporation
 +
| style="padding:0.079cm;"| Passive matrix OLED display
 +
| style="padding:0.079cm;"| <center>97</center>
  
* '''Wnt pathway:''' Maintains hair-inducing activity of the dermal papilla.
+
|-
* '''Hedgehog pathway:''' Sonic hedgehog (SHH) signaling plays a critical role in hair follicle development. Sonic hedgehog gene. Sonic hedgehog, SHH for short, helps guide hair follicles from a resting stage into growth activity. SHH is particularly important in the embryonic formation of hair follicles.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>3</center>
* '''STAT pathway'''
+
| style="background-color:#DCE6F1;padding:0.079cm;"| US6366017B1
* '''TGF beta/BMP Pathway:'''  Bone morphogenetic protein (BMP) signaling have been implicated in the regulation of both proliferation and differentiation in the hair follicle. BMP2 is expressed in the embryonic ectoderm, but then localizes to the early hair follicle placode and underlying mesenchyme. BMP4 is expressed in the early dermal condensate. Research results show that BMPs are a key component of the signaling network controlling hair development and are required to induce the genetic program regulating hair shaft differentiation in the anagen hair follicle. Transforming growth factor beta (TGF-beta), inhibits mitogen - induced dermal papilla cell proliferation
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>4/2/2002</center>
* '''FGF Pathway:''' Fibroblast growth factor (bFGF) and platelet-derived growth factor (PDGF) potentiate the growth of dermal papilla cells. It is proposed that these proteins increase the synthesis of stromelysin (an enzyme, matrix metalloproteinase) which acts on the papilla cells and accelerates their growth.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Agilent Technologies
* '''MAPK Pathway:''' Mitogen-activated protein kinase (MAPK) activation, increases keratinocyte turnover.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Organic light emitting diodes with distributed bragg reflector
* '''NOTCH Pathway''': Notch-1 is expressed in ectodermal-derived cells of the follicle, in the inner cells of the embryonic placode and the follicle bulb, and in the suprabasal cells of the mature outer root sheath. Delta-1, one of the three ligands is only expressed during embryonic follicle development and is exclusive to the mesenchymal cells of the pre-papilla located beneath the follicle placode, and appears to promote and accelerate placode formation, while suppressing placode formation in surrounding cells. Other ligands, Serrate 1 and Serrate 2, are expressed in matrix cells destined to form the inner root sheath and hair shaft.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>80</center>
  
=== Pathways associated with Anti Androgen===
 
[[Image:Slide1.GIF|thumb|center|700 px|Alopecia pathways]]
 
==== Players of WNT inhibition Pathway ====
 
[[Image:wnt.jpg|thumb|right|200 px|Wnt inhibition]]
 
{| border="1" cellpadding="15", style="#008080"
 
!width="150" bgcolor=DodgerBlue|'''Patent no.'''
 
!width="200" bgcolor=DodgerBlue|'''Key compound'''
 
!width="200" bgcolor=DodgerBlue|'''Players of inhibition'''
 
|- style="height:10px"
 
|bgcolor=lightyellow|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6664247.PN.&OS=PN/6664247&RS=PN/6664247 US6664247]
 
|bgcolor=lightyellow|Pyrazole compounds
 
|bgcolor=lightyellow|GSK3
 
 
|-
 
|-
|bgcolor=lightyellow|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6989385.PN.&OS=PN/6989385&RS=PN/6989385 US6989385]
+
| style="padding:0.079cm;"| <center>4</center>
|bgcolor=lightyellow|Pyrazole compounds
+
| style="padding:0.079cm;"| US20020197511A1
|bgcolor=lightyellow|GSK3
+
| style="padding:0.079cm;"| <center>12/26/2002</center>
 +
| style="padding:0.079cm;"| United Of America As Respresented By The Secretary Of The Air Force
 +
| style="padding:0.079cm;"| High efficiency multi-color electro-phosphorescent OLEDS
 +
| style="padding:0.079cm;"| <center>51</center>
 +
 
 
|-
 
|-
|bgcolor=lightyellow|[http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=WO2005012256&F=0 WO2005012256]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>5</center>
|bgcolor=lightyellow|Pyrazole compounds
+
| style="background-color:#DCE6F1;padding:0.079cm;"| US6265820B1
|bgcolor=lightyellow|CDK,GSK3
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>7/24/2001</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Emagin Corporation,De
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Heat removal system for use in organic light emitting diode displays having high brightness
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>50</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6974819.PN.&OS=PN/6974819&RS=PN/6974819 US6974819]
+
| style="padding:0.079cm;"| <center>6</center>
|bgcolor=LightCyan|Pyrimidine derivative
+
| style="padding:0.079cm;"| US20020195968A1
|bgcolor=LightCyan|GSK3
+
| style="padding:0.079cm;"| <center>12/26/2002</center>
 +
| style="padding:0.079cm;"| IBM
 +
| style="padding:0.079cm;"| Oled current drive pixel circuit
 +
| style="padding:0.079cm;"| <center>44</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6743791.PN.&OS=PN/6743791&RS=PN/6743791 US6743791]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>7</center>
|bgcolor=LightCyan|Heterocyclic compounds
+
| style="background-color:#DCE6F1;padding:0.079cm;"| US20020186209A1
|bgcolor=LightCyan|AKT3, GSK-3, ERK2
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>12/12/2002</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Eastman Kodak Company
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Touch screen for use with an OLED display
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>42</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050277773%22.PGNR.&OS=DN/20050277773&RS=DN/20050277773 US20050277773]
+
| style="padding:0.079cm;"| <center>8</center>
|bgcolor=LightCyan|Pyrrolo[3,2-d]pyrimidine derivatives
+
| style="padding:0.079cm;"| US20030127973A1
|bgcolor=LightCyan|GSK3
+
| style="padding:0.079cm;"| <center>7/10/2003</center>
 +
| style="padding:0.079cm;"| Universal Display Corporation
 +
| style="padding:0.079cm;"| OLEDs having increased external electroluminescence quantum efficiencies
 +
| style="padding:0.079cm;"| <center>41</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220040072836%22.PGNR.&OS=DN/20040072836&RS=DN/20040072836 US20040072836]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>9</center>
|bgcolor=LightCyan|Aza-oxindole derivatives
+
| style="background-color:#DCE6F1;padding:0.079cm;"| US6844673B1
|bgcolor=LightCyan|GSK3, AKT, PKC
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>1/18/2005</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Alien Technology Corporation
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Split-fabrication for light emitting display structures
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>38</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=EP1477489&F=0 EP1477489]
+
| style="padding:0.079cm;"| <center>10</center>
|bgcolor=LightCyan|Pyrrolopyrimidine derivatives
+
| style="padding:0.079cm;"| US20040174116A1
|bgcolor=LightCyan|GSK3
+
| style="padding:0.079cm;"| <center>9/9/2004</center>
 +
| style="padding:0.079cm;"| Universal Display Corporation
 +
| style="padding:0.079cm;"| Transparent electrodes
 +
| style="padding:0.079cm;"| <center>36</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=WO0056710&F=0 WO0056710]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>11</center>
|bgcolor=LightCyan|3-(Anilinomethylene) oxindoles
+
| style="background-color:#DCE6F1;padding:0.079cm;"| US20050194896A1
|bgcolor=LightCyan|GSK3, AKT, PKC
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>9/8/2005</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Hitachi Displays Ltd.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Light emitting element and display device and illumination device using the light emitting element
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>35</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=WO03011287&F=0 WO2003011287]
+
| style="padding:0.079cm;"| <center>12</center>
|bgcolor=LightCyan|Pyrazolon derivatives
+
| style="padding:0.079cm;"| US20020074935A1
|bgcolor=LightCyan|GSK3, ß-catenin
+
| style="padding:0.079cm;"| <center>6/20/2002</center>
 +
| style="padding:0.079cm;"| Universal Display Corporation
 +
| style="padding:0.079cm;"| Highly stable and efficient OLEDs with a phosphorescent-doped mixed layer architecture
 +
| style="padding:0.079cm;"| <center>35</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6924141.PN.&OS=PN/6924141&RS=PN/6924141 US6924141]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>13</center>
|bgcolor=LightCyan|Lithium chloride, Wnt3/4/ 7
+
| style="background-color:#DCE6F1;padding:0.079cm;"| US20040217702A1
|bgcolor=LightCyan|ß-catenin, GSK3, Wnt
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>11/4/2004</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Corning Incorporated
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Light extraction designs for organic light emitting diodes
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>33</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6706685.PN.&OS=PN/6706685&RS=PN/6706685 US6706685]
+
| style="padding:0.079cm;"| <center>14</center>
|bgcolor=LightCyan|Peptide sequence
+
| style="padding:0.079cm;"| US20020030647A1
|bgcolor=LightCyan|ß-catenin
+
| style="padding:0.079cm;"| <center>3/14/2002</center>
 +
| style="padding:0.079cm;"| Universal Display Corporation
 +
| style="padding:0.079cm;"| Uniform active matrix oled displays
 +
| style="padding:0.079cm;"| <center>32</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6683048.PN.&OS=PN/6683048&RS=PN/6683048 US6683048]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>15</center>
|bgcolor=LightCyan|Peptide sequence
+
| style="background-color:#DCE6F1;padding:0.079cm;"| US20050248270A1
|bgcolor=LightCyan|a-catenin, ß-catenin
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>11/10/2005</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Eastman Kodak Company
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Encapsulating OLED devices
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>31</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6677116.PN.&OS=PN/6677116&RS=PN/6677116 US6677116]
+
| style="padding:0.079cm;"| <center>16</center>
|bgcolor=LightCyan|Peptide sequence  LXXLL
+
| style="padding:0.079cm;"| US20040113875A1
|bgcolor=LightCyan|ß-catenin
+
| style="padding:0.079cm;"| <center>6/17/2004</center>
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Color oled display with improved power efficiency
 +
| style="padding:0.079cm;"| <center>29</center>
 +
 
 
|-
 
|-
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6303576.PN.&OS=PN/6303576&RS=PN/6303576 US6303576]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>17</center>
|bgcolor=LightCyan|Peptide sequence  LXXLL
+
| style="background-color:#DCE6F1;padding:0.079cm;"| US20030230972A1
|bgcolor=LightCyan|ß-catenin
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>12/18/2003</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Eastman Kodak Company
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Oled display having color filters for improving contrast
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>28</center>
 +
 
 +
|-
 +
| style="padding:0.079cm;"| <center>18</center>
 +
| style="padding:0.079cm;"| US20050040756A1
 +
| style="padding:0.079cm;"| <center>2/24/2005</center>
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| OLED device having microcavity gamut subpixels and a within gamut subpixel
 +
| style="padding:0.079cm;"| <center>27</center>
 +
 
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>19</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| US6670772B1
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>12/30/2003</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Eastman Kodak Company
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Organic light emitting diode display with surface plasmon outcoupling
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>26</center>
 +
 
 +
|-
 +
| style="padding:0.079cm;"| <center>20</center>
 +
| style="padding:0.079cm;"| US20040061136A1
 +
| style="padding:0.079cm;"| <center>4/1/2004</center>
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Organic light-emitting device having enhanced light extraction efficiency
 +
| style="padding:0.079cm;"| <center>26</center>
 +
 
 
|}
 
|}
  
==== Role of Pyrazole compounds in Wnt Pathway====
+
== Top Cited Articles ==
'''Pyrazole'''
+
{|border="2" cellspacing="0" cellpadding="4" width="100%"
* '''Pyrazole''' (C3H4N2) refers both to the class of simple aromatic ring organic compounds of the heterocyclic series characterized by a 5-membered ring structure composed of three carbon atoms and two nitrogen atoms in adjacent positions and to the unsubstituted parent compound. Being so composed and having pharmacological effects on humans, they are classified as alkaloids although they are not known to occur in nature.
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''S. No.'''</center>
* Pyrazoles are produced synthetically through the reaction of a,ß-unsaturated aldehydes with hydrazine and subsequent dehydrogenation
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Title'''</center>
[[Image:pyrazole1.jpg|thumb|center|500px|Pyrazole (C3H4N2)]]
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Publication Date'''</center>
* Pyrazoles are used for their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, tranquilizing, muscle relaxing, psychoanaleptic, anticonvulsant, monoamineoxidase inhibiting, antidiabetic and antibacterial activities.
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Journal/Conference'''</center>
* Structurally related compounds are pyrazoline and pyrazolidine.
+
| colspan="2"  style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Citations Count'''</center>
[[Image:pyrazole2.jpg|thumb|center|500px|Structurally related compounds]]
+
  
==== GSK3 inhibition by pyrazole compounds ====
+
|-
[[Image:bold3.jpg]]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>1</center>
{| border="1" cellpadding="2", style="#008080"
+
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://www.nature.com/nature/journal/v420/n6917/full/nature01217.html?free=2 Electroluminescence from single monolayers of nanocrystals in molecular organic devices]
!width="350"|[http://patft1.uspto.gov/netacgi/nph-Parser?TERM1=6989385+&Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=0&f=S&l=50 US6989385]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>Oct 2002</center>
[[Image:US6989385.jpg]]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Nature, Internatinal journal of science.
!width="350"|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6664247.PN.&OS=PN/6664247&RS=PN/6664247 US6664247]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>736</center>
[[Image:US6664247.jpg]]
+
!width="350"|[http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=WO2005012256&F=0 WO2005012256]  
+
[[Image:WO2005012256.jpg]]
+
|-
+
|bgcolor=lightcyan|R1=T-Ring D, wherein
+
T is a valence bond and
+
Ring D = 5-6 membered aryl or heteroaryl ring;  
+
  
R2 = hydrogen or C1-4 aliphatic and
+
|-
R2'= hydrogen;  
+
| style="padding:0.079cm;"| <center>2</center>
 +
| style="padding:0.079cm;"| [http://www.nature.com/nature/journal/v413/n6858/abs/413828a0.html Spin-dependent exciton formation in π-conjugated compounds]
 +
| style="padding:0.079cm;"| <center>Aug 2001</center>
 +
| style="padding:0.079cm;"| Nature, Internatinal journal of science.
 +
| style="padding:0.079cm;"| <center>220</center>
  
R3 = -R, -OR, or -N(R4)2, wherein
+
|-
R = hydrogen, C1-6 aliphatic, 5-6 membered heterocyclyl, phenyl, or 5-6 membered heteroaryl, and
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>3</center>
L is -O-, -S-, or -NH-; and
+
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://pubs.acs.org/doi/abs/10.1021/cr050156n Highly Efficient Organic Devices Based on Electrically Doped Transport Layers]
Ring D is substituted by up to three substituents selected from -halo, -CN, -NO2, -N(R4)2, optionally substituted C1-6 aliphatic group, -OR, -C(O)R, -CO2R, -CONH(R<4>), -N(R4)COR, -N(R4)CO2R, -SO2N(R4)2, -N(R4)SO2R, -N(R6)COCH2N(R4)2, -N(R6)COCH2CH2N(R4)2, or -N(R6)COCH2CH2CH2N(R4)2, wherein R = hydrogen, C1-6 aliphatic, phenyl, 5-6 membered heteroaryl ring, or 5-6 membered heterocyclic ring
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>Mar 2007</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| American Chemical Society Pub.
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>211</center>
  
|bgcolor=lightcyan|X = R1-A-NR4- or a 5- or 6-membered carbocyclic or heterocyclic ring; A is a bond, S02, C=O, NRg(C=O) or O(C=O) wherein Rg is hydrogen or C1-4 hydrocarbyl optionally substituted by hydroxy or C1-4 alkoxy; Y is a bond or an alkylene chain of 1, 2 or 3 carbon atoms in length;  
+
|-
 +
| style="padding:0.079cm;"| <center>4</center>
 +
| style="padding:0.079cm;"| [http://apl.aip.org/resource/1/applab/v82/i3/p466_s1?isAuthorized=no Phosphorescent top-emitting organic light-emitting devices with improved light outcoupling]
 +
| style="padding:0.079cm;"| <center>Nov 2002</center>
 +
| style="padding:0.079cm;"| Applied Physics Letters / Volume 82
 +
| style="padding:0.079cm;"| <center>111</center>
  
R1 is hydrogen; carbocyclic or heterocyclic group having from 3 to 12 ring members; or  C1-8 hydrocarbyl group optionally substituted by one or more substituents selected from halogen (e.g. fluorine), hydroxy, C1-4 hydrocarbyloxy, amino, mono- or di-C1-4 hydrocarbylamino, and carbocyclic or heterocyclic groups having from 3 to 12 ring members, and wherein 1 or 2 of the carbon atoms of the hydrocarbyl group may optionally be replaced by an atom or group selected from 0, S, NH, SO, S02;  
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>5</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://ieeexplore.ieee.org/xpl/freeabs_all.jsp?arnumber=1288072 Thin-film permeation-barrier technology for flexible organic light-emitting devices]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>Jan 2004</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| IEEE Photonics Society
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>104</center>
  
R2 is hydrogen; halogen; C1-4 alkoxy (e.g. methoxy); or a C1-4 hydrocarbyl group optionally substituted by halogen (e.g. fluorine), hydroxyl or C1-4 alkoxy (e.g. methoxy); R3 is selected from hydrogen and carbocyclic and heterocyclic groups having from 3 to 12 ring members; and  
+
|-
 +
| style="padding:0.079cm;"| <center>6</center>
 +
| style="padding:0.079cm;"| [http://ieeexplore.ieee.org/xpl/freeabs_all.jsp?arnumber=669473 Design of flat-panel displays based on organic light-emitting devices]
 +
| style="padding:0.079cm;"| <center>Feb 1998 </center>
 +
| style="padding:0.079cm;"| IEEE Photonics Society
 +
| style="padding:0.079cm;"| <center>100</center>
 +
 
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>7</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://ieeexplore.ieee.org/xpl/freeabs_all.jsp?arnumber=1224525 A new a-Si:H thin-film transistor pixel circuit for active-matrix organic light-emitting diodes]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>Aug 2003</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| IEEE Electron Devices Society
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>86</center>
 +
 
 +
|-
 +
| style="padding:0.079cm;"| <center>8</center>
 +
| style="padding:0.079cm;"| [http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6W6J-49KS3CB-1&_user=10&_coverDate=09%2F30%2F2003&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1688490500&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=ea20da18e92aafacab19ac69101f9a3c&searchtype=a The road to high efficiency organic light emitting devices ]
 +
| style="padding:0.079cm;"| <center>Sep 2003</center>
 +
| style="padding:0.079cm;"| ScienceDirect
 +
| style="padding:0.079cm;"| <center>87</center>
 +
 
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>9</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| [http://ieeexplore.ieee.org/xpl/freeabs_all.jsp?arnumber=1327745 Amorphous silicon thin film transistor circuit integration for organic LED displays on glass and plastic]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>Sep 2004</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| IEEE Photonics Society
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>73</center>
 +
 
 +
|-
 +
| style="padding:0.079cm;"| <center>10</center>
 +
| style="padding:0.079cm;"| [http://apl.aip.org/resource/1/applab/v82/i16/p2715_s1?isAuthorized=no Transparent-cathode for top-emission organic light-emitting diodes ]
 +
| style="padding:0.079cm;"| <center>Feb 2003</center>
 +
| style="padding:0.079cm;"| Applied Physics Letters
 +
| style="padding:0.079cm;"| <center>72</center>
  
R4 is hydrogen or a C1-4 hydrocarbyl group optionally substituted by halogen (e.g. fluorine), hydroxyl or C1-4 alkoxy (e.g. methoxy).
 
 
|bgcolor=lightcyan|X is a groupR1-A-NR4-or a 5-or 6-membered carbocyclic or heterocyclic ring;
 
A is a bond,SO2, C=O, NRg (C=O) or O(C=O) wherein Rg is hydrogen orC14 hydrocarbyl optionally substituted by hydroxy or C1-4 alkoxy;Y is a bond or an alkylene chain of 1,2 or 3 carbon atoms in length;R'is hydrogen; a carbocyclic or heterocyclic group having from 3 to 12 ring members; or a C1-8 hydrocarbyl group optionally substituted by one or more substituents selected from halogen (e. g. fluorine), hydroxy, C1-4 hydrocarbyloxy, amino, mono-ordi-Cl 4 hydrocarbylamino, and carbocyclic or heterocyclic groups having from 3 to 12 ring members, and wherein 1 or 2 of the carbon atoms of the hydrocarbyl group may optionally be replaced by an atom or group selected fromO, S, NH, SO, SO2 ;R2 is hydrogen; halogen;C14 alkoxy (e. g. methoxy); or aC14 hydrocarbyl group optionally substituted by halogen (e. g. fluorine), hydroxyl orC14 alkoxy (e. g. methoxy);R3 is selected from hydrogen and carbocyclic and heterocyclic groups having from 3 to 12 ring members; andR4 is hydrogen or a C1-4 hydrocarbyl group optionally substituted by halogen (e. g. fluorine), hydroxyl or C1-4 alkoxy (e. g. methoxy).
 
 
|}
 
|}
  
==== Inhibition by amine derivatives ====
+
= Dolcera Dashboard =
 +
[[Image:dashboard_features.png|center|750px|]]
  
'''Patent Number''': US6989385
+
'''Dashboard Link'''<br>
'''Applicant''': ''Vertex Pharmaceuticals Incorporated''
+
{|border="2" cellspacing="0" cellpadding="4" width="100%"
'''Title''': Pyrazole compounds useful as protein kinase inhibitors
+
|'''[http://www.dolcera.com/auth/dashboard/dashboard.php?workfile_id=913 Top Emission OLED - Dashboard] '''
 +
|width="100"|[[Image:dashboard_thumb.png|center|100px|]]
 +
|-
 +
|}
 +
*Flash Player is essential to view the Dolcera dashboard
  
'''Basic Structure''':
+
=Products=
  
[[Image:pyrazol1.jpeg]]
+
{|border="2" cellspacing="0" cellpadding="4" width="100%"
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''S. No.'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Company'''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Product'''</center>
 +
| colspan="2"  style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Specifications'''</center>
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;" rowspan="14"| <center>1</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;" rowspan="14"| <center>[http://pro.sony.com/bbsc/ssr/product-BVME250/ Sony] </center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;" rowspan="14"| [[Image:oled 2.png]] <center>[http://pro.sony.com/bbsc/ssr/product-BVME250/ BVME250]
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Digital Inputs Specifications'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Detail:'''
  
[[Derivatives of pyrimidine-pyrazole amine disclosed in US6989385 patent]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| HDMI
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| HDMI (x1) (HDCP correspondence, Deep Color correspondence)
  
'''Patent Number''': US7008948
+
|-
'''Applicant''': Vertex Pharmaceuticals Incorporated
+
| style="background-color:#DCE6F1;padding:0.079cm;"| SDI (SMPTE 259M)
'''Title''': Fused pyrimidyl pyrazole compounds useful as protein kinase inhibitors
+
| style="background-color:#DCE6F1;padding:0.079cm;"| BNC (x2)
  
'''Basic Structure'''
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Display Specifications'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Detail:'''
  
[[Image:pyrazol2.jpeg]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Image Aspect Ratio
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 16:09
  
[[Derivatives of pyrimidine-pyrazole amine disclosed in US7008948 patent]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Resolution
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 1920 x 1080 pixels (Full HD)
  
'''Patent Number''': US6977262
+
|-
'''Assignee''': Mitsubishi Pharma Corporation
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Screen Size
'''Title''': Dihydropyrazolopyridine compounds and pharmaceutical use thereof
+
| style="background-color:#DCE6F1;padding:0.079cm;"| 24 5/8 inches (623.4 mm)
  
'''Basic Structure''':
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Viewing Angle
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 89°/89°/89°/89°
  
[[Image:pyrazol3.jpeg]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''General Specifications Specifications'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Detail:'''
  
[[Derivatives of pyrimidine-pyrazole amine disclosed in US6977262 patent]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Dimensions (W x H x D)
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 22 3/4 x 16 3/4 x 5 7/8 inches
  
----
+
|-
'''Patent Number''': US6664247
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Weight
'''Assignee''': Vertex Pharmaceuticals Incorporated
+
| style="background-color:#DCE6F1;padding:0.079cm;"| 28 lb 11 oz
'''Title''': Pyrazole compounds useful as protein kinase inhibitors'''
+
  
'''Basic Structure''':  
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Power Requirements Specifications'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Detail:'''
  
[[Image:pyrazol4.jpeg]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Power Consumption
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Approx. 145 W
  
[[Derivatives of pyrimidine-pyrazole amine disclosed in US6664247 patent]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Power Requirements
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| AC 100 V to 240 V, 1.6 A to 0.8 A, 50/60 Hz
  
----
+
|-
'''Patent Number''': US2004224944
+
| style="padding:0.079cm;" rowspan="14"| 2</center>
'''Assignee''': VERTEX PHARMACEUTICALS INC
+
| style="padding:0.079cm;" rowspan="14"| <center>[http://www.sony.co.uk/biz/product/bvm/bvm-e170/overview Sony]</center>
'''Title''': Pyrazole compounds useful as protein kinase inhibitors
+
| style="padding:0.079cm;"  rowspan="14"|[[Image:oled 3.png]]<br> <center>[http://www.sony.co.uk/biz/product/bvm/bvm-e170/overview BVM-E170]</center>
 +
| style="padding:0.079cm;"| '''Digital Inputs Specifications'''
 +
| style="padding:0.079cm;"| '''Detail:'''
 +
|-
 +
| style="padding:0.079cm;"| HDMI
 +
| style="padding:0.079cm;"| HDMI (x1) (HDCP correspondence, deep colour correspondence)
  
'''Basic Structure''':  
+
|-
 +
| style="padding:0.079cm;"| SDI
 +
| style="padding:0.079cm;"| BNC (x2)
  
[[Image:pyrazol5.jpeg]]
+
|-
 +
| style="padding:0.079cm;"| '''Display Specifications'''
 +
| style="padding:0.079cm;"| '''Detail:'''
  
[[Derivatives of pyrimidine-pyrazole amine disclosed in US2004224944 patent]]
+
|-
 +
| style="padding:0.079cm;"| Image Aspect Ratio
 +
| style="padding:0.079cm;"| 16:09
  
[[Other derivates for alopecia]]
+
|-
 +
| style="padding:0.079cm;"| Resolution
 +
| style="padding:0.079cm;"| 1920 x 1080 pixels (Full HD)
  
==== GSK-3 Inhibition Mechanism - Phosphorylation====
+
|-
* ''GSK-3 inhibition targets treatment of chemotherapy-induced alopecia''  [http://www.biomedcentral.com/1471-2199/5/15 source]
+
| style="padding:0.079cm;"| Screen Size
* In the canonical Wnt signaling cascade, adenomatous polyposis coli (APC), axin, and GSK3 constitute the so-called destruction complex, which controls the stability of beta-catenin. It is generally believed that four conserved Ser/Thr residues in the N terminus of beta-catenin are the pivotal targets for the constitutively active serine kinase GSK3. GSK3 covalently modifies beta-catenin by attaching phosphate groups (from ATP) to serine, and threonine residues. In so doing, the functional properties of the protein kinase’s substrate (beta-catenin) are modified.
+
| style="padding:0.079cm;"| 365.8 x 205.7 mm (14 1/2 x 8 1/8 inches)
  
* In the absence of Wnt signals, glycogen synthase kinase (GSK) is presumed to phosphorylate the N-terminal end of beta-catenin, thus promote degradation of beta-catenin and subsequent ubiquitination and proteasomal targeting.
+
|-
 +
| style="padding:0.079cm;"| Viewing Angle
 +
| style="padding:0.079cm;"| 89°/89°/89°/89° (typical) (up/down/left/right contrast >10:1)
  
* Exposure of cells to Wnts leads to inactivation of GSK-3 through an as yet unclear mechanism.The phosphoprotein Dishevelled is required, after receptor-ligand interaction, to transduce the signal that results in the inactivation of GSK-3. As a result, beta-catenin is dephosphorylated and escapes the ubiqduitylation-dependent destruction machinery.
+
|-
 +
| style="padding:0.079cm;"| '''General Specifications Specifications'''
 +
| style="padding:0.079cm;"| '''Detail:'''
  
* Unphosphorylated beta-catanin accumulates in the cytoplasm and translocates to the nucleus, where it can associate with the TCF/LEFs and become a transcriptional transactivator.
+
|-
 +
| style="padding:0.079cm;"| Dimensions (W x H x D)
 +
| style="padding:0.079cm;"| 436.0 x 282.4 (266.4)* x 214.7 mm (17 1/4 x 11 1/4 (10 1/2)* x 8 1/2 inches) * Height without legs
  
'''[[More details on GSK-3]]'''
+
|-
 +
| style="padding:0.079cm;"| Weight
 +
| style="padding:0.079cm;"| 8.5 kg (18 lb 11 oz)
  
'''Key points'''
+
|-
 +
| style="padding:0.079cm;"| '''Power Requirements Specifications'''
 +
| style="padding:0.079cm;"| '''Detail:'''
  
* Beta-catenin phosphorylation at serine 45 (Ser45), threonine 41 (Thr41), Ser37, and Ser33 is critical for beta-catenin degradation. [http://jb.oxfordjournals.org/cgi/content/abstract/132/5/697 source]
+
|-
* Regulation of beta-catenin phosphorylation is a central part of the canonical Wnt signaling pathway. [http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ProduktNr=223838&ArtikelNr=66755&filename=66755.pdf source]
+
| style="padding:0.079cm;"| Power Consumption
* Ser-X-X-X-Ser (X is any amino acid) motif is obligatory for beta-catenin phosphorylation by GSK3.[http://lib.bioinfo.pl/auth:He,X source]
+
| style="padding:0.079cm;"| Approx. 65 W normally with input from a standard HDMI input. Approx. 115 W at maximum load, with four option slots in use and maximum luminance compensation for any deterioration due to aging.
* Beta-catenin phosphorylation/degradation and its regulation by Wnt can occur normally in the absence of Thr41 as long as the Ser-X-X-X-Ser motif/spacing is preserved. [httSp://pubs.acs.org/cgi-bin/abstract.cgi/bichaw/2006/45/i16/abs/bi0601149.html source]
+
  
'''GK3 Inhibition:'''
+
|-
 +
| style="padding:0.079cm;"| Power Requirements
 +
| style="padding:0.079cm;"| AC 100 V to 240 V, 1.4 A to 0.7 A, 50/60 Hz DC 24 V to 28 V, 4.7 A to 4.0 A
  
* GSK3 is regulated by phosphorylation.
+
|-
* Phosphorylation of GSK3beta on Ser9 (Ser21 in GSK3alpha) by protein kinase B (PKB) causes its inactivation is the primary mechanism responsible for growth factor inhibition of this kinase. Activation of GSK3beta is dependent upon the phosphorylation of Tyr216 (Tyr279 in GSK3alpha). Upon activation, it has been shown to phosphorylate a number of different cellular proteins, including p53, c-Myc, c-Jun, heat shock factor-1 (HSF-1), beta-catenin and cyclin D1. [http://www.bioreagents.com/index.cfm/fuseaction/products.detail/CatNbr/OPA1-03082 source]
+
| style="background-color:#DCE6F1;padding:0.079cm;" rowspan="18"| <center>3</center>
* GSK3 is inhibited by phosphorylation of serine-9 or serine-21 in GSK3beta and GSK3alpha, respectively. [http://lib.bioinfo.pl/auth:Friedman,AB source]
+
| style="background-color:#DCE6F1;padding:0.079cm;" rowspan="18"| <center>[http://pro.sony.com/bbsc/ssr/product-PVM740/ Sony]</center>
* GSK3’s substrate specificity is unique in that phosphorylation of substrate only occurs if a phosphoserine or phosphotyrosine is present four residues C-terminal to the site of GSK phosphorylation. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11430833&dopt=Abstract source]
+
| style="background-color:#DCE6F1;padding:0.079cm;" rowspan="18"| [[Image:oled 1.png]] <center>[http://pro.sony.com/bbsc/ssr/product-PVM740/ PVM-740 ]</center>
* A phosphorylation cascade starts from GSK3 itself and initiates it in beta-catenin. [http://www.genesdev.org/cgi/content/full/16/16/2073 source]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Digital Inputs Specifications'''
* Thus our goal is to stop the phosphorylation of the serine and threonine residue of GSK3.
+
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Detail:'''
* The figure below illustrates the phosphorylation mechanism of serine and threonine by ATP.  
+
  
[[image:GSK3_phosphorylation.jpg|400 px|center|thumb|Phosphorylation mechanism [http://images.google.com/images?q=tbn:DGnhgZ7y7pSejM:bass.bio.uci.edu/~hudel/bs99a/lecture26/phosphoaa.gif source]]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| HDMI
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Yes
  
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| HDSDI (SMPTE 292M)
 +
| colspan="2"  style="background-color:#DCE6F1;padding:0.079cm;"| 3G/SDI/HDSDI
  
* We can't stop conversion of ADP to ATP that relaseas Phosphorous group causing Phosphorylation.
+
|-
* We can only block the oxygen atom on serine and threonine as a result which will in turn stop Phosphorylation.  
+
| style="background-color:#DCE6F1;padding:0.079cm;"| SDI (SMPTE 259M)
* The two probable ways of blocking the oxygen atom are (a) As oxygen is a Lewis  acid with strong electron donating capacity, so usually a strong electron pair acceptor can easily bind to oxygen atom and preventing phosphorylation or (b) breaking of the -OH bond with the carbon atom.  
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Included
  
'''Serine - pyrazole reaction'''
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Display Specifications'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Detail:'''
  
[[image:serine-pyrazol.jpg|600 px|center|thumb|Serine and Pyrazole reaction [http://www.genome.ad.jp/dbget-bin/www_bget?rn+R03134 source]]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Back Light Technology
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| OLED
  
* The T-loop of GSK-3 is tyrosine phosphorylated at Y216 and Y279 in GSK-3b and GSK-3a, respectively, but not threonine phosphorylated. Y216/Y279 phosphorylation could play a role in forcing open the substrate (e.g, beta-catanin)-binding site.
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Native Aspect Ratio
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| 16:09
  
* Thus, T-loop tyrosine might facilitate substrate phosphorylation but is not strictly required for kinase activity.
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Resolution
 +
| colspan="2"  style="background-color:#DCE6F1;padding:0.079cm;"| 960 x 540
  
* Stimulation of cells with pyrazole compounds cause inactivation of GSK-3 through phosphorylation (S9 of GSK-3 beta and S21 of GSK-3 alpha), which inhibits GSK-3 activity. Thus leading to dephosphorylation of substrates (e.g., beta-catanin) resulting in their functional activation and consequent increased hair follicle morphogenisis.
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Screen Size
 +
| colspan="2"  style="background-color:#DCE6F1;padding:0.079cm;"| Approx 7.4 inches
  
* Phosphorylation of S9/S21 creates a primed pesudosubstrate that binds intramolecularly to the positively charged pocket of the GSK-3. This folding precludes phosphorylation of substrates (eg., beta-catanin) because the catalytic groove is occupied. The mechanism of inhibition is competitive.  
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Viewing Angle
 +
| colspan="7"  style="background-color:#DCE6F1;padding:0.079cm;"| 85°/85°/85°/85° (typical) (up/down/left/right contrast>10:1)
  
* A consequence of this is that primed substrates, in high enough concentrations, out-compete the pesudosubstrate and thus become phosphorylated.
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''General Specifications Specifications'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Detail:'''
  
* Thus, small molecule inhibitors modeled to fit in the positively charged pocket of the GSK-3 kinease domain could potentially be very effective for selective inhibition of primed substrates.
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Dimensions (W x H x D)
 +
| colspan="7"  style="background-color:#DCE6F1;padding:0.079cm;"| 8 7/8 x 7 1/4 x 6 3/8 inches Approx. 222.4 x 183.5 x 161.8 mm
  
'''Proposed mechanisms to regulate GSK-3''' [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12615961 source]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| On-Screen Display
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Yes
  
# inactivation of GSK-3 through serine phosphorylation
+
|-
# activation of GSK-3 through tyrosine phosphorylation
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Rack Mount
# inactivation of GSK-3 through tyrosine dephosphorylation
+
| style="background-color:#DCE6F1;padding:0.079cm;"| MB531
# Covalant modifications of substrates through priming phosphorylation
+
# inhibition or facilation of GSK-3 mediated substrate phosphorylation thriugh interation of GSK-3 with binding or scaffolding proteins
+
# targeting of GSK-3 to different subcellular localizations
+
# differential usage of isoforms or splice variants to alter subcellular localization or substrate specificity
+
# integration of parellel signals conveyed by a signal stimulus.
+
  
'''Key Finding'''
+
|-
* '''Pyrazole compounds with inhibition constant (Ki) of <0.1 mM''' are a good starting point for developing molecules that can inhibit serine/threonine protein kinase (such as GSK-3) and the proteins they help to regulate. [http://www.chemistry.org/portal/a/c/s/1/acsdisplay.html?DOC=patentwatch%5Carchive%5C011204_patentwatch.html source]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Weight
 +
| colspan="4"  style="background-color:#DCE6F1;padding:0.079cm;"| Approx. 5 lb 12 oz Approx. 2.6 kg
  
=== Pathway associated with anti-androgen ===
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Power Requirements Specifications'''
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| '''Detail:'''
  
* Dihydrotestosterone
+
|-
** Formed by peripheral conversion of testosterone by 5-alpha reductase
+
| style="background-color:#DCE6F1;padding:0.079cm;"| Power Consumption
** Binds to androgen receptor on susceptible hair follicles
+
| colspan="2"  style="background-color:#DCE6F1;padding:0.079cm;"| Max. approx. 27W
* Hormone-receptor complex activates genes responsible for gradual transformation of large terminal follicles to miniaturized (progressive diminution of hair shaft diameter and length in response to systemic androgens) follicles
+
  
[[Image:5-alpha-reductase inhibition.jpeg|center|500 px]]
+
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Power Requirements
 +
| colspan="9"  style="background-color:#DCE6F1;padding:0.079cm;"| AC 100 to 240 V 50/60 Hz 0.5A to 0.3A DC 12 V 1.9 A Rechargeable Battery Pack
  
==== Structure-Activity Relationships(SARs) ====
+
|}
[[Image:SAR_map.gif|center|600px]]
+
  
=== Pathway associated with Minoxidil (vasodilators) ===
+
=Market Research=
Minoxidil is a well know drug used for the treatment of alopecia. A co-relation between Sesquiterpene lactone (Helenalin) produced from Arnica montana and Minoxidil is illustrated in the figure below. Arnica montana, a Vasodilator, acts on  the NO/cGMP Pathway through T-cells, B-cells and epithelial cells & abrogates kappa B-driven gene expression.
+
==Major Players==
[[image:vasodiator-rev.jpg|800 px|center]]
+
{|border="2" cellspacing="0" cellpadding="4" width="100%"
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Major types of player '''</center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''USA''' </center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''EU''' </center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Japan''' </center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Korea''' </center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Taiwan''' </center>
 +
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''China''' </center>
  
== Alopecia IPMap ==  
+
|-
[http://www.dolcera.com/client/d8r3/hairloss_map.htm Dolcera IPMap for Alopecia]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''Original IPR for devices and for manufacture process + material supply / verification '''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| UDC; Kodak; Add-Vision; Magin; Plextronics; Organic Lighting Technologies; GE;3M Innovation
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| CDT (Sumitomo Chemical) (UK); Novaled (G); Fraunhofer IPMS (G); OLED-T (UK); OTB (ND); MicroEmissive Displays (UK)
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Seiko-Epson; Matsushita; Sony; Sumitomo Chemical; Sharp; TM Display; Konica –Minolta; Sanyo; Toppoly; Lumiotec; Canon; Toshiba
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Samsung; LG Phillips LCD; Neo View; Doosan DND
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| AU Optoelectronics (AUO); Univision; Toppoly; Tetrahedron; Chi Mei Optoelectronics
 +
| style="background-color:#DCE6F1;padding:0.079cm;"|
  
 +
|-
 +
| style="padding:0.079cm;"| <center>'''Bulk materials and glass suppliers '''</center>
 +
| style="padding:0.079cm;"| PPG; 3M; Dow Corning
 +
| style="padding:0.079cm;"| Merck Materials (G); BASF (G); CDT (UK); Degussa/ Evonik (G); HC Starck (G); Sensient Imaging Technologies (G); Goodfellow Metals (UK); Novaled (G)
 +
| style="padding:0.079cm;"| Sumitomo Chemical; Mitsubishi Chemical
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| Syndychem (Shenyang Syndy Chemistry Institute)
  
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''Components – driver ccts., packaging etc '''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Corning; Rockwell Collins
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| ST Microelectronics (It, Fr); Infineon (G)
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Maekawa; Matsushita; Toppoly
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Dae Joo Electrncs
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| AUO; Richtek Technologies; Lightsonic; Univision; Wintek
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Innocom Technologies Shenzen; RIT Display
  
 +
|-
 +
| style="padding:0.079cm;"| <center>'''OEM OLED FPD screen manufacturer & resellers '''</center>
 +
| style="padding:0.079cm;"| eMagin; US Micro Products
 +
| style="padding:0.079cm;"| Densitron Technologies (UK); MicroEmissive Displays (MED) (UK); Pacer International Distributors (UK reseller)
 +
| style="padding:0.079cm;"| Seiko-Epson; Sharp; Sumitomo Chemical; Lumiotec; TMDisplay; Sanyo
 +
| style="padding:0.079cm;"| Samsung SDI; Orion OLED; NeoView KOLON; Hyundai LCD
 +
| style="padding:0.079cm;"| AUO; Chi Mei EL (CMEL); Univision Technology; Evervision Electronics; RiTDisplay; TPO Display
 +
| style="padding:0.079cm;"| Visionix; Smartdisplays; Universal Display Technologoes (Jilin); Varitronix (HK); Blaze Display Technologies
 +
 +
|-
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| <center>'''Branded application device or/and FPD screen manufacturer with retail device sales '''</center>
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| OSD
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Nokia; Sony-Ericsson
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Sony; Matsushita; Hitachi; Toshiba; Imase
 +
| style="background-color:#DCE6F1;padding:0.079cm;"| Samsung; LG Philips
 +
| style="background-color:#DCE6F1;padding:0.079cm;"|
 +
| style="background-color:#DCE6F1;padding:0.079cm;"|
 +
 +
|-
 +
| style="padding:0.079cm;"| <center>'''OLED lighting branded suppliers and R&D '''</center>
 +
| style="padding:0.079cm;"| GE
 +
| style="padding:0.079cm;"| Thorn EMI (UK); OSRAM (G); Siemens (G)
 +
| style="padding:0.079cm;"| Sumitomo Chemica
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
 +
|}
 +
 +
source: [[Media:market.pdf|Major players]]
  
 +
'''SWOT analysis'''
  
== Patent activity in China ==
 
===Treatment approaches===
 
 
{|border="2" cellspacing="0" cellpadding="4" width="100%"
 
{|border="2" cellspacing="0" cellpadding="4" width="100%"
|align = "center"|'''Treatment approach'''
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Strengths '''</center>
|align = "center"|'''Patent number'''
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Weaknesses '''</center>
|align = "center"|'''Priority year'''
+
 
|align = "center"|'''Assignee/Inventor'''
+
 
|-
 
|-
|rowspan = "7"|Vasodilators
+
| style="background-color:#DCE6F1;padding:0.079cm;"| • Capability for innovation<br>• Production of base materials for OLED manufacture <br>• Process equipment manufacture is easy.
|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN200510107497.8&leixin=fmzl&title=治疗瘀血阻滞型脱发的中草药汤剂及制备方法&ipc=A61K36/804(2006.01)I CN1772105]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| • Lack of industrial productive capacity or eco-system to support low-cost volume production<br> • Capability to bring innovations to market – i.e. probability of export market success<br> • Lack of branded consumer goods suppliers apart from mobile handsets – e.g. Nokia
|2005
+
 
|叶明伟
+
 
|-
 
|-
|[http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=CN1772139&F=0 CN1772139]
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Opportunities '''</center>
|2005
+
| style="background-color:#4F81BD;padding:0.079cm;"| <center>'''Threats '''</center>
|王亚杰
+
 
 
|-
 
|-
|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN03139861.8&leixin=fmzl&title=一种可用于治疗脱发、白发的天然中草药提取组合物及应用&ipc=A61K35/78 CN1569080]
+
| style="background-color:#DCE6F1;padding:0.079cm;"| • Possible renaissance in manufacturing at low-cost<br>• Use of IPR – with mitigations through agreements <br>• Expansion in base materials supply and process equipment manufacture for low temperatures
|2003
+
| style="background-color:#DCE6F1;padding:0.079cm;"| • Older technologies – TFT-LCDs which improve technically – become cheaper, flexible, lower power demands and better colour/contrast, scale up larger, etc, make existing (LCD) players far stronger <br>• Strong competitive position and behaviour of current major players globally and market make market entry difficult or increasingly impossible
|谈汝标
+
 
 +
|}
 +
==Market Forecast==
 +
'''OLED Lighting Market Forecast'''
 +
*OLED lighting will pick up in 2011, and reach $6.3B by 2018.
 +
*The OLED lighting market will reach $1.5B by 2015, and $6.3B by 2018.
 +
*Large investments have been made in OLED lighting in the EU, US, Japan and Korea.
 +
*There are about 20 OLED lighting organizations worldwide. Europe is currently the leading participant in OLED lighting in terms of projects numbers, government funding, and participating companies.
 +
*Over 100 companies and universities are currently working on OLED lighting.
 +
 
 +
[[Image:markets.png|thumb|center|700 px|[[Media:market.pdf|OLED Lighting Market Forecast]]]]
 +
'''OLED TV Market Forecast'''
 +
*OLED TV sets will account for around half of all revenue for OLED panels in 2012, growing rapidly from just $150 million in 2011 to $1.5 billion in 2013.
 +
*iSuppli’s similarly forecasts the global OLED TV market will reach 2.8 million units by 2013, managing a compound annual growth rate (CAGR) of 212.3% from just 3,000 units in 2007.
 +
*In terms of global revenue, OLED TV will hit $1.4 billion by 2013, increasing at a CAGR of 206.8% from $2 million in 2007.
 +
 
 +
[[Image:marketes.png|thumb|center|700 px|[[Media:markets1.pdf|OLED TV Market Forecast]]]]
 +
 
 +
'''OLED Dispaly Market Forecast'''
 +
*OLED display market will grow to $5.5 billion by 2015, from $0.6 billion in 2008, with a CAGR of 37%. Currently, this growth is being driven by the adoption of active matrix OLED (AMOLED) displays for the primary display in mobile phones and portable media players.
 +
 
 +
[[Image:marketees.png|thumb|center|700 px|[[Media:market1s.pdf|OLED Display Market Forecast]]]]
 +
 
 +
==Recent Licensing Activities in OLED Segment==
 +
{|border="2" cellspacing="0" cellpadding="4" width="100%" align="center"
 +
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Licensor'''</font>
 +
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Licensee'''</font>
 +
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Date'''</font>
 +
|align = "center" bgcolor = "#4F81BD"|<font color="#FFFFFF">'''Details'''</font>
 
|-
 
|-
|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN02155404.8&leixin=fmzl&title=毛囊激活液&ipc=A61K35/78 CN1506103]
+
|align = "center" bgcolor = "#DCE6F1"|<font color="#0000FF"><u>[http://www.globaloledtech.com/press-releases.html Global OLED Technology LLC]</u></font>
|2002
+
|align = "center" bgcolor = "#DCE6F1"|OLEDWorks
|赵章光
+
|align = "center" bgcolor = "#DCE6F1"|6th Dec 2011
 +
|align = "center" bgcolor = "#DCE6F1"|Under the terms of the royalty-bearing license, OLEDWorks is granted the right to use certain GOT patents in connection with OLEDWorks<nowiki>’</nowiki> commercialization of specified OLED lighting-related products.
 
|-
 
|-
|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN01127395.X&leixin=fmzl&title=一种止脱生发药物及其制备方法&ipc=A61K35/78 CN1403100]
+
|align = "center"|<font color="#0000FF"><u>[http://www.ledsmagazine.com/news/8/2/7 Universal Display]</u></font>
|2001
+
|align = "center"|Moser Baer
|范希田
+
|align = "center"|8th Feb 2011
 +
|align = "center"|Moser Baer agreed to license Universal<nowiki>’</nowiki>s OLED technology and purchase UniversalPHOLED (phosphorescent OLED) materials for white OLED panel manufacturing. The companies have agreed to work together for five years in the development of Moser Baer<nowiki>’</nowiki>s US-based OLED panel manufacturing project.
 
|-
 
|-
|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN96116925.7&leixin=fmzl&title=免洗养发生发香波&ipc=C11D3/48 CN1165181]
+
|align = "center" bgcolor = "#DCE6F1"|<font color="#0000FF"><u>[http://www.reuters.com/article/2011/09/29/idUS217574+29-Sep-2011+BW20110929 Universal Display]</u></font>
|1996
+
|align = "center" bgcolor = "#DCE6F1"|Pioneer Corp
|殷国健
+
|align = "center" bgcolor = "#DCE6F1"|29th Sep 2011
 +
|align = "center" bgcolor = "#DCE6F1"|Pioneer is supposed to use Universal Display<nowiki>’</nowiki>s highly efficient, high-performance UniversalPHOLED® technology and materials for the manufacture and sale of OLED lighting products
 
|-
 
|-
|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN88103853.9&leixin=fmzl&title=一种通络生发香波&ipc=A61K7/06 CN1031022]
+
|align = "center"|<font color="#0000FF"><u>[http://www.bloomberg.com/news/2011-11-02/dupont-may-have-licensed-technology-to-samsung-consultant-says.html DuPont]</u></font>
|1988
+
|align = "center"|Samsung
|天津市轻工业化学研究所
+
|align = "center"|3rd Nov 2011
 +
|align = "center"|Samsung needed new technology for its larger models for televisions and hoped to benefit from DuPont<nowiki>’</nowiki>s recent innovations.
 
|-
 
|-
|Hair matrix activator
+
|}<br clear="all">
|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN02111941.4&leixin=fmzl&title=一种含中西药复方的育发剂&ipc=A61K7/06 CN1463693]
+
 
|2002
+
==Landscape Analysis Of Top-Emmission OLED==
|朱静建
+
 
 +
 
 +
===Competitor Landscape===
 +
====Top Assignee====
 +
[[Image:Assigneenew.png|thumb|center| 1000 px|Top Assignee]]
 +
 
 +
====Filing trends over the publication years====
 +
[[Image:publication12.png|thumb|center| 1000 px|IP activity based on publication years]]
 +
 
 +
====Filing trends over the priority years====
 +
[[Image:priority1.png|thumb|center| 1000 px|IP activity based on priority years]]
 +
 
 +
====Geographical Distribution based on family members====
 +
*The geographical distribution is based on 10 sample patent numbers along with all their family members.  
 +
[[Image:geographical 1.png|thumb|center| 1000 px|Geographical Distribution based on Family members of OLED]]
 +
 
 +
 
 +
 
 +
===Key Inventor Mapping===
 +
{|border="2" cellspacing="0" cellpadding="4" width="100%"
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''S.No'''</center>
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''Inventor'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2000'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2001'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2002'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2003'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2004'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2005'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2006'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2007'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2008'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2009'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''2010'''
 +
| colspan="2"  style="background-color:#99ccff;padding:0.079cm;"| '''Total Result'''
 +
 
 
|-
 
|-
|Anti-androgen <nowiki>+</nowiki> Vasodilator
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''1'''</center>
|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN96109964.X&leixin=fmzl&title=一种治疗脂溢性脱发的高效低副作用外用药物&ipc=A61K35/78 CN1150043]
+
| style="padding:0.079cm;"| Cok, Ronald
|1996
+
| style="padding:0.079cm;"| <div align="right"></div>
|梅晓春
+
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">3</div>
 +
| style="padding:0.079cm;"| <div align="right">22</div>
 +
| style="padding:0.079cm;"| <div align="right">18</div>
 +
| style="padding:0.079cm;"| <div align="right">17</div>
 +
| style="padding:0.079cm;"| <div align="right">14</div>
 +
| style="padding:0.079cm;"| <div align="right">15</div>
 +
| style="padding:0.079cm;"| <div align="right">4</div>
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''96'''</div>
 +
 
 
|-
 
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''2'''</center>
 +
| style="padding:0.079cm;"| Park, Jin Woo
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">18</div>
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''20'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''3'''</center>
 +
| style="padding:0.079cm;"| Choi, Beohm Rock
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">6</div>
 +
| style="padding:0.079cm;"| <div align="right">7</div>
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''16'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''4'''</center>
 +
| style="padding:0.079cm;"| Kim, Nam Deog
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">7</div>
 +
| style="padding:0.079cm;"| <div align="right">6</div>
 +
| style="padding:0.079cm;"| <div align="right">3</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''16'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''5'''</center>
 +
| style="padding:0.079cm;"| Tyan, Yuan Sheng
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">7</div>
 +
| style="padding:0.079cm;"| <div align="right">3</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''15'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''6'''</center>
 +
| style="padding:0.079cm;"| Winters, Dustin
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''15'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''7'''</center>
 +
| style="padding:0.079cm;"| Choi, Dong Soo
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">13</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''14'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''8'''</center>
 +
| style="padding:0.079cm;"| Choi, Joon Hoo
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">3</div>
 +
| style="padding:0.079cm;"| <div align="right">4</div>
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''14'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''9'''</center>
 +
| style="padding:0.079cm;"| Kwak, Won Kyu
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">9</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''14'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''10'''</center>
 +
| style="padding:0.079cm;"| Miller, Michael
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">4</div>
 +
| style="padding:0.079cm;"| <div align="right">4</div>
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''14'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''11'''</center>
 +
| style="padding:0.079cm;"| Park, Jae Yong
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">8</div>
 +
| style="padding:0.079cm;"| <div align="right">4</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''14'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''12'''</center>
 +
| style="padding:0.079cm;"| Shore, Joel
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"| <div align="right">3</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''14'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''13'''</center>
 +
| style="padding:0.079cm;"| Arnold, Andrew
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">4</div>
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''13'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''14'''</center>
 +
| style="padding:0.079cm;"| Boroson, Michael
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">4</div>
 +
| style="padding:0.079cm;"| <div align="right">3</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">4</div>
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''13'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''15'''</center>
 +
| style="padding:0.079cm;"| Goh, Joon Chul
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">4</div>
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"| <div align="right">3</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''13'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''16'''</center>
 +
| style="padding:0.079cm;"| Tanaka, Masahiro
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"| <div align="right">4</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''13'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''17'''</center>
 +
| style="padding:0.079cm;"| Choong, Vi En
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''12'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''18'''</center>
 +
| style="padding:0.079cm;"| Ghosh, Amalkumar
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">3</div>
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''12'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''19'''</center>
 +
| style="padding:0.079cm;"| Kim, Eun Ah
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">9</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''12'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''20'''</center>
 +
| style="padding:0.079cm;"| Kobayashi Hidekazu
 +
| style="padding:0.079cm;"| <div align="right"></div>
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"|
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">2</div>
 +
| style="padding:0.079cm;"| <div align="right">5</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="padding:0.079cm;"| <div align="right">1</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''12'''</div>
 +
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''21'''</center>
 +
| style="background-color:#99ccff;padding:0.079cm;"| '''Total Result'''
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''2'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''1'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''1'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''6'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''45'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''67'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''72'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''90'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''47'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''18'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''15'''</div>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <div align="right">'''362'''</div>
 +
 
|}
 
|}
  
=== Details of treatment approaches===
+
===Most Cited Patents===
 +
{|border="2" cellspacing="0" cellpadding="4" width="100%"
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''S.No'''</center>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''Publication Number'''</center>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''Assignee/Applicant'''</center>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''Title'''</center>
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''Publication Date'''</center>
 +
| colspan="3"  style="background-color:#99ccff;padding:0.079cm;"| <center>'''Count of Citing Patents'''</center>
  
{|border="2" cellspacing="0" cellpadding="4" width="100%" align="left"
 
|align = "center"|'''Patent number'''
 
|align = "center"|'''Patent title'''
 
|align = "center"|'''Treatment approach'''
 
|align = "center"|'''Composition nature'''
 
|align = "center"|'''Composition'''
 
|align = "center"|'''Composition action'''
 
 
|-
 
|-
|align = "justify"|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN200510107497.8&leixin=fmzl&title=治疗瘀血阻滞型脱发的中草药汤剂及制备方法&ipc=A61K36/804(2006.01)I CN1772105]<br>YE MINGWEI (CN)<br>叶明伟 (2005)
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''1'''</center>
|align = "justify"|Chinese herbal medicine decoction for treating blood stasis obstruction type alopecia and its prepn<br>治疗瘀血阻滞型脱发的中草药汤剂及制备方法
+
| style="padding:0.079cm;"| US6069443A
|align = "justify"|Vasodilators
+
| style="padding:0.079cm;"| Fed Corporation
|align = "justify"|Herbal extract
+
| style="padding:0.079cm;"| Passive matrix OLED display
|align = "justify"|Astragalus root, prepared rhizome of rehmannia, white peony root, angelica, peach kernel and sufflower
+
| style="padding:0.079cm;"| <div align="right">30/05/2000</div>
|align = "justify"|Promote blood circulation
+
| style="padding:0.079cm;"| <center>97</center>
 +
 
 
|-
 
|-
|align = "justify"|[http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=CN1772139&F=0 CN1772139<br>]WANG YAJIE (CN)<br>王亚杰 2005
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''2'''</center>
|align = "justify"|Alopecia areata treating medicine<br>一种治疗斑秃的药物
+
| style="padding:0.079cm;"| US6366017B1
|align = "justify"|Vasodilators
+
| style="padding:0.079cm;"| Agilent Technologies
|align = "justify"|Herbal extract
+
| style="padding:0.079cm;"| Organic light emitting diodes with distributed bragg reflector
|align = "justify"|Pinellia tuber, fleeceflower root, arborvitae seed, chickení s gizzard membrane, prepared rhizome of rehmannia, Poris cocos, Codonopsis pilosula, etc
+
| style="padding:0.079cm;"| <div align="right">02/04/2002</div>
|align = "justify"|Promote blood circulation
+
| style="padding:0.079cm;"| <center>80</center>
 +
 
 
|-
 
|-
|align = "justify"|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN03139861.8&leixin=fmzl&title=一种可用于治疗脱发、白发的天然中草药提取组合物及应用&ipc=A61K35/78 CN1569080]<br>TAN RUBIAO (CN)<br>谈汝标 2003
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''3'''</center>
|align = "justify"|Natural Chinese herb composition for treating alopecia and leucotrichia and its application<br>一种可用于治疗脱发、白发的天然中草药提取组合物及应用
+
| style="padding:0.079cm;"| US20020197511A1
|align = "justify"|Vasodilators
+
| style="padding:0.079cm;"| United Of America As Respresented By The Secretary Of The Air Force
|align = "justify"|Herbal extract
+
| style="padding:0.079cm;"| High efficiency multi-color electro-phosphorescent OLEDS
|align = "justify"|Ginger, Cinnamomum cassia, myrrh, clove, mace nutmeg, Loranthus mulberry mistletoe, rhizoma dioscoreae, ligustrum japonicum, drynaria, fleece-flower root, and black sesame seeds
+
| style="padding:0.079cm;"| <div align="right">26/12/2002</div>
|align = "justify"|Enhances the hair growth and healthier hairs
+
| style="padding:0.079cm;"| <center>51</center>
 +
 
 
|-
 
|-
|align = "justify"|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN02111941.4&leixin=fmzl&title=一种含中西药复方的育发剂&ipc=A61K7/06 CN1463693]<br>朱静建 2002
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''4'''</center>
|Hair growing preparation containing compound of Chinese medicine and Western medicine<br>一种含中西药复方的育发剂
+
| style="padding:0.079cm;"| US6265820B1
|align = "justify"|Hair matrix activator
+
| style="padding:0.079cm;"| Emagin Corporation,De
|Mixture of Herbal extracts and western medicine
+
| style="padding:0.079cm;"| Heat removal system for use in organic light emitting diode displays having high brightness
|align = "justify"|Persimmon leaf, oriental arbor-vitae leaf, ginseng leaf, yellow qi, fruit of the glossy privet, polygonum multiflorum, Kudzu root, dry ginger; Plus:Minoxidil, Vitamins and derivative, cystine, serine, leucine.
+
| style="padding:0.079cm;"| <div align="right">24/07/2001</div>
|align = "justify"|Better and  faster hair growth
+
| style="padding:0.079cm;"| <center>50</center>
 +
 
 
|-
 
|-
|align = "justify"|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN02155404.8&leixin=fmzl&title=毛囊激活液&ipc=A61K35/78 CN1506103]<br>赵章光2002
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''5'''</center>
|align = "justify"|Hair follice activating liquid<br>毛囊激活液
+
| style="padding:0.079cm;"| US20020195968A1
|align = "justify"|Vasodilators
+
| style="padding:0.079cm;"| IBM
|align = "justify"|Herbal extract
+
| style="padding:0.079cm;"| Oled current drive pixel circuit
|align = "justify"|Ginseng, twists the stock blue, the licorice, the Sophora flavescens and hot peppers
+
| style="padding:0.079cm;"| <div align="right">26/12/2002</div>
|align = "justify"|Activates the hair-follicle and enhances the hair growth.
+
| style="padding:0.079cm;"| <center>44</center>
 +
 
 
|-
 
|-
|align = "justify"|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN01127395.X&leixin=fmzl&title=一种止脱生发药物及其制备方法&ipc=A61K35/78 CN1403100]<br>范希田 2001
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''6'''</center>
|align = "justify"|Trichogen and its prepn<br>一种止脱生发药物及其制备方法
+
| style="padding:0.079cm;"| US20020186209A1
|align = "justify"|Vasodilators
+
| style="padding:0.079cm;"| Eastman Kodak Company
|align = "justify"|Herbal extract
+
| style="padding:0.079cm;"| Touch screen for use with an OLED display
|align = "justify"|Ginseng, ganoderma lucidum, Chinese rhubarb, polygonum multiflorum, Chinese prickly ash, ginger, grass seed
+
| style="padding:0.079cm;"| <div align="right">12/12/2002</div>
|align = "justify"|Promote blood circulation and enhance hair growth
+
| style="padding:0.079cm;"| <center>42</center>
 +
 
 
|-
 
|-
|align = "justify"|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN96116925.7&leixin=fmzl&title=免洗养发生发香波&ipc=C11D3/48 CN1165181]<br>殷国健 1996
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''7'''</center>
|Washing free shampoo for nourishing and growing hair<br>免洗养发生发香波
+
| style="padding:0.079cm;"| US20030127973A1
|align = "justify"|Vasodilator
+
| style="padding:0.079cm;"| Universal Display Corporation
|Vitamin composition
+
| style="padding:0.079cm;"| OLEDs having increased external electroluminescence quantum efficiencies
|align = "justify"|Vitamin P (Bioflavonoids), Vitamin B15, Vitamin B2, nicotinic acid, bromo—geramineum
+
| style="padding:0.079cm;"| <div align="right">10/07/2003</div>
|align = "justify"|Stimulate hair growth
+
| style="padding:0.079cm;"| <center>41</center>
 +
 
 
|-
 
|-
|align = "justify"|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN96109964.X&leixin=fmzl&title=一种治疗脂溢性脱发的高效低副作用外用药物&ipc=A61K35/78 CN1150043]<br>梅晓春 1996
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''8'''</center>
|Efficient low-side effect external use medicine for curing seborrheic baldness<br>一种治疗脂溢性脱发的高效低副作用外用药物
+
| style="padding:0.079cm;"| US6844673B1
|align = "justify"|Anti-androgen <nowiki>+</nowiki> Vasodilator
+
| style="padding:0.079cm;"| Alien Technology Corporation
|Mixture of Herbal extracts and organic compounds
+
| style="padding:0.079cm;"| Split-fabrication for light emitting display structures
|align = "justify"|Polygonum multiflorum, Ligustrum lucidum, Morus alba, Rehmannia glutinosa, Eclipta prostrata, Saliva miltiorrhiza, Carthamus tinctorius, Cnidium monnieri, Sophora flavescens, Dictamnus dasycarpus, Kochia scoparia,  and antioxidants
+
| style="padding:0.079cm;"| <div align="right">18/01/2005</div>
|align = "justify"|Inhibit the excess secretion of the sebaceous glands, increase the blood circulation on scalp and enhance the hair growth
+
| style="padding:0.079cm;"| <center>38</center>
 +
 
 
|-
 
|-
|align = "justify"|[http://search.sipo.gov.cn/sipo/zljs/hyjs-yx-new.jsp?recid=CN88103853.9&leixin=fmzl&title=一种通络生发香波&ipc=A61K7/06 CN1031022]<br>天津市轻工业化学研究所 1988
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''9'''</center>
|Channel-stimulating and hair-growing hair shampoo<br>一种通络生发香波
+
| style="padding:0.079cm;"| US20040174116A1
|align = "justify"|Vasodilators
+
| style="padding:0.079cm;"| Universal Display Corporation
|Herbal extract <nowiki>+</nowiki> detergent
+
| style="padding:0.079cm;"| Transparent electrodes
|align = "justify"|<font color="#454545">Herbal extracts, Penetration media, Detergents.</font>
+
| style="padding:0.079cm;"| <div align="right">09/09/2004</div>
|align = "justify"|Increases the blood circulation under the scalp, reduces the hair los
+
| style="padding:0.079cm;"| <center>36</center>
 +
 
 
|-
 
|-
|}<br clear="all">
+
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''10'''</center>
== Conclusions ==
+
| style="padding:0.079cm;"| US20050194896A1
* Hair loss medication is a very active area of research and intellectual property development.
+
| style="padding:0.079cm;"| Hitachi Displays Ltd.
* One of the most promising areas of development is the area of Anti-androgens.
+
| style="padding:0.079cm;"| Light emitting element and display device and illumination device using the light emitting element
* The top companies are Merck, L’Oreal and Smithkline.
+
| style="padding:0.079cm;"| <div align="right">08/09/2005</div>
 +
| style="padding:0.079cm;"| <center>35</center>
 +
 
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''11'''</center>
 +
| style="padding:0.079cm;"| US20020074935A1
 +
| style="padding:0.079cm;"| Universal Display Corporation
 +
| style="padding:0.079cm;"| Highly stable and efficient OLEDs with a phosphorescent-doped mixed layer architecture
 +
| style="padding:0.079cm;"| <div align="right">20/06/2002</div>
 +
| style="padding:0.079cm;"| <center>35</center>
 +
 
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''12'''</center>
 +
| style="padding:0.079cm;"| US20040217702A1
 +
| style="padding:0.079cm;"| Corning Incorporated
 +
| style="padding:0.079cm;"| Light extraction designs for organic light emitting diodes
 +
| style="padding:0.079cm;"| <div align="right">04/11/2004</div>
 +
| style="padding:0.079cm;"| <center>33</center>
 +
 
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''13'''</center>
 +
| style="padding:0.079cm;"| US20020030647A1
 +
| style="padding:0.079cm;"| Universal Display Corporation
 +
| style="padding:0.079cm;"| Uniform active matrix oled displays
 +
| style="padding:0.079cm;"| <div align="right">14/03/2002</div>
 +
| style="padding:0.079cm;"| <center>32</center>
 +
 
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''14'''</center>
 +
| style="padding:0.079cm;"| US20050248270A1
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Encapsulating OLED devices
 +
| style="padding:0.079cm;"| <div align="right">10/11/2005</div>
 +
| style="padding:0.079cm;"| <center>31</center>
 +
 
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''15'''</center>
 +
| style="padding:0.079cm;"| US20040113875A1
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Color oled display with improved power efficiency
 +
| style="padding:0.079cm;"| <div align="right">17/06/2004</div>
 +
| style="padding:0.079cm;"| <center>29</center>
 +
 
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''16'''</center>
 +
| style="padding:0.079cm;"| US20030230972A1
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Oled display having color filters for improving contrast
 +
| style="padding:0.079cm;"| <div align="right">18/12/2003</div>
 +
| style="padding:0.079cm;"| <center>28</center>
 +
 
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''17'''</center>
 +
| style="padding:0.079cm;"| US20050040756A1
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| OLED device having microcavity gamut subpixels and a within gamut subpixel
 +
| style="padding:0.079cm;"| <div align="right">24/02/2005</div>
 +
| style="padding:0.079cm;"| <center>27</center>
 +
 
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''18'''</center>
 +
| style="padding:0.079cm;"| US6670772B1
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Organic light emitting diode display with surface plasmon outcoupling
 +
| style="padding:0.079cm;"| <div align="right">30/12/2003</div>
 +
| style="padding:0.079cm;"| <center>26</center>
 +
 
 +
|-
 +
| style="background-color:#99ccff;padding:0.079cm;"| <center>'''19'''</center>
 +
| style="padding:0.079cm;"| US20040061136A1
 +
| style="padding:0.079cm;"| Eastman Kodak Company
 +
| style="padding:0.079cm;"| Organic light-emitting device having enhanced light extraction efficiency
 +
| style="padding:0.079cm;"| <div align="right">01/04/2004</div>
 +
| style="padding:0.079cm;"| <center>26</center>
 +
 
 +
|}
 +
 
 +
===Most Cited Patents Mapping===
 +
[[Image:most.png|thumb|center| 1000 px|Most Cited Patents]]
 +
 
 +
===Technology Mapping===
 +
* In OLED devices not all internally generated light is coupled out of the device (only 20%-50%), which reduces the device efficiency and lifetime.  
 +
* Modification in structures are applied to improve outcouple efficiency in order to enhance the efficiency and lifetime of top emission OLEDs.
 +
* Below is a snapshot of how various organizations are using different design structures, using the same principle of internal reflection, to achieve higher out-coupling efficiencies.
 +
 
 +
====Comparison of out coupling of waveguiding light in top-emission polyLED stack====
 +
[[Image:Slide-oled.jpg|thumb|center| 500 px|]]
 +
* Some light is reflected out of the OLED at stray angles in typical cases. By using a barrier material (form of microparticles) in the cathode layer, this light at stray angles hits the barrier material, and some of it is reflected back and guided out at the right angles, reducing light loss.
 +
 
 +
[[Image:Slide-oled1.jpg|thumb|center| 500 px|]]
 +
 
 +
* Microparticles are incorporated in the substrate, which prevents light loss by reflecting light emitted at stray angles.
 +
 
 +
[[Image:Slide-oled2.jpg|thumb|center| 500 px|]]
 +
 
 +
* A highly reflective anode is provided made of Aluminium or Silver, with a mirror like finish, to reflect light.
 +
[[Image:Slide-oled3.jpg|thumb|center| 500 px|]]
 +
 
 +
* A shielding layer is provided below the anode, across its entire surface, thus increasing the surface area from which light can be reflected outside.
 +
 
 +
[[Image:Slide-oled4.jpg|thumb|center| 500 px|]]
 +
 
 +
* The reflective layer, anode, is made of a highly reflective surface like Aluminium alloy or silver.
 +
 
 +
====Conclusion====
 +
The innovation is towards:
 +
* Incorporating micro-particles structure over the substrate that provide a reflective surface.
 +
* Highly reflective materials using metals like Molybdenum etc.
 +
 
 +
 
 +
 
 +
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! style="background:lightgrey" | Samir Raiyani

Latest revision as of 08:02, 27 July 2015

This report presents a brief introduction to OLED (organic light emitting diode) and technologies available for top emission OLED. A detailed taxonomy for OLED is presented covering parts of the type of OLED, material used, manufacturing, applications among others. A detailed landscape analysis of patent and non-patent literature is done with a focus on Top Emission OLED (TEOLED). The product information of major players in the market is also captured for OLED. The final section of the report covers the existing and future market predictions for OLED.

Introduction

  • OLED technology was firstly developed in 1987 at Eastman Kodak Company by Tang and Van Slyke using small-molecule (sm-OLED). In 1990 Richard Friend, Jeremy Burroughes and Donal Bradley discovered electroluminescence capabilities from conjugated polymers so laying down the foundations for a new generation of flat panel displays.
  • The growing number of electronic devices using organic light emitting diode displays shows that after years of promise, the technology is increasingly finding place in many products. But while OLED displays might challenge LCDs as the screens of choice for smaller gadgets, the technology may not become mainstream for notebook PCs or TVs within this decade.
  • OLED displays use organic compounds that emit light when exposed to an electric current. They are brighter, have better contrast, offer wider viewing angles, use less power, and provide faster response times than liquid crystal displays. OLED screens' thickness is a third of that of LCDs, since they don't need a back-light, and that makes them a good fit for portable electronics devices.

Read More?

Click on OLED Background to read more about OLED.

Traditional light bulbs were invented more than 130 years ago. Since then the basic principle of creating light remains the same, although the design has been tweaked.An electric current passing through a tungsten wire causes it to heat up and glow white hot.Today, more than 20% of electricity used in US buildings is eaten up by lights and nearly half that amount is used by traditional, incandescent light bulbs. It has been a long-term goal of scientists to come up with something that would reduce this mammoth energy demand.

The OLEDs do not heat up like today's light bulbs and so are far more energy efficient and last longer.They also produce a light that is more akin to natural daylight than traditional bulbs. The new polymer uses a fluorescent blue material instead which lasts much longer and uses less energy.

Top Emission OLED: Search Strategy

The present study on the IP activity in the area of OLED with focus on Top Emission OLED (TEOLED) is based on a search conducted on Micropat.

Control Patents

S. No.
Patent/Publication No.
Publication Date(mm/dd/yyyy)
Assignee/Applicant
Title
1
US7791271B2
7/9/2010
Global OLED Technology LLC Top-Emitting OLED Device With Light-Scattering Layer and Color-Conversion.
2
US7781961B2
08/24/2010
Novaled AG Top Emitting, Electroluminescent Component With Frequency Conversion Centres.
3
US7002293B2
02/21/2006
Eastman Kodak Company Organic Light Emitting Diode With Improved Light Emission Through The Cathode.
4
US6770502B2
3/8/2004
Eastman Kodak Company Method Of Manufacturing a Top-emitting OLED display Device with Desiccant Structures.
5
US20080169757A1
07/17/2008
TPO Displays Corp. Top-Emitting Organic Electroluminescent Display
6
US20060043373A1
2/3/2006
Industrial Technology Research Institute Method for Manufacturing a Pixel Array of Top Emitting OLED.
7
US20050236629A1
10/27/2005
Samsung Corp. Top Emission Organic Light Emitting Diode Display Using Auxiliary Electrode to Prevent Voltage Drop of Upper Electrode and Method of Fabricating the Same.
8
EP1489671A2
12/22/2004
Global OLED Technology LLC Method of Making a Top-Emitting OLED device having Improved Power Distribution
9
EP1029336A1
08/23/2000
Fed Corp. Top Emitting OLED with Refractory Metal Compounds as Bottom Cathode .
10
WO2001057904A1
9/8/2001
Emagin Corp. Low Absorption Sputter Protection Layer for OLED Structure.

Patent Classes

S. No.
Class No.
Class Type
Definition
1
257/40 USPC Active solid-state devices (e.g., transistors, solid-state diodes) /Organic semiconductor material
2
257/E51.018 USPC Active solid-state devices (e.g., transistors, solid-state diodes) / organic solid state devices, processes or apparatus peculiar to manufacture or treatment of such devices or of parts thereof / structural detail of device / light-emitting organic solid-state device with potential or surface barrier
3
257/E51.019 USPC Active solid-state devices (e.g., transistors, solid-state diodes) / organic solid state devices, processes or apparatus peculiar to manufacture or treatment of such devices or of parts thereof / structural detail of device / light-emitting organic solid-state device with potential or surface barrier / Electrode
4
257/E51.02 USPC Active solid-state devices (e.g., transistors, solid-state diodes) / organic solid state devices, processes or apparatus peculiar to manufacture or treatment of such devices or of parts thereof / structural detail of device / light-emitting organic solid-state device with potential or surface barrier / Electrode / Encapsulation
5
257/E51.021 USPC Active solid-state devices (e.g., transistors, solid-state diodes) / organic solid state devices, processes or apparatus peculiar to manufacture or treatment of such devices or of parts thereof / structural detail of device / light-emitting organic solid-state device with potential or surface barrier / Electrode / Arrangements for extracting light from device (e.g., Bragg reflector pair)
6
257/E51.022 USPC Active solid-state devices (e.g., transistors, solid-state diodes) / organic solid state devices, processes or apparatus peculiar to manufacture or treatment of such devices or of parts thereof / structural detail of device / light-emitting organic solid-state device with potential or surface barrier / Multicolor organic light-emitting device (OLED)
7
313/504 USPC Electric lamp and discharge devices/solid-state type/ with particular phosphor or electrode material / Organic phosphor
8
H01L 27/28 IPC Semiconductor devices; electric solid state devices not otherwise provided for / devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate / including components using organic materials as the active part, or using a combination of organic materials with other materials as the active part
9
H01L 27/32 IPC Semiconductor devices; electric solid state devices not otherwise provided for / devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate / including components using organic materials as the active part, or using a combination of organic materials with other materials as the active part / with components specially adapted for light emission, e.g. flat-panel displays using organic light-emitting diodes
10
H01L 51/50 IPC Semiconductor devices; electric solid state devices not otherwise provided for / solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof / specially adapted for light emission, e.g. organic light emitting diodes (oled) or polymer light emitting devices (pled)
11
H01L 51/52 IPC Semiconductor devices; electric solid state devices not otherwise provided for / solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof / Details of devices
12
H01L 51/56 IPC Semiconductor devices; electric solid state devices not otherwise provided for/specially adapted for sensing infra-red radiation, light, electromagnetic radiation of shorter wavelength, or corpuscular radiation; specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation / Processes or apparatus specially adapted for the manufacture or treatment of such devices or of parts thereo

Concept Table

S. No. Concept 1 Concept 2
Top emission
Organic Light Emitting Diode
1
top emitting oled
2
top emissive polymer led
3
top emission light emitting polymer diode
4
toled organic led
5
teoled organic electroluminescent diode
6
foled
7
sm-oled
8
small molecule oled
9
amoled
10
pmoled

Micropatent Search Strategy

Database: Micropat
Patent coverage: US, EP, WO, JP, DE, GB, FR
Time line: 1836/01/01 to 2011/02/20

S. No.
Concept
Scope
Search String
No. of Hits
1
Classes - OLED Any Classification H01L005150* OR H01L005152* OR H01L005156 OR H05B003308P OR 257E51.022 63152
2
Classes - Organic Semiconductor Devices Any Classification 313504 OR 257040 OR 257E51.018 OR 257E51.019 OR 257E51.020 OR 257E51.021 OR H01L002728 OR H01L002732 27601
3
Top Emission keywords Claims, Title or Abstract ((top emitting) OR (toled) OR (teoled) OR (te-oled) OR (top ADJ2 emitting) OR (top ADJ2 emissive) OR (top ADJ2 emission)) ADJ ((light ADJ emitting ADJ polymer) OR (organic ADJ electro-luminescence ADJ diode) OR (ORganic ADJ electroluminescent ADJ diode) OR (ploymer ADJ light ADJ emitting ADJ diode) OR (ORganic ADJ light ADJ emitting ADJ device) OR (self-luminous ADJ diode) OR (oled) OR (organic led arrays) OR (organic ADJ light ADJ emitting ADJ diode) OR (organic ADJ light ADJ emission ADJ diode) OR (polymer ADJ light ADJ emission ADJ device) OR (organic ADJ electroluminescent device) OR (oel) OR (oleds)) 1141
4
OLED keywords Claims, Title or Abstract ((organic OR (small adj molecule*1) OR polymer*1) adj (lightemitting OR (light adj (emitting OR emission)) OR electroluminescen*2 OR (electro adj luminescen*2))) NEAR3 diode*1) OR oled*2 OR smled*2 OR pled*2 OR (light adj (emitting OR emission) adj polymer*1) OR ((organic OR (small adj molecule*1) OR polymer*1) NEAR3 led*2) 39392
5
Top emissioin OLED keywords Claims, Title or Abstract (((((organic OR (small ADJ molecule*1) OR polymer*1) ADJ (lightemitting OR (light ADJ (emitting OR emission)) OR electroluminescen*2 OR (electro ADJ luminescen*2))) NEAR3 diode*1) OR oled*2 OR smled*2 OR pled*2 OR (light ADJ (emitting OR emission) ADJ polymer*1) OR ((ORganic OR (small ADJ molecule*1) OR polymer*1) NEAR3 led*2)) AND ((top ADJ3 (emissi*2 OR emitting)))) OR (te ADJ oled*2) 429
6
Top Emission keywords AND OLED classes Combined query 1 AND 3 809
7
LED Keywords Claims, Title or Abstract ((lightemitting OR (light ADJ (emitting OR emission)) OR electroluminescen*2 OR (electro ADJ luminescen*2)) NEAR3 diode*1) OR led*2 OR oled*2 OR smled*2 OR pled*2 1617014
8
Top emission keywords AND Organic semiconductor devices classes AND Top emission keywords Combined query 2 AND 7 AND 3 224
9
Top emissioin OLED keywords Full patent spec. (((((organic OR (small ADJ molecule*1) OR polymer*1) ADJ (lightemitting OR (light ADJ (emitting OR emission)) OR electroluminescen*2 OR (electro ADJ luminescen*2))) near3 diode*1) OR oled*2 OR smled*2 OR pled*2 OR (light ADJ (emitting OR emission) ADJ polymer*1) OR ((organic OR (small ADJ molecule*1) OR polymer*1) near3 LED*2)) near3 ((top ADJ3 (emissi*2 OR emitting)))) OR (te ADJ oled*2) 1506
10
German Keywords Full patent spec. ((top adj3 (emissi*2 OR emitting)) OR (Top NEAR2 emittierende*1)) NEAR3 ((organische NEAR2 (led*1 OR Leuchtdiode*1)) OR (Licht adj emittierende adj Polymer*1) OR oled*1) 1430
11
French Keywords Full patent spec. ((top ADJ3 (émissive OR émettant)) OR (démission ADJ top) OR (top ADJ3 (emissi*2 OR emitting))) NEAR3 ((diode*1 NEAR3 électroluminescente NEAR3 organique*1) OR ((Polymère*1 OR organiques) ADJ2 led*1) OR (polymère*1 NEAR3 émettant NEAR3 lumière) OR oled*1) 1412
12
Combined query 5 OR 6 OR 8 OR 9 OR 10 OR 11 2113 (1132 unique)
13
Control Patents Patent/Publication No. WO2001057904A1 OR EP1029336A1 OR EP1489671A2 OR US20050236629A1 OR US20060043373A1 OR US20080169757A1 OR US6770502B2 OR US7002293B2 OR US7781961B2 OR US7791271B2 10
14
Combined query 12 AND 13 10

Scientific Literature Search

S.No
Database
Query
Limits by Date
No.Of Hit
1
Google scholar (Top emitting or top emission or top emissive) and ((organic light emitting diode) or (polymer led) or (light emitting polymer led) or (OLED)) 1990-2011 1840

Search in Japanese database

Database: IPDL (Industrial property digital library), Japan

Date of search: 1900/01/01 to 2011/02/15

S.No.
Issue/Publication date
F-Term Theme
FI/F-term/Facet
Hits
1
1900/01/01 to 2011/03/02 3K107 DD03*[AA01+BB01+BB02+BB03+BB04+BB05+BB06+BB07+BB08+DD01+DD04+DD42+DD50+CC01+CC02+CC04+CC06+CC07+
CC08+CC09+EE02+EE03+EE06+EE22+GG01+GG02+GG03+GG04+GG05+GG06+GG07+GG08+GG08]
1596
  • F-Terms and theme used in search
Japanese F-term search
Definition
Sr. No.
F- Term theme 3K107 Electroluminescent light sources
1
F- Term AA01 Organic electroluminescent element.
2
F- Term BB01 Used in displays.
3
F- Term BB02 Used in Lights or light sources
4
F- Term BB03 Used in Backlights or the like for liquid crystals
5
F- Term BB04 Used in printer heads
6
F- Term BB05 Used in lasers
7
F- Term BB06 Used in designs or advertisements
8
F- Term BB07 Used in timepieces
9
F- Term BB08 Used in on-board use
10
F- Term DD01 Having feature of all direction of light emission.
11
F- Term DD03 Having top emission.
12
F- Term DD04 Having double sided emission.
13
F- Term DD42 Having Organic materials.
14
F- Term DD50 Structured with Light emitting layers
15
F- Term CC01 Having Light emitting layers
16
F- Term CC02 Light emission characteristics were improved.
17
F- Term CC04 Has an effect on brightness.
18
F- Term CC06 Has an effect on efficiency
19
F- Term CC07 Has an effect on colours.
20
F- Term CC08 Has an effect on Colour purity; Colour temperatures; Light emission wavelengths, including UV
21
F- Term CC09 Has colour balance feature
22
F- Term EE02 Has white light emission.
23
F- Term EE03 Display having Passive matrices
24
F- Term EE06 Display having Active matrices
25
F- Term EE22 Display having with RGB picture elements having different areas
26
F- Term GG01 Dispaly having color filters.
27
F- Term GG02 Apparatus for deposition
28
F- Term GG03 Apparatus for dry methods
29
F- Term GG04 Apparatus for chemical vapour deposition
30
F- Term GG05 Apparatus for evaporation
31
F- Term GG06 Apparatus for sputtering
32
F- Term GG07 Apparatus for wet methods
33
F- Term GG08 Apparatus for printing
34
F- Term GG08 Apparatus for Inkjet

Taxonomy

Sample Analysis

Patent Analysis

A sample of 200 patents from the search is analyzed based on the taxonomy. Provided a link below for sample spread sheet analysis for Top Emission OLED.

S.No
Patent/Publication No.
Date of Publication
Assignee / Applicant
Title
Problem
Solution
1
US7692191B2
04/06/2010
Samsung Mobile Display Co., Ltd. Top-emitting organic light emitting device In the conventional top-emitting organic light emitting device, each pixel electrode is designed to have a minimum width, and neighboring pixel electrodes are designed to be widely spaced apart from each other by as much as 17 .mu.m. Therefore, the wide space between the pixel electrodes leaks emitted light, thereby deteriorating the voltage-current characteristics of the thin film transistors i.e., increasing photo-leakage. In this patent the top-emitting organic light emitting device has maximized the width of a pixel electrode , thereby enhancing aperture ratio. Furthermore, the pixel electrode is arranged to overlap all thin film transistors, so that light is prevented from leaking through a space between neighboring pixel electrodes, thereby reducing photo-leakage of the thin film transistor.
2
US7554259B2
06/30/2009
Sanyo Electric Co., Ltd. Light emitting display apparatus having excellent color reproducibility Organic electroluminescence panel obtains white light by synthesizing two lights each having complementary color to the other, and the three primary colors differ in luminous intensity. Therefore it is difficult to set chromaticity of white light to desired level. And even after color-filter transmission, red light and blue light will have stronger luminous intensity than green light. The present invention objective provide a light emitting display apparatus having excellent color reproducibility. Organic light emitting layer that synthesizes two or more complementary colors of light that are complementary to each other thereby producing white light. It has a resonant structure by which a resonant wavelength is set to a predetermined wavelength, and outputs the white light via the resonant structure where the predetermined wavelength substantially coincides with a wavelength corresponding to a primary color whose luminous intensity is uniform.With the stated construction, non-uniformity in luminous intensity among three primary colors is alleviated by means of amplified luminous intensity due to resonance. This will help obtain white light in which the primary colors are balanced well.
3
US7332859B2
02/19/2008
Canon Kabushiki Kaisha Organic luminescence device with anti-reflection layer and organic luminescence device package In organic luminescence device, the transparent electrode is formed by a material of a refractive index higher than that of air or nitrogen, constituting the external environment of the organic luminescence device. Therefore, the light emitted from the light emitting layer is reflected at a light emitting surface of the transparent electrode , namely at the interface between the transparent electrode and the air constituting the external environment in FIG. 1. For this reason, such organic luminescence device has been associated with a low efficiency of light emission to the exterior. The present invention is to provide an organic luminescence device of a high light-emitting efficiency to the exterior and an organic luminescence device of a satisfactory contrast. A case holding the organic luminescence device in an internal holding space, in which a light emitted from the organic luminescence device, is emitted to the exterior through a light emitting side of the case; wherein anti-reflection means is provided on a light-emitting face on the light-emitting side among faces constituting the internal holding space of the case
4
US6885157B1
04/26/2005
Eastman Kodak Company Integrated touch screen and OLED flat-panel display It has the problem of multiple external electrical connections by employing a flat-panel display having a substrate that extends beyond the substrate of the resistive touch screen. The present invention has the advantage that it reduces the costs and improves the reliability and performance of a touch screen that is used with an OLED flat-panel display by integrating cable connections on a single substrate and providing touch screen signal processing on the display substrate.
5
US6069443A
05/30/2000
FED Corporation Passive matrix OLED display The disadvantage of oxygen and moisture penetration into the interior of the organic light emitting device is the potential to form metal oxides at the metal-organic interface. These metal oxide impurities may allow separation of the cathode or anode and the organic in a matrix . This can result in the formation of dark non-emitting spots (i.e., no illumination).Edge shorting between the cathode and anode layers is a current problem affecting most conventional organic light emitting display devices. This edge shorting reduces the illuminating potential of the display devices. The present invention to provide an insulator layer to minimize edge shorts between lines by separating the OLED layer and the electrode elements. It also provides a sealing structure to isolate the OLED layer from moisture and other contaminants.
6
US20110031511A1
02/10/2011
None ORGANIC LIGHT EMITTING DIODE DISPLAY AND METHOD OF MANUFACTURING THE SAME In the organic light emitting layer, as it is easy to transfer energy in an interface between a light emitting layer and a hole transfer layer, a light emitting efficiency and lifetime of the OLED display are reduced because of an energy loss of triplet inside the OLED display. An interface of the light emitting layer can be improved by forming the inorganic oxide layer between the hole transport layer and the light emitting layer. Further, an energy loss of triplet can be prevented, and the emission efficiency and lifetime can be improved.
7
US20070153051A1
07/05/2007
Samsung Electronics Co., Ltd. Manufacturing flat panel displays with inkjet printing systems For manufacture of certain flat panel display devices, such as LCDs or OLED displays, various thin film patterns are formed on panel substrates of the devices, typically using photolithography processes. However, as displays become larger, the amount of material that must be deposited on substrates to form the thin film patterns also becomes larger, inturn increases the manufacturing costs of the panels. Inkjet printing systems have been developed for forming the thin film patterns on the substrates by depositing them on the substrates in the form of special inks. These systems deposit the ink on the substrate through an inkjet head. However, the inkjet head includes a plurality of nozzles, and if only one of these nozzles becomes dysfunctional, the number of passes that the inkjet printing head must make increases. As a result, processing time and costs are substantially increased.
8
US6911671B2
06/28/2005
Eastman Kodak Company Device for depositing patterned layers in OLED displays To achieve color pixelation in OLED imaging panels, fabrication of a multicolor OLED imaging panel using a shadow masking method is used. A multicolor organic electroluminescent ("EL") medium is vapor deposited and patterned by controlling an angular position of a substrate with respect to a deposition vapor stream. The positioning an element in direct contact with a surface of a substrate can invite problems of abrasion, distortion, or partial lifting, this may cause abrasion, distortion, or partial lifting of the first-color pattern. The present invention is that a pattern of vaporized material, such as organic material, can be deposited without the use of shadow mask.Another feature is that a plurality of devices can be used for simultaneously depositing different organic materials. Such organic materials can emit light in different ranges of the spectrum.
9
US7218295B2
05/15/2007
AU Optronics Corp. Driving method for active matrix OLED display In one display frame, the current received by the OLED is fixed.The driving method used previously accumulates carriers inside the OLED which reduce the life of the OLEDs. Moreover, the voltage across the OLED gradually increases over timewhich inturn increases power. This effects the OLED over time. The present invention uses a driving method to neutralize carrier accumulation in the OLED, thereby reducing the increase in voltage and minimizing the increase in power consumption across both ends of the OLED over time, further increasing the life of the OLED.
10
US7067170B2
06/27/2006
Eastman Kodak Company Depositing layers in OLED devices using viscous flow To achieve color pixelation in OLED imaging panels, fabrication of a multicolor OLED imaging panel using a shadow masking method is used. A multicolor organic electroluminescent ("EL") medium is vapor deposited and patterned by controlling an angular position of a substrate with respect to a deposition vapor stream. The positioning an element in direct contact with a surface of a substrate can invite problems of abrasion, distortion, or partial lifting, this may cause abrasion, distortion, or partial lifting of the first-color pattern. The present invention is that the method of color pixelating an organic layer includes providing a plurality of vapor sources disposed outside of a deposition chamber for generating vapors of organic materials, and connecting such vapor sources to a manifold disposed in the chamber. By using vapor deposition method, we can eliminate precision shadow masks.

Click here to view the detailed analysis sheet for doubly-fed induction generators patent analysis.

Article Analysis

S.No.
Title
Authors
Publication date
Journal/Conference
Dolcera summery.
1
Application of Screen Printing in the Fabricationof Organic Light-Emitting Devices Dino A. Pardo, Ghassan E. Jabbour,* andNasser Peyghambarian 01/27/2000 Optical Sciences Center, University of Arizona.IEEE 27 Jan 2000 This article explains the screen printing technique which deposits organic active layer having a thickness of several tens of nanometers and acting as a hole-transport layer (HTL) in multilayer OLEDs. The resulting devices emitlight at low voltage (<5 V) and have a peak external quantum efficiency of 0.91 %.
2
Multicolor Organic Light-Emitting DiodesProcessed by Hybrid Inkjet Printing Shun-Chi Chang, Jie Liu, Jayesh Bharathan,Yang Yang,* Jun Onohara and Junji Kido 08/07/1999 Department of Materials Science and EngineeringUniversity of California at Los Angeles. willey 8 Jul 1999 This article presents a multicolor patterning technique to produce controllable patterning of red-green-blue OLEDs with fine pixel displays. The LEDs comprise bilayer structures of red and green dopants with inkjet-printed onto a film of the blue-emitting semiconducting polymer, the latter serving as the hole-transport layer.
3
Organic light-emitting diode (OLED)technology: materials, devices and displaytechnologies Bernard Geffroy, Philippe le Roy and Christophe Prat 06/02/2006 Laboratoire Cellules et Composants. willey 6 Feb 2006 This article presents an overview of OLED's over LCD's. OLED'S have a thickness, currently less than 2 mm. Having high contrast ratio is also a strong point of OLED and also in fast response time.OLEDs for flat-panel display applications are their self-emitting property, high luminous efficiency, full-colour capability, wide viewing angle, high contrast,low power consumption, low weight, potentially large area colour displays and flexibility.
4
Organic/polymeric electroluminescent devices processed by hybrid ink-jet printing Yang Yang, Shun-Chi Chang, Jayesh Bharathan and Jie Liu 04/05/1999 Journal of Materials Science: Materials in Electronics Volume 11, Number 2, The HIJP concept is a unique approach for fabricating polymer and organic electronic devices. One is able to apply this technology for the deposition of various functional materials such as charge-injection layers, charge-blocking layers, and multicolor polymer/organic emissive layers. It can be used for the fabrication of logos, indicator lights, multicolor displays and also in bio-medical applications such as biosensors for low cost diagnostics.
5
White Organic Light-Emitting Devices for Solid-State Lighting B. W. D'Andrade, S. R. Forrest 14/10/2004 Department of Electrical Engineering, Princeton University Willey 14 OCT 2004 This article presents the WOLEDs increasing display applications for use primarily as liquid-crystal display backlights. They have achieved high material purity, low cost, high brightness,color quality and long operational life-times.
6
White organic light-emitting diodes with fluorescent tube efficiency Sebastian Reineke, Frank Lindner, Gregor Schwartz, Nico Seidler, Karsten Walzer 14/05/2009 Institute of Applied Photophysics. Vol 459 Macmillan Pub This article presents an WOLED havinh high internal quantum efficiencies for the con-version of electrical energy to light have been realized by focussing on reducing energetic and ohmic losses that occur during electron–photon conversion.This can be achieved by improved OLED structure which reaches fluorescent tube efficiency. By combining a care-fully chosen emitter layer with high-refractive-index substrates and using a periodic outcoupling structure
7
Precision ink jet printing of polymer light emitting displays J. F. Dijksman, P. C. Duineveld, M. J. J. Hack, A. Pierik, J. Rensen, J.-E. Rubingh, I. Schram andM. M. Vernhou 09/11/2006 Philips Research Laboratories RSC Precision ink jet printing of organic polymer light emitting diodes relies strongly on the accuracy of the droplet generation process.Image capturing using one image at a time for image processing delivers sharper images and can be used for optically measuring droplet volumes.
8
High-efficiency microcavity top-emitting organic light-emittingdiodes using silver anode Huajun Peng, Jiaxin Sun, Xiuling Zhu, Xiaoming Yu, Man Wong, and Hoi-Sing Kwok 17/02/2006 Hong Kong Universityof Science and Technology. AIP High efficient top-emitting OLEDs have been fabricated using highly reflective Ag as the anode. Surfacemodification of the Ag anode by CF4 plasma substantially enhances the hole injection efficiency. The color variation isalmost eliminated in the TOLED. The optimized microcav- ity TOLED has a current efficiency enhancement of 65% and a total outcoupling efficiency enhancement of 35%, as compared with a conventional OLED.
9
Inverted top-emitting organic light-emitting diodes using transparent conductive NiO electrode Se-W. Park, Jeong-M. Choi, Eugene Kim and Seongil Im 09/01/2005 Institute of Physics and Applied Physics, Applied Surface Science 244 (2005) 439–443 TE-OLED device uses a thermally evaporated and semi-transparent NiO film as a top-electrode. Since the sheet resistance of our NiO was very high and its transmittance was only about 50%, the resulting luminance and injection current of our TE-OLED were much inferior to those of the BE-OLED device.
10
Self-assembled monolayer-modified Ag anode for top-emitting polymerlight-emitting diodes Lai-Wan Chong, Yuh-Lang Lee,a͒ and Ten-Chin Wenb͒ 07/12/2006 Department of Chemical Engineering, National Cheng Kung University Self-assembled monolayer is a method to modify the Ag anodes for application in T-PLED. The Ag electrode can be utilized as an effective anode to improve the emitting characteristic of a T-PLED. The Ag anode enhances the hole injection, reduce the op-eration voltage, and significantly increase the current inten-sity and luminous efficiency of the device, without decreasing the reflectivity of the Ag anode.

Click here to view the detailed analysis sheet for Top Emission OLED for non patent literature

Top Cited Patents

S. No.
Patent/Publication No.
Publication Date (mm/dd/yyyy)
Assignee/Applicant
Title
Citation Count
1
US6096496A
8/1/2000
Frankel; Robert D Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis
130
2
US6069443A
5/30/2000
Fed Corporation Passive matrix OLED display
97
3
US6366017B1
4/2/2002
Agilent Technologies Organic light emitting diodes with distributed bragg reflector
80
4
US20020197511A1
12/26/2002
United Of America As Respresented By The Secretary Of The Air Force High efficiency multi-color electro-phosphorescent OLEDS
51
5
US6265820B1
7/24/2001
Emagin Corporation,De Heat removal system for use in organic light emitting diode displays having high brightness
50
6
US20020195968A1
12/26/2002
IBM Oled current drive pixel circuit
44
7
US20020186209A1
12/12/2002
Eastman Kodak Company Touch screen for use with an OLED display
42
8
US20030127973A1
7/10/2003
Universal Display Corporation OLEDs having increased external electroluminescence quantum efficiencies
41
9
US6844673B1
1/18/2005
Alien Technology Corporation Split-fabrication for light emitting display structures
38
10
US20040174116A1
9/9/2004
Universal Display Corporation Transparent electrodes
36
11
US20050194896A1
9/8/2005
Hitachi Displays Ltd. Light emitting element and display device and illumination device using the light emitting element
35
12
US20020074935A1
6/20/2002
Universal Display Corporation Highly stable and efficient OLEDs with a phosphorescent-doped mixed layer architecture
35
13
US20040217702A1
11/4/2004
Corning Incorporated Light extraction designs for organic light emitting diodes
33
14
US20020030647A1
3/14/2002
Universal Display Corporation Uniform active matrix oled displays
32
15
US20050248270A1
11/10/2005
Eastman Kodak Company Encapsulating OLED devices
31
16
US20040113875A1
6/17/2004
Eastman Kodak Company Color oled display with improved power efficiency
29
17
US20030230972A1
12/18/2003
Eastman Kodak Company Oled display having color filters for improving contrast
28
18
US20050040756A1
2/24/2005
Eastman Kodak Company OLED device having microcavity gamut subpixels and a within gamut subpixel
27
19
US6670772B1
12/30/2003
Eastman Kodak Company Organic light emitting diode display with surface plasmon outcoupling
26
20
US20040061136A1
4/1/2004
Eastman Kodak Company Organic light-emitting device having enhanced light extraction efficiency
26

Top Cited Articles

S. No.
Title
Publication Date
Journal/Conference
Citations Count
1
Electroluminescence from single monolayers of nanocrystals in molecular organic devices
Oct 2002
Nature, Internatinal journal of science.
736
2
Spin-dependent exciton formation in π-conjugated compounds
Aug 2001
Nature, Internatinal journal of science.
220
3
Highly Efficient Organic Devices Based on Electrically Doped Transport Layers
Mar 2007
American Chemical Society Pub.
211
4
Phosphorescent top-emitting organic light-emitting devices with improved light outcoupling
Nov 2002
Applied Physics Letters / Volume 82
111
5
Thin-film permeation-barrier technology for flexible organic light-emitting devices
Jan 2004
IEEE Photonics Society
104
6
Design of flat-panel displays based on organic light-emitting devices
Feb 1998
IEEE Photonics Society
100
7
A new a-Si:H thin-film transistor pixel circuit for active-matrix organic light-emitting diodes
Aug 2003
IEEE Electron Devices Society
86
8
The road to high efficiency organic light emitting devices
Sep 2003
ScienceDirect
87
9
Amorphous silicon thin film transistor circuit integration for organic LED displays on glass and plastic
Sep 2004
IEEE Photonics Society
73
10
Transparent-cathode for top-emission organic light-emitting diodes
Feb 2003
Applied Physics Letters
72

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Products

S. No.
Company
Product
Specifications
1
Sony
Oled 2.png
BVME250
Digital Inputs Specifications Detail:
HDMI HDMI (x1) (HDCP correspondence, Deep Color correspondence)
SDI (SMPTE 259M) BNC (x2)
Display Specifications Detail:
Image Aspect Ratio 16:09
Resolution 1920 x 1080 pixels (Full HD)
Screen Size 24 5/8 inches (623.4 mm)
Viewing Angle 89°/89°/89°/89°
General Specifications Specifications Detail:
Dimensions (W x H x D) 22 3/4 x 16 3/4 x 5 7/8 inches
Weight 28 lb 11 oz
Power Requirements Specifications Detail:
Power Consumption Approx. 145 W
Power Requirements AC 100 V to 240 V, 1.6 A to 0.8 A, 50/60 Hz
2
Sony
Oled 3.png
BVM-E170
Digital Inputs Specifications Detail:
HDMI HDMI (x1) (HDCP correspondence, deep colour correspondence)
SDI BNC (x2)
Display Specifications Detail:
Image Aspect Ratio 16:09
Resolution 1920 x 1080 pixels (Full HD)
Screen Size 365.8 x 205.7 mm (14 1/2 x 8 1/8 inches)
Viewing Angle 89°/89°/89°/89° (typical) (up/down/left/right contrast >10:1)
General Specifications Specifications Detail:
Dimensions (W x H x D) 436.0 x 282.4 (266.4)* x 214.7 mm (17 1/4 x 11 1/4 (10 1/2)* x 8 1/2 inches) * Height without legs
Weight 8.5 kg (18 lb 11 oz)
Power Requirements Specifications Detail:
Power Consumption Approx. 65 W normally with input from a standard HDMI input. Approx. 115 W at maximum load, with four option slots in use and maximum luminance compensation for any deterioration due to aging.
Power Requirements AC 100 V to 240 V, 1.4 A to 0.7 A, 50/60 Hz DC 24 V to 28 V, 4.7 A to 4.0 A
3
Sony
Oled 1.png
PVM-740
Digital Inputs Specifications Detail:
HDMI Yes
HDSDI (SMPTE 292M) 3G/SDI/HDSDI
SDI (SMPTE 259M) Included
Display Specifications Detail:
Back Light Technology OLED
Native Aspect Ratio 16:09
Resolution 960 x 540
Screen Size Approx 7.4 inches
Viewing Angle 85°/85°/85°/85° (typical) (up/down/left/right contrast>10:1)
General Specifications Specifications Detail:
Dimensions (W x H x D) 8 7/8 x 7 1/4 x 6 3/8 inches Approx. 222.4 x 183.5 x 161.8 mm
On-Screen Display Yes
Rack Mount MB531
Weight Approx. 5 lb 12 oz Approx. 2.6 kg
Power Requirements Specifications Detail:
Power Consumption Max. approx. 27W
Power Requirements AC 100 to 240 V 50/60 Hz 0.5A to 0.3A DC 12 V 1.9 A Rechargeable Battery Pack

Market Research

Major Players

Major types of player
USA
EU
Japan
Korea
Taiwan
China
Original IPR for devices and for manufacture process + material supply / verification
UDC; Kodak; Add-Vision; Magin; Plextronics; Organic Lighting Technologies; GE;3M Innovation CDT (Sumitomo Chemical) (UK); Novaled (G); Fraunhofer IPMS (G); OLED-T (UK); OTB (ND); MicroEmissive Displays (UK) Seiko-Epson; Matsushita; Sony; Sumitomo Chemical; Sharp; TM Display; Konica –Minolta; Sanyo; Toppoly; Lumiotec; Canon; Toshiba Samsung; LG Phillips LCD; Neo View; Doosan DND AU Optoelectronics (AUO); Univision; Toppoly; Tetrahedron; Chi Mei Optoelectronics
Bulk materials and glass suppliers
PPG; 3M; Dow Corning Merck Materials (G); BASF (G); CDT (UK); Degussa/ Evonik (G); HC Starck (G); Sensient Imaging Technologies (G); Goodfellow Metals (UK); Novaled (G) Sumitomo Chemical; Mitsubishi Chemical Syndychem (Shenyang Syndy Chemistry Institute)
Components – driver ccts., packaging etc
Corning; Rockwell Collins ST Microelectronics (It, Fr); Infineon (G) Maekawa; Matsushita; Toppoly Dae Joo Electrncs AUO; Richtek Technologies; Lightsonic; Univision; Wintek Innocom Technologies Shenzen; RIT Display
OEM OLED FPD screen manufacturer & resellers
eMagin; US Micro Products Densitron Technologies (UK); MicroEmissive Displays (MED) (UK); Pacer International Distributors (UK reseller) Seiko-Epson; Sharp; Sumitomo Chemical; Lumiotec; TMDisplay; Sanyo Samsung SDI; Orion OLED; NeoView KOLON; Hyundai LCD AUO; Chi Mei EL (CMEL); Univision Technology; Evervision Electronics; RiTDisplay; TPO Display Visionix; Smartdisplays; Universal Display Technologoes (Jilin); Varitronix (HK); Blaze Display Technologies
Branded application device or/and FPD screen manufacturer with retail device sales
OSD Nokia; Sony-Ericsson Sony; Matsushita; Hitachi; Toshiba; Imase Samsung; LG Philips
OLED lighting branded suppliers and R&D
GE Thorn EMI (UK); OSRAM (G); Siemens (G) Sumitomo Chemica

source: Major players

SWOT analysis

Strengths
Weaknesses
• Capability for innovation
• Production of base materials for OLED manufacture
• Process equipment manufacture is easy.
• Lack of industrial productive capacity or eco-system to support low-cost volume production
• Capability to bring innovations to market – i.e. probability of export market success
• Lack of branded consumer goods suppliers apart from mobile handsets – e.g. Nokia
Opportunities
Threats
• Possible renaissance in manufacturing at low-cost
• Use of IPR – with mitigations through agreements
• Expansion in base materials supply and process equipment manufacture for low temperatures
• Older technologies – TFT-LCDs which improve technically – become cheaper, flexible, lower power demands and better colour/contrast, scale up larger, etc, make existing (LCD) players far stronger
• Strong competitive position and behaviour of current major players globally and market make market entry difficult or increasingly impossible

Market Forecast

OLED Lighting Market Forecast

  • OLED lighting will pick up in 2011, and reach $6.3B by 2018.
  • The OLED lighting market will reach $1.5B by 2015, and $6.3B by 2018.
  • Large investments have been made in OLED lighting in the EU, US, Japan and Korea.
  • There are about 20 OLED lighting organizations worldwide. Europe is currently the leading participant in OLED lighting in terms of projects numbers, government funding, and participating companies.
  • Over 100 companies and universities are currently working on OLED lighting.

OLED TV Market Forecast

  • OLED TV sets will account for around half of all revenue for OLED panels in 2012, growing rapidly from just $150 million in 2011 to $1.5 billion in 2013.
  • iSuppli’s similarly forecasts the global OLED TV market will reach 2.8 million units by 2013, managing a compound annual growth rate (CAGR) of 212.3% from just 3,000 units in 2007.
  • In terms of global revenue, OLED TV will hit $1.4 billion by 2013, increasing at a CAGR of 206.8% from $2 million in 2007.

OLED Dispaly Market Forecast

  • OLED display market will grow to $5.5 billion by 2015, from $0.6 billion in 2008, with a CAGR of 37%. Currently, this growth is being driven by the adoption of active matrix OLED (AMOLED) displays for the primary display in mobile phones and portable media players.

Recent Licensing Activities in OLED Segment

Licensor Licensee Date Details
Global OLED Technology LLC OLEDWorks 6th Dec 2011 Under the terms of the royalty-bearing license, OLEDWorks is granted the right to use certain GOT patents in connection with OLEDWorks commercialization of specified OLED lighting-related products.
Universal Display Moser Baer 8th Feb 2011 Moser Baer agreed to license Universals OLED technology and purchase UniversalPHOLED (phosphorescent OLED) materials for white OLED panel manufacturing. The companies have agreed to work together for five years in the development of Moser Baers US-based OLED panel manufacturing project.
Universal Display Pioneer Corp 29th Sep 2011 Pioneer is supposed to use Universal Displays highly efficient, high-performance UniversalPHOLED® technology and materials for the manufacture and sale of OLED lighting products
DuPont Samsung 3rd Nov 2011 Samsung needed new technology for its larger models for televisions and hoped to benefit from DuPonts recent innovations.

Landscape Analysis Of Top-Emmission OLED

Competitor Landscape

Top Assignee

Top Assignee

Filing trends over the publication years

IP activity based on publication years

Filing trends over the priority years

IP activity based on priority years

Geographical Distribution based on family members

  • The geographical distribution is based on 10 sample patent numbers along with all their family members.
Geographical Distribution based on Family members of OLED


Key Inventor Mapping

S.No
Inventor 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 Total Result
1
Cok, Ronald
1
3
22
18
17
14
15
4
2
96
2
Park, Jin Woo
18
2
20
3
Choi, Beohm Rock
1
6
7
2
16
4
Kim, Nam Deog
7
6
3
16
5
Tyan, Yuan Sheng
2
7
3
1
1
1
15
6
Winters, Dustin
2
5
5
2
1
15
7
Choi, Dong Soo
13
1
14
8
Choi, Joon Hoo
2
3
4
5
14
9
Kwak, Won Kyu
1
1
9
1
1
1
14
10
Miller, Michael
4
4
2
1
1
1
1
14
11
Park, Jae Yong
2
8
4
14
12
Shore, Joel
2
2
5
3
1
1
14
13
Arnold, Andrew
4
5
1
1
1
1
13
14
Boroson, Michael
1
4
3
1
4
13
15
Goh, Joon Chul
1
4
5
3
13
16
Tanaka, Masahiro
1
1
1
5
4
1
13
17
Choong, Vi En
5
5
2
12
18
Ghosh, Amalkumar
2
1
1
3
5
12
19
Kim, Eun Ah
1
2
9
12
20
Kobayashi Hidekazu
1
2
2
5
1
1
12
21
Total Result
2
1
1
6
45
67
72
90
47
18
15
362

Most Cited Patents

S.No
Publication Number
Assignee/Applicant
Title
Publication Date
Count of Citing Patents
1
US6069443A Fed Corporation Passive matrix OLED display
30/05/2000
97
2
US6366017B1 Agilent Technologies Organic light emitting diodes with distributed bragg reflector
02/04/2002
80
3
US20020197511A1 United Of America As Respresented By The Secretary Of The Air Force High efficiency multi-color electro-phosphorescent OLEDS
26/12/2002
51
4
US6265820B1 Emagin Corporation,De Heat removal system for use in organic light emitting diode displays having high brightness
24/07/2001
50
5
US20020195968A1 IBM Oled current drive pixel circuit
26/12/2002
44
6
US20020186209A1 Eastman Kodak Company Touch screen for use with an OLED display
12/12/2002
42
7
US20030127973A1 Universal Display Corporation OLEDs having increased external electroluminescence quantum efficiencies
10/07/2003
41
8
US6844673B1 Alien Technology Corporation Split-fabrication for light emitting display structures
18/01/2005
38
9
US20040174116A1 Universal Display Corporation Transparent electrodes
09/09/2004
36
10
US20050194896A1 Hitachi Displays Ltd. Light emitting element and display device and illumination device using the light emitting element
08/09/2005
35
11
US20020074935A1 Universal Display Corporation Highly stable and efficient OLEDs with a phosphorescent-doped mixed layer architecture
20/06/2002
35
12
US20040217702A1 Corning Incorporated Light extraction designs for organic light emitting diodes
04/11/2004
33
13
US20020030647A1 Universal Display Corporation Uniform active matrix oled displays
14/03/2002
32
14
US20050248270A1 Eastman Kodak Company Encapsulating OLED devices
10/11/2005
31
15
US20040113875A1 Eastman Kodak Company Color oled display with improved power efficiency
17/06/2004
29
16
US20030230972A1 Eastman Kodak Company Oled display having color filters for improving contrast
18/12/2003
28
17
US20050040756A1 Eastman Kodak Company OLED device having microcavity gamut subpixels and a within gamut subpixel
24/02/2005
27
18
US6670772B1 Eastman Kodak Company Organic light emitting diode display with surface plasmon outcoupling
30/12/2003
26
19
US20040061136A1 Eastman Kodak Company Organic light-emitting device having enhanced light extraction efficiency
01/04/2004
26

Most Cited Patents Mapping

Most Cited Patents

Technology Mapping

  • In OLED devices not all internally generated light is coupled out of the device (only 20%-50%), which reduces the device efficiency and lifetime.
  • Modification in structures are applied to improve outcouple efficiency in order to enhance the efficiency and lifetime of top emission OLEDs.
  • Below is a snapshot of how various organizations are using different design structures, using the same principle of internal reflection, to achieve higher out-coupling efficiencies.

Comparison of out coupling of waveguiding light in top-emission polyLED stack

Slide-oled.jpg
  • Some light is reflected out of the OLED at stray angles in typical cases. By using a barrier material (form of microparticles) in the cathode layer, this light at stray angles hits the barrier material, and some of it is reflected back and guided out at the right angles, reducing light loss.
Slide-oled1.jpg
  • Microparticles are incorporated in the substrate, which prevents light loss by reflecting light emitted at stray angles.
Slide-oled2.jpg
  • A highly reflective anode is provided made of Aluminium or Silver, with a mirror like finish, to reflect light.
Slide-oled3.jpg
  • A shielding layer is provided below the anode, across its entire surface, thus increasing the surface area from which light can be reflected outside.
Slide-oled4.jpg
  • The reflective layer, anode, is made of a highly reflective surface like Aluminium alloy or silver.

Conclusion

The innovation is towards:

  • Incorporating micro-particles structure over the substrate that provide a reflective surface.
  • Highly reflective materials using metals like Molybdenum etc.


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