Changes

Drug Metabolism

1,577 bytes removed, 20:30, 22 November 2009
/* Sample Report */
[http://books.google.co.in/books?id=eYJXj59Cg_UC&pg=PT51&lpg=PT51&dq=preclinical+drug+metabolism+database&source=bl&ots=75HigyNNky&sig=VDNW182OYEleEr0iLQKgtOrww4I&hl=en&ei=yAEAS4P7KIyGkQWl9fiDDA&sa=X&oi=book_result&ct=result&resnum=3&ved=0CBsQ6AEwAg#v=onepage&q=preclinical%20drug%20metabolism%20database&f=false Source]
==Sample ReportExample==
{|border="2" cellspacing="0" cellpadding="4" width="100%"|align = "center" bgcolor = "#FCD5B4"|'''S.No.'''|align = "center" bgcolor = "#FCD5B4"|'''Database'''|align = "center" bgcolor = "#FCD5B4"|'''Search by'''|align = "center" bgcolor = "#FCD5B4"|'''Phase'''|align = "center" bgcolor = "#FCD5B4"|'''Type Preclinical drug metabolism and pharmacokinetic evaluation of reaction'''|align GW844520= "center" bgcolor = "#FCD5B4"|'''Sub Type'''|align = "center" bgcolor = "#FCD5B4"|'''Sub sub Type'''|align = "center" bgcolor = "#FCD5B4"|'''Product'''|GW844520, a non-|align = "center" bgcolor = "#FCD5B4"|'''1'''|align = "center" rowspan = "3"|<font color="#0000FF"><u>[http://www.drugmetabolism.co.uk/ReactionSelector2.aspx Drug Metabolism]</u></font>|align = "center"|Reaction Type|align = "center"|Phase Ichiral 4(Functionalisation reactions1H)|align = "center"|Oxidation|align = "center"|Carbon Oxidation|align = "center"|Aromatics|align = "center"|Diclofenac to 3<nowiki>’</nowiki>-hydroxy diclofenacpyridone derivative, is a potent, selective inhibitor of Plasmodium mitochondrial function blocking the electron transport chain machinery. The site of action of this class of compounds is cytochrome b, a critical element of the respiratory complex III or bc1 complex.|-|align = "center" bgcolor = "#FCD5B4"|'''2'''|align = "center"|Functional Group - Alcohol|align = "center"|Phase I(Functionalisation reactions)|align = "center"| |align = "center"| |align = "center"| |align = "center"|Ethanol to Acetaldehyde|-|align = "center" bgcolor = "#FCD5B4"|'''3'''|align = "center"|Substrate - Phenytoin|align = "center"|Phase I(Functionalisation reactions)|align = "center"| |align = "center"| |align = "center"| |align = "center"|Phenytoin to (S)-hydroxy-phenytoin|-|align = "center" bgcolor = "#FCD5B4"|'''4'''|align = "center" rowspan = "2"|<font color="#0000FF"><u>[http[Image://umbbdstruc.msi.umn.edu/ University of Minnesota Biocatalysis/Biodegradation database]</u></font>jpg|align = "center" rowspan = "2"|Pathway- Benzonitrilethumb| | | | |align = "center"|<font color="#0000FF">[http://umbbd.msi.umn.edu/bzn/bzn_map.html Click here for Pathway]</font>|-|align = "center" bgcolor = "#FCD5B4"300px|'''5Chemical Structure of GW844520'''| | | | |align = "center"|<font color="#0000FF">[http://umbbd.msi.umn.edu/bzn/bzn_image_map.html Click here for Pathway (Graphic 5K format)]</font>|-|}]
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