Changes
==Patent Infringement Search for the Generic compound==
[[Image:xxx.jpg|thumb|center|800px]]
=Exact match structures=
==Structure-1 (12(doc1))==
===[http://v3.espacenet.com/publicationDetails/claims?CC=DE&NR=4124942A1&KC=A1&FT=D&date=19930128&DB=EPODOC&locale=en_EP DE4124942]===
[[Image:a5.jpg|thumb|center|400px]]
[[Image:a6.jpg|thumb|center|400px]]
*X<sub>1</sub> = A-B-C- C(sp2 carbon), X<sub>2</sub> = F-C-D-C(sp2 carbon), X<sub>3</sub> = R<sub>1</sub>-N<nowiki><</nowiki>, X<sub>4</sub> = N, X<sub>5</sub> = R<sub>2</sub>-C(sp2 carbon)
#X<sub>1</sub>: A =H , B = bond, C = (b) under B which is halo substituted phenylene which completely matches with 4<sup>th</sup> position substituent of the generic compound
#X<sub>2</sub>: D = (b) under B is a phenylene(implies a substituted aryl) and F-C- is a substituent on D. It is clear that this will match with R<sup>2 </sup>(substituent aryl) at the 5<sup>th</sup> position of pyrazole of the generic structure
#X<sub>3</sub>: R<sub>1</sub> = Q(alkyl) which matches with R<sup>1</sup>(alkyl) at the 1<sup>st</sup> position of pyrazole of the generic structure
#X<sub>4</sub>: N which matches with the 2<sup>nd</sup> position of pyrazole of the generic compound
#X<sub>5</sub>: R<sub>2</sub> = Cl, Br which matches with R<sup>3</sup>(halogen) at the 3<sub></sub><sub></sub><sup> rd </sup>position of pyrazole of the generic structure
==Structure-2 (9(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?CC=WO&NR=2007081019A1&KC=A1&FT=D&date=20070719&DB=EPODOC&locale=en_EP WO2007081019]===
[[Image:C1.jpg|thumb|right|700px]]
[[Image:C2.jpg|thumb|center|700px]]
In the above phenyl ring Q is pyrazole.
*<nowiki></nowiki>R<sup>2</sup>= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic compound.
*<nowiki></nowiki>R<sup>4</sup> is halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>4<sup>th</sup> position of above pyrazole is trihalo substituted aryl which matches with substituent at 4<sup>th</sup> position of pyrazole of generic compound .
*<nowiki></nowiki>5<sup>th</sup> position of pyrazole ring is above substituted aryl which matches with R<sup>2</sup>(substituted aryl) at the 5<sup>th</sup> position of pyrazole of generic compound.
==Structure-3 (125(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=19990518&NR=11130754A&DB=EPODOC&locale=en_EP&CC=JP&FT=D JP11130754]===
[[Image:H.jpg|thumb|center|500px]]
Consider left side ring the pyrazole ring
*<nowiki></nowiki>R<sub>1</sub> is 1-4C alkyl which is matching with substituent R<sup>1</sup>(first position) of the generic structure
*<nowiki></nowiki>X is Cl so it is matching with the substituent R<sup>3 </sup>(second position) of the generic structure
*<nowiki></nowiki>R<sub>2</sub> is phenyl substituted by halo, 1-4C alkyl, cyano which is matching with the fourth position of the generic structure
*<nowiki></nowiki>In the fifth position pyrazole(heteroaryl) is there…which is matching with the substituent R<sup>2</sup>(fifth position) of the generic structure.
==Structure-4 (109(doc2))==
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=2006078610A1&KC=A1&FT=D&date=20060727&DB=EPODOC&locale=en_EP WO2006078610]===
[[Image:J.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sub>2</sub> is 1-6C alkyl which is matching with substituent R<sup>1</sup>(first position) of the generic structure
*<nowiki></nowiki>R<sub>4</sub> is halo matching with the substituent R<sup>3</sup> (second position) of the generic structure
*<nowiki></nowiki>R<sub>3</sub> is heteroaryl or phenyl substituted by 1-8C alkyl, halo, CN, 1-6C alkoxy which is matching with the fourth position of the generic structure
*<nowiki></nowiki>In fifth position substituted aryl ring there, which is matching with the substituent R<sup>2</sup>(fifth position) of the generic structure.
==Structure-5 (128(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=19981027&NR=5827602A&DB=EPODOC&locale=en_EP&CC=US&FT=D US5827602]===
[[Image:a20.jpg|thumb|center|500px]]
*R<sub>1</sub>-R<sub>6</sub>=H, F, 1-4C alkyl, phenyl
*R<sub>2</sub>= 1-4C alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*R<sub>5</sub>= F which matches with R<sup>3</sup>(halo)at 1<sup>st</sup> position of pyrazole of the generic structure
*R<sub>4</sub>= phenyl substituted with an electron with drawing group matches with substituent at 4<sup>th</sup> position of pyrazole of generic structure
*R<sub>3</sub>= substituted aryl which matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of the generic structure
==Structure-6 (19(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=US2007100181&ST=number&compact=false&DB=EPODOC US 2007100181]===
[[Image:b3.jpg|thumb|center|500px]]
R<sub>1</sub>-R<sub>2</sub>= H, -C<sub>2</sub>H<sub>5 </sub>which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>3</sub>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>4</sub>= 6-25C heteroaryl having 1-3 heteroatoms(N)(could be pyridine) with substituents as halo, OH and alkyl which completely resembles substituent at 4<sup>th</sup> position of pyrazole of the generic structure
R<sub>5</sub>= 6-25C heteroaryl having 1-3 heteroatoms(N)(could be pyridine) with substituents which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-7 (88(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=DE19503827&ST=number&compact=false&DB=EPODOC DE19503827]===
[[Image:b7.jpg|thumb|center|500px]]
Q-R<sub>4</sub>
Q= above structure
R<sub>4</sub>= CR5R6R7 where R<sub>5</sub>= 1-4C alkyl, R<sub>6</sub>= H so no need of R<sub>7</sub>
R<sub>4</sub> matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>1</sub>= halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>2</sub>= alkylaryl substituted by halo matches with substituent at 4<sup>th</sup> position of pyrazole of generic structures
R<sub>3</sub>= substituted aryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-8 (86(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO9702252&ST=number&compact=false&DB=EPODOC WO9702252]===
[[Image:b5.jpg|thumb|center|500px]]
R<sub>1</sub>-R<sub>2</sub>= 1-4C alkyl, H matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>3</sub>= halogen matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>4</sub>= phenyl substituted with electron withdrawing group(halogens) matches with substituent at 4<sup>th</sup> position of pyrazole of generic structures
R<sub>5</sub>= substituted aryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-9 (41(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=20050811&NR=2005216490A&DB=EPODOC&locale=en_EP JP2005216490]===
[[Image:a16.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sup>1</sup>= lower alkyl which matches with R1(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>2</sup>= halogen which matches with R3(halogen) at 3<sup>rd </sup>position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>3</sup>= methoxyphenyl which indicates subtituent at 4<sup>th</sup> position of generic structure
*<nowiki></nowiki>R<sup>4</sup>= methoxy phenyl which matches with R<sup>2</sup>(substituted aryl)at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-10 (61(doc1))==
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=2004063166A1&KC=A1&FT=D&date=20040729&DB=EPODOC&locale=en_EP WO2004063166]===
[[Image:E.jpg|thumb|center|500px]]
*<nowiki></nowiki>Z1= C, Z2= N, Z3= N Which indicates pyrazole ring.
*<nowiki></nowiki>R1= Alkyl which matches with R<sup>1</sup>(alkyl) at the 1<sup>st</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>R32= halo which matches with R<sup>3</sup>(halogen) at the 3<sup>rd</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>R2(0-8Calkyl) so it may be <nowiki>’</nowiki>0<nowiki>’</nowiki>C alkyl implies it is simply a bond, bonded to a substituted phenyl ring which matches with R<sup>2</sup>(substituted aryl) at the 5<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>U is an aliphatic linker(linker means a bond, aliphatic means saturated. So aliphatic linker means saturated bond which implies a single bond) so it is a bond and X is a single bond linked to substituted aryl with halogens and cycloalkyl as substituents which matches with 4<sup>th</sup> position of pyrazole of the generic compound.
=Exact match structures but mentioned as optionally substituted at 4th position of pyrazole of generic structure=
==Structure-1 (84(doc2))==
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=9711952A1&KC=A1&FT=D&date=19970403&DB=EPODOC&locale=en_EP WO9711952]===
[[Image:k.jpg|thumb|right|500px]]
[[Image:a9.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sub>1</sub>-R<sub>4</sub>= 1-8C alkyl, haloalkyl, halo, phenyl(optionally substituted by halo, 1-4C alkyl, haloalkyl, alkoxy,)
*<nowiki></nowiki>R<sub>1</sub>= 1-8C alkyl which matches with R<sup>1</sup>(1-4C alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
*<nowiki></nowiki>R<sub>4</sub>= halo which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
*<nowiki></nowiki>R<sub>3</sub>= phenyl(optionally substituted by halo, alkoxy) which matches with substituent at 4<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sub>2</sub>= phenyl(optionally substituted) which matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of the generic structure
==Structure-2 (74(doc2))==
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=0130154A2&KC=A2&FT=D&date=20010503&DB=EPODOC&locale=en_EP WO0130154]===
[[Image:a7.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sup>1</sup>= (1-6C)alkyl which matches with R<sup>1</sup>(1-4C alkyl) at 1<sup>st</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>R<sup>2</sup>= halo which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>R<sup>3</sup>= phenyl optionally substituted with halo, 1-6C alkyl, 1-6C alkoxy which matches with substituent at 4<sup>th</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>R<sup>4</sup>= heterocyclyl containing 1 or 2N and optionally substituted which matches with R<sup>2</sup>(optionally substituted heteroaryl) at 5<sup>th</sup> position of the generic compound
==Structure-3 (39(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=20051006&NR=2005272306A&DB=EPODOC&locale=en_EP JP2005272306]===
[[Image:a15.jpg|thumb|center|500px]]
*<nowiki></nowiki>A= substituted heteroaryl which matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>1</sup>= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
*<nowiki></nowiki>R<sup>3</sup>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
*<nowiki></nowiki>R<sup>2</sup>= phenyl optionally substituted by Y(1-6C alkyl), 1-6C alkoxy and matches with subtituent at 4<sup>th</sup> position of pyrazole of generic structure
==Structure-4 (25(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=US2007066822&ST=number&compact=false&DB=EPODOC US2007066822]===
[[Image:b5.jpg|thumb|center|500px]]
R<sup>1</sup>-R<sup>2</sup>= H, -CH<sub>3</sub>, -C<sub>2</sub>H<sub>5</sub> which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sup>3</sup>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sup>4</sup>= 6-25C optionally substituted heteroaryl which resembles substituent at 4<sup>th</sup> position of pyrazole of the generic structure
R<sup>5</sup>= optionally substituted 6-25C heteroaryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-5 (23(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=US2007066854&ST=number&compact=false&DB=EPODOC US2007066854]===
Z<sup><nowiki>+</nowiki></sup>= pyrazolium (substituted at 1-5 R1-R5)
R<sub>1</sub>= -CH<sub>3</sub>, -C<sub>2</sub>H<sub>5</sub> which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>3</sub>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>4</sub>= 6-25C aryl optionally substituted by C<sub>2</sub>H<sub>5</sub>, OH which resembles substituent at 4<sup>th</sup> position of pyrazole of the generic structure
{|border="0" cellspacing="2" width="100%"
|R<sub>5</sub>= optionally substituted 6-25C heteroaryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
|
|-
|}
==Structure-6 (90(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=FR2723091&ST=number&compact=false&DB=EPODOC FR2723091]===
[[Image:b8.jpg|thumb|center|500px]]
X= halo, n= 2-4
Z<sub>1</sub>= N, Z<sub>2</sub>= CR<sub>5</sub>, Z<sub>4</sub>= CR<sub>7</sub>
R<sub>4</sub>-R<sub>7</sub>= alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure; halogen matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure; optionally substituted aryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure and matches with substituent at 4<sup>th</sup> position of pyrazole of generic structures
==Structure-7 (92(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO9600218&ST=number&compact=false&DB=EPODOC WO9600218]===
[[Image:b9.jpg|thumb|center|500px]]
Z= a bond,
R<sub>4</sub> is a pyrazole with substituents as 1-4C alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure; halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure; optionally substituted aryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure and matches with substituent at 4<sup>th</sup> position of pyrazole of generic structures
==Structure-8 (95(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A1&date=19950914&NR=9524403A1&DB=EPODOC&locale=en_EP WO9524403]===
[[Image:a11.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sub>1</sub>= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st </sup>position of pyrazole of the generic structure
*<nowiki></nowiki>R<sub>3</sub>= halo which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sub>4</sub>= heteroaryl optionally substituted indicating substituent at 4<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sub>5</sub>= optionally substituted heteroaryl which matches with R<sup>2</sup>(optionally substituted heteroaryl) at 5<sup>th</sup> position of pyrazole of the generic structure
==Structure-9 (98(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=19941220&NR=6345728A&DB=EPODOC&locale=en_EP JP6345728]===
[[Image:a12.jpg|thumb|center|500px]]
*<nowiki></nowiki>A= N, B= CR<sup>4</sup>
*<nowiki></nowiki>R<sup>5</sup>= 1-6C alkyl which matches with<sup> </sup>R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>3</sup>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>4</sup>= phenyl(optionally substituted by halo, CN, alkoxy)indicating substituent at 4<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>2</sup>= optionally substituted phenyl which matches with R<sup>2</sup>(optionally substituted aryl) at 5<sup>th</sup> position of pyrazole of the generic structure
==Structure-10 (34(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO2006084262&ST=number&compact=false&DB=EPODOC WO2006084262]===
It is pyrazolium with substituents
R<sub>1</sub>-R<sub>5</sub>= halogen matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure; -C<sub>2</sub>H<sub>5</sub> matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure; 6-20C substituted aryl with substituents as halogen, OH which resembles substituent at 4<sup>th</sup> position of pyrazole of the generic structure; R<sup>5</sup>= optionally substituted 6-20C heteroaryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
=Relevant structures with missing substituents=
==Structure-1==
===JP09204932===
[[Image:I.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sub>6</sub> is 1-3C alkyl which is matching with substituent R<sup>1</sup>(first position) of the generic structure
*<nowiki></nowiki>R<sub>7</sub> doesn<nowiki>’</nowiki>t exist.. so it is matching with the second position of the generic structure.
*<nowiki></nowiki>R8 is halogen so it is matching with the substituent R<sup>3</sup> (second position) of the generic structure
*<nowiki></nowiki>R<sub>11</sub> is phenyl<nowiki>’’’</nowiki>(substituents are missing)<nowiki>’’’</nowiki> which is matching with the fourth position of the generic structure
*<nowiki></nowiki>R<sub>10</sub> is phenyl which is matching with the substituent R<sup>2</sup>(fifth position) of the generic structure.
==Structure-2==
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=0018741A2&KC=A2&FT=D&date=20000406&DB=EPODOC&locale=en_EP WO0018741]===
[[Image:a8.jpg|thumb|center|500px]]
*<nowiki></nowiki>Q= pyrazolyl
*<nowiki></nowiki>In the above structure the substituted aryl bonded to Q(pyrazolyl) matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sub>1</sub>= haloalkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of the generic structure
*<nowiki></nowiki>R<sub>2</sub>= aryl optionally substituted with halo, lower alkoxy, CN which matches with substituent at 4<sup>th</sup> position of pyrazole of the generic structure.
*<nowiki></nowiki>But <nowiki>’’’</nowiki>R<sup>3</sup>(halogen) of pyrazole of generic structure is missing<nowiki>’’’</nowiki> in the above structure
==Structure-3==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=EP335381&ST=number&compact=false&DB=EPODOC EP335381]===
[[Image:b13.jpg|thumb|center|500px]]
D= NR12 , E<nowiki>’’</nowiki>= N, E<nowiki>’</nowiki>= CH, E= CH
R<sub>12</sub>= alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>7</sub>= halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>8</sub>= substituted benzene ring matches with substituent at 4<sup>th</sup> position(but missing substituents) of pyrazole of generic structures
Above pyrazole ring is attached to a substituted aryl matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-4==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=19940322&NR=5296484A&DB=EPODOC&locale=en_EP US5296484]===
[[Image:a13.jpg|thumb|center|500px]]
*<nowiki></nowiki>G= NR<sup>20</sup>, M= N
*<nowiki></nowiki>R<sup>11</sup>= halo, 1-4C alkyl, phenyl
*<nowiki></nowiki>This structure has substituted aryl at 5<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>At 4<sup>th</sup> position of pyrazole i.e.,aryl has no substituents compared to generic structure
*<nowiki></nowiki>One more substituent is missing on the pyrazole ring
==Structure-5==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A1&date=20060608&NR=2006122256A1&DB=EPODOC&locale=en_EP US2006122256]===
[[Image:a14.jpg|thumb|center|500px]]
*<nowiki></nowiki>AR<sup>2</sup>= pyrazol-4-yl optionally substituted by Q(halo, lower alkyl, phenyl)
*<nowiki></nowiki>Q substituted on AR<sup>2</sup>(pyrazole) indicates R<sup>3</sup>, R<sup>1</sup> and R<sup>5 </sup>of pyrazole of the generic structure
*<nowiki></nowiki>At 4<sup>th</sup> substituent of pyrazole one substituent is missing and one substituent is varying
==Structure-6==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=JP2004317641&ST=number&compact=false&DB=EPODOC JP2004317641]===
[[Image:a17.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sup>5</sup>= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>6</sup>= halogen which matches with R<sup>3</sup>(halogen)at 3<sup>rd</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>7</sup>= phenyl with no substituents. It represents substituent at 4<sup>th</sup> position of pyrazole of generic structure with substituents missing
*<nowiki></nowiki>R<sup>8</sup>= phenyl which matches with R<sup>2</sup>(aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-7==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=20041111&NR=2004317640A&DB=EPODOC&locale=en_EP&CC=JP&FT=D JP2004317640]===
[[Image:a18.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sup>5</sup>= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>6</sup>= halogen which matches with R<sup>3</sup>(halogen)at 3<sup>rd </sup>position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>7</sup>= phenyl with no substituents. It represents substituent at 4<sup>th</sup> position of pyrazole of generic structure with substituents missing
*<nowiki></nowiki>R<sup>8</sup>= phenyl which matches with R<sup>2</sup>(aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-8==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A1&date=20050623&NR=2005135045A1&DB=EPODOC&locale=en_EP&CC=US&FT=D US2005135045]===
[[Image:a19.jpg|thumb|center|500px]]
*<nowiki></nowiki>R= 1-4C alkyl, halogen , phenyl
*<nowiki></nowiki>R= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R= halogen which matches with R<sup>3</sup>(halogen)at 3<sup>rd</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R= phenyl with no substituents. It represents substituent at 4<sup>th</sup> position of pyrazole of generic structure with substituents missing
*<nowiki></nowiki>R= phenyl which matches with R<sup>2</sup>(aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-9==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO2006124776&ST=number&compact=false&DB=EPODOC WO2006124776]===
[[Image:b1.jpg|thumb|center|500px]]
R<sup>1</sup>= H, R<sup>2</sup>= halogen, R<sup>3</sup>= pyrazole with substituents, R<sup>5</sup>= H, R<sup>6</sup>= H
R<sup>3</sup> is a pyrazole ring with substituents as:
-CH<sub>3</sub> matches with R<sup>1</sup>(alkyl) of pyrazole of the generic structure
Above ring matches with subtituent at 4<sup>th</sup> position of pyrazole of the generic structure
R<sup>3</sup> and R<sup>2</sup> of pyrazole of generic structure are missing
==Structure-10==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO2007038363&ST=number&compact=false&DB=EPODOC WO2007038363]===
[[Image:b2.jpg|thumb|center|500px]]
R<sup>1</sup>= H, R<sup>2</sup>= halogen, R<sup>3</sup>= pyrazole with substituents, R<sup>5</sup>= H, R<sup>6</sup>= H
R<sup>3 </sup>is defined as 3-25C substituted heteroaryl having 1-3 heteroatoms of N(so can be pyrazole) in which the substituents are -CH<sub>3</sub>, halogen:
-CH<sub>3</sub> matches with R<sup>1</sup>(alkyl) of pyrazole of the generic structure and halogen matches with R<sup>3</sup>(halogen) of pyrazole of the generic structure
Above ring matches with subtituent at 4<sup>th</sup> position of pyrazole of the generic structure
R<sup>2</sup>(substituted aryl) of pyrazole of generic structure missing
==Structure-11==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=US2007100184&ST=number&compact=false&DB=EPODOC US2007100184]===
[[Image:b4.jpg|thumb|center|500px]]
R<sub>1</sub>= H
R<sub>2</sub>= -C<sub>2</sub>H<sub>5 </sub>which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>3</sub>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>4</sub>= optionally substituted 6-25C heteroaryl with 1-3 of O, N, S or with 1-3 of CH<sub>3</sub>, C<sub>2</sub>H<sub>5</sub>, 3-25, preferably 3-20C straight , branched or cyclic alkane or alkene optionally substituted with halogens which resembles substituent at 4<sup>th</sup> position of pyrazole of the generic structure but R<sup>7</sup> of pyrazole of generic structure is missing
{|border="0" cellspacing="2" width="100%"
|R<sub>5</sub>= optionally substituted 6-25C heteroaryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
|
|-
|}
==Structure-12==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=US2005020646&ST=number&compact=false&DB=EPODOC US2005020646]===
[[Image:b6.jpg|thumb|center|500px]]
R<sup>a</sup>= pyrazolyl optionally substituted with 1-3 substituents of R<sup>11</sup> or 1-4C alkyl
R<sup>11</sup> is defined as halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure; pyridyl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure; pyridyl matches with substituent at 4<sup>th</sup> position of pyrazole of generic structures but R<sup>7</sup> of generic structure is missing
==Structure-13==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=EP548680&ST=number&compact=false&DB=EPODOC EP548680]===
[[Image:b10.jpg|thumb|center|500px]]
X<sup>1</sup>= het
Het = pyrazolyl with substituents alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure; halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure; phenyl matches with substituent at 4<sup>th</sup> position(but missing substituents) of pyrazole of generic structures
Above aryl ring is a substituent on X<sup>1</sup> which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-14==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO03087062&ST=number&compact=false&DB=EPODOC WO2003087062]===
[[Image:b11.jpg|thumb|left|500px]]
[[Image:b11a.jpg|thumb|center|500px]]
G= above pyrazole
R<sub>3</sub>= alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>4</sub>= halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>5</sub>= phenyl matches with substituent at 4<sup>th</sup> position(but missing substituents) of pyrazole of generic structures
Above given aryl matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-15==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO0066562&ST=number&compact=false&DB=EPODOC WO200066562]===
[[Image:b12.jpg|thumb|center|500px]]
R<sub>4</sub>= alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>5</sub>= halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>6</sub>= optionally substituted aryl matches with substituent at 4<sup>th</sup> position(but missing substituents) of pyrazole of generic structures
Above given aryl matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
=Relevant structures with substituent variation=
==Structure-1==
===[http://v3.espacenet.com/publicationDetails/claims?CC=EP&NR=0080051A2&KC=A2&FT=D&date=19830601&DB=EPODOC&locale=en_EP EP0080051]===
[[Image:F.jpg|thumb|center|500px]]
*<nowiki></nowiki>In the above structure D is N & A,A<nowiki>’</nowiki>,D<nowiki>’</nowiki> are considered as carbons…so it is forming a pyrazole ring.
*<nowiki></nowiki>In the first position substituent R is 3-iodopropargyl, so it is matching with the substituent R1( first position) of the generic structure.
*<nowiki></nowiki>X is Cl, so it is matching with the substituent R<sup>3</sup> (third position) of the generic structure.
*<nowiki></nowiki>Y is 3-chloro-2-nitrophenyl which is matching with the ring of the fourth position of the generic structure but here <nowiki>’’’</nowiki>substituent variation<nowiki>’’’</nowiki> is there.
*<nowiki></nowiki>Z is phenyl, so it is matching with the substituent R<sup>2</sup> (fifth position) of the generic structure.
==Structure-2==
===[http://v3.espacenet.com/publicationDetails/claims?CC=US&NR=2005159470A1&KC=A1&FT=D&date=20050721&DB=EPODOC&locale=en_EP US2005159470]===
[[Image:D1.jpg|thumb|center|500px]]
*<nowiki></nowiki>First position: R<sub>3</sub> is alkyl, so it is matching with the substituent R<sup>1</sup> (first position) of the generic structure.
*<nowiki></nowiki>Second position: X is N, so it is matching with second position of the generic structure.
*<nowiki></nowiki>Third position: X is CR<sub>5</sub> , R<sub>5</sub> is halo so it is matching with the substituent R<sup>3</sup> (third position) of the generic structure.
*<nowiki></nowiki>Fourth position: In fourth position substituted aryl ring is present<nowiki>’’’</nowiki>(but it contains five substituents)<nowiki>’’’</nowiki>, is matching with fourth position of the generic structure.
*<nowiki></nowiki>Fifth position: X is CR<sub>5</sub>, R<sub>5</sub> is heteroaryl, so it is matching with substituent R<sup>2 </sup>(fifth position) of the generic structure.
=Other structures=
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=2007070607A2&KC=A2&FT=D&date=20070621&DB=EPODOC&locale=en_EP WO2007070607]===
[[Image:L1.jpg|thumb|center|500px]]
*R1-H,
*R2 is –C2H5 which matches with R1(alkyl) at 1st position of the generic structure
*R5 is halo which matches with R3(halogen) at 3rd position of pyrazole of the generic compound
*R4 is heteroaryl substituted by C2H5(one substituent is missing) matches with substituent at 4th position of the generic structure.
*R3 is substituted heteroaryl which is matching with the substituent R2(fifth position) of the generic structure
[[Image:xxx.jpg|thumb|center|800px]]
=Exact match structures=
==Structure-1 (12(doc1))==
===[http://v3.espacenet.com/publicationDetails/claims?CC=DE&NR=4124942A1&KC=A1&FT=D&date=19930128&DB=EPODOC&locale=en_EP DE4124942]===
[[Image:a5.jpg|thumb|center|400px]]
[[Image:a6.jpg|thumb|center|400px]]
*X<sub>1</sub> = A-B-C- C(sp2 carbon), X<sub>2</sub> = F-C-D-C(sp2 carbon), X<sub>3</sub> = R<sub>1</sub>-N<nowiki><</nowiki>, X<sub>4</sub> = N, X<sub>5</sub> = R<sub>2</sub>-C(sp2 carbon)
#X<sub>1</sub>: A =H , B = bond, C = (b) under B which is halo substituted phenylene which completely matches with 4<sup>th</sup> position substituent of the generic compound
#X<sub>2</sub>: D = (b) under B is a phenylene(implies a substituted aryl) and F-C- is a substituent on D. It is clear that this will match with R<sup>2 </sup>(substituent aryl) at the 5<sup>th</sup> position of pyrazole of the generic structure
#X<sub>3</sub>: R<sub>1</sub> = Q(alkyl) which matches with R<sup>1</sup>(alkyl) at the 1<sup>st</sup> position of pyrazole of the generic structure
#X<sub>4</sub>: N which matches with the 2<sup>nd</sup> position of pyrazole of the generic compound
#X<sub>5</sub>: R<sub>2</sub> = Cl, Br which matches with R<sup>3</sup>(halogen) at the 3<sub></sub><sub></sub><sup> rd </sup>position of pyrazole of the generic structure
==Structure-2 (9(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?CC=WO&NR=2007081019A1&KC=A1&FT=D&date=20070719&DB=EPODOC&locale=en_EP WO2007081019]===
[[Image:C1.jpg|thumb|right|700px]]
[[Image:C2.jpg|thumb|center|700px]]
In the above phenyl ring Q is pyrazole.
*<nowiki></nowiki>R<sup>2</sup>= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic compound.
*<nowiki></nowiki>R<sup>4</sup> is halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>4<sup>th</sup> position of above pyrazole is trihalo substituted aryl which matches with substituent at 4<sup>th</sup> position of pyrazole of generic compound .
*<nowiki></nowiki>5<sup>th</sup> position of pyrazole ring is above substituted aryl which matches with R<sup>2</sup>(substituted aryl) at the 5<sup>th</sup> position of pyrazole of generic compound.
==Structure-3 (125(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=19990518&NR=11130754A&DB=EPODOC&locale=en_EP&CC=JP&FT=D JP11130754]===
[[Image:H.jpg|thumb|center|500px]]
Consider left side ring the pyrazole ring
*<nowiki></nowiki>R<sub>1</sub> is 1-4C alkyl which is matching with substituent R<sup>1</sup>(first position) of the generic structure
*<nowiki></nowiki>X is Cl so it is matching with the substituent R<sup>3 </sup>(second position) of the generic structure
*<nowiki></nowiki>R<sub>2</sub> is phenyl substituted by halo, 1-4C alkyl, cyano which is matching with the fourth position of the generic structure
*<nowiki></nowiki>In the fifth position pyrazole(heteroaryl) is there…which is matching with the substituent R<sup>2</sup>(fifth position) of the generic structure.
==Structure-4 (109(doc2))==
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=2006078610A1&KC=A1&FT=D&date=20060727&DB=EPODOC&locale=en_EP WO2006078610]===
[[Image:J.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sub>2</sub> is 1-6C alkyl which is matching with substituent R<sup>1</sup>(first position) of the generic structure
*<nowiki></nowiki>R<sub>4</sub> is halo matching with the substituent R<sup>3</sup> (second position) of the generic structure
*<nowiki></nowiki>R<sub>3</sub> is heteroaryl or phenyl substituted by 1-8C alkyl, halo, CN, 1-6C alkoxy which is matching with the fourth position of the generic structure
*<nowiki></nowiki>In fifth position substituted aryl ring there, which is matching with the substituent R<sup>2</sup>(fifth position) of the generic structure.
==Structure-5 (128(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=19981027&NR=5827602A&DB=EPODOC&locale=en_EP&CC=US&FT=D US5827602]===
[[Image:a20.jpg|thumb|center|500px]]
*R<sub>1</sub>-R<sub>6</sub>=H, F, 1-4C alkyl, phenyl
*R<sub>2</sub>= 1-4C alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*R<sub>5</sub>= F which matches with R<sup>3</sup>(halo)at 1<sup>st</sup> position of pyrazole of the generic structure
*R<sub>4</sub>= phenyl substituted with an electron with drawing group matches with substituent at 4<sup>th</sup> position of pyrazole of generic structure
*R<sub>3</sub>= substituted aryl which matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of the generic structure
==Structure-6 (19(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=US2007100181&ST=number&compact=false&DB=EPODOC US 2007100181]===
[[Image:b3.jpg|thumb|center|500px]]
R<sub>1</sub>-R<sub>2</sub>= H, -C<sub>2</sub>H<sub>5 </sub>which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>3</sub>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>4</sub>= 6-25C heteroaryl having 1-3 heteroatoms(N)(could be pyridine) with substituents as halo, OH and alkyl which completely resembles substituent at 4<sup>th</sup> position of pyrazole of the generic structure
R<sub>5</sub>= 6-25C heteroaryl having 1-3 heteroatoms(N)(could be pyridine) with substituents which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-7 (88(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=DE19503827&ST=number&compact=false&DB=EPODOC DE19503827]===
[[Image:b7.jpg|thumb|center|500px]]
Q-R<sub>4</sub>
Q= above structure
R<sub>4</sub>= CR5R6R7 where R<sub>5</sub>= 1-4C alkyl, R<sub>6</sub>= H so no need of R<sub>7</sub>
R<sub>4</sub> matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>1</sub>= halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>2</sub>= alkylaryl substituted by halo matches with substituent at 4<sup>th</sup> position of pyrazole of generic structures
R<sub>3</sub>= substituted aryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-8 (86(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO9702252&ST=number&compact=false&DB=EPODOC WO9702252]===
[[Image:b5.jpg|thumb|center|500px]]
R<sub>1</sub>-R<sub>2</sub>= 1-4C alkyl, H matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>3</sub>= halogen matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>4</sub>= phenyl substituted with electron withdrawing group(halogens) matches with substituent at 4<sup>th</sup> position of pyrazole of generic structures
R<sub>5</sub>= substituted aryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-9 (41(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=20050811&NR=2005216490A&DB=EPODOC&locale=en_EP JP2005216490]===
[[Image:a16.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sup>1</sup>= lower alkyl which matches with R1(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>2</sup>= halogen which matches with R3(halogen) at 3<sup>rd </sup>position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>3</sup>= methoxyphenyl which indicates subtituent at 4<sup>th</sup> position of generic structure
*<nowiki></nowiki>R<sup>4</sup>= methoxy phenyl which matches with R<sup>2</sup>(substituted aryl)at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-10 (61(doc1))==
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=2004063166A1&KC=A1&FT=D&date=20040729&DB=EPODOC&locale=en_EP WO2004063166]===
[[Image:E.jpg|thumb|center|500px]]
*<nowiki></nowiki>Z1= C, Z2= N, Z3= N Which indicates pyrazole ring.
*<nowiki></nowiki>R1= Alkyl which matches with R<sup>1</sup>(alkyl) at the 1<sup>st</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>R32= halo which matches with R<sup>3</sup>(halogen) at the 3<sup>rd</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>R2(0-8Calkyl) so it may be <nowiki>’</nowiki>0<nowiki>’</nowiki>C alkyl implies it is simply a bond, bonded to a substituted phenyl ring which matches with R<sup>2</sup>(substituted aryl) at the 5<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>U is an aliphatic linker(linker means a bond, aliphatic means saturated. So aliphatic linker means saturated bond which implies a single bond) so it is a bond and X is a single bond linked to substituted aryl with halogens and cycloalkyl as substituents which matches with 4<sup>th</sup> position of pyrazole of the generic compound.
=Exact match structures but mentioned as optionally substituted at 4th position of pyrazole of generic structure=
==Structure-1 (84(doc2))==
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=9711952A1&KC=A1&FT=D&date=19970403&DB=EPODOC&locale=en_EP WO9711952]===
[[Image:k.jpg|thumb|right|500px]]
[[Image:a9.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sub>1</sub>-R<sub>4</sub>= 1-8C alkyl, haloalkyl, halo, phenyl(optionally substituted by halo, 1-4C alkyl, haloalkyl, alkoxy,)
*<nowiki></nowiki>R<sub>1</sub>= 1-8C alkyl which matches with R<sup>1</sup>(1-4C alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
*<nowiki></nowiki>R<sub>4</sub>= halo which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
*<nowiki></nowiki>R<sub>3</sub>= phenyl(optionally substituted by halo, alkoxy) which matches with substituent at 4<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sub>2</sub>= phenyl(optionally substituted) which matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of the generic structure
==Structure-2 (74(doc2))==
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=0130154A2&KC=A2&FT=D&date=20010503&DB=EPODOC&locale=en_EP WO0130154]===
[[Image:a7.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sup>1</sup>= (1-6C)alkyl which matches with R<sup>1</sup>(1-4C alkyl) at 1<sup>st</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>R<sup>2</sup>= halo which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>R<sup>3</sup>= phenyl optionally substituted with halo, 1-6C alkyl, 1-6C alkoxy which matches with substituent at 4<sup>th</sup> position of pyrazole of the generic compound
*<nowiki></nowiki>R<sup>4</sup>= heterocyclyl containing 1 or 2N and optionally substituted which matches with R<sup>2</sup>(optionally substituted heteroaryl) at 5<sup>th</sup> position of the generic compound
==Structure-3 (39(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=20051006&NR=2005272306A&DB=EPODOC&locale=en_EP JP2005272306]===
[[Image:a15.jpg|thumb|center|500px]]
*<nowiki></nowiki>A= substituted heteroaryl which matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>1</sup>= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
*<nowiki></nowiki>R<sup>3</sup>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
*<nowiki></nowiki>R<sup>2</sup>= phenyl optionally substituted by Y(1-6C alkyl), 1-6C alkoxy and matches with subtituent at 4<sup>th</sup> position of pyrazole of generic structure
==Structure-4 (25(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=US2007066822&ST=number&compact=false&DB=EPODOC US2007066822]===
[[Image:b5.jpg|thumb|center|500px]]
R<sup>1</sup>-R<sup>2</sup>= H, -CH<sub>3</sub>, -C<sub>2</sub>H<sub>5</sub> which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sup>3</sup>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sup>4</sup>= 6-25C optionally substituted heteroaryl which resembles substituent at 4<sup>th</sup> position of pyrazole of the generic structure
R<sup>5</sup>= optionally substituted 6-25C heteroaryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-5 (23(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=US2007066854&ST=number&compact=false&DB=EPODOC US2007066854]===
Z<sup><nowiki>+</nowiki></sup>= pyrazolium (substituted at 1-5 R1-R5)
R<sub>1</sub>= -CH<sub>3</sub>, -C<sub>2</sub>H<sub>5</sub> which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>3</sub>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>4</sub>= 6-25C aryl optionally substituted by C<sub>2</sub>H<sub>5</sub>, OH which resembles substituent at 4<sup>th</sup> position of pyrazole of the generic structure
{|border="0" cellspacing="2" width="100%"
|R<sub>5</sub>= optionally substituted 6-25C heteroaryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
|
|-
|}
==Structure-6 (90(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=FR2723091&ST=number&compact=false&DB=EPODOC FR2723091]===
[[Image:b8.jpg|thumb|center|500px]]
X= halo, n= 2-4
Z<sub>1</sub>= N, Z<sub>2</sub>= CR<sub>5</sub>, Z<sub>4</sub>= CR<sub>7</sub>
R<sub>4</sub>-R<sub>7</sub>= alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure; halogen matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure; optionally substituted aryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure and matches with substituent at 4<sup>th</sup> position of pyrazole of generic structures
==Structure-7 (92(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO9600218&ST=number&compact=false&DB=EPODOC WO9600218]===
[[Image:b9.jpg|thumb|center|500px]]
Z= a bond,
R<sub>4</sub> is a pyrazole with substituents as 1-4C alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure; halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure; optionally substituted aryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure and matches with substituent at 4<sup>th</sup> position of pyrazole of generic structures
==Structure-8 (95(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A1&date=19950914&NR=9524403A1&DB=EPODOC&locale=en_EP WO9524403]===
[[Image:a11.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sub>1</sub>= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st </sup>position of pyrazole of the generic structure
*<nowiki></nowiki>R<sub>3</sub>= halo which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sub>4</sub>= heteroaryl optionally substituted indicating substituent at 4<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sub>5</sub>= optionally substituted heteroaryl which matches with R<sup>2</sup>(optionally substituted heteroaryl) at 5<sup>th</sup> position of pyrazole of the generic structure
==Structure-9 (98(doc2))==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=19941220&NR=6345728A&DB=EPODOC&locale=en_EP JP6345728]===
[[Image:a12.jpg|thumb|center|500px]]
*<nowiki></nowiki>A= N, B= CR<sup>4</sup>
*<nowiki></nowiki>R<sup>5</sup>= 1-6C alkyl which matches with<sup> </sup>R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>3</sup>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>4</sup>= phenyl(optionally substituted by halo, CN, alkoxy)indicating substituent at 4<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>2</sup>= optionally substituted phenyl which matches with R<sup>2</sup>(optionally substituted aryl) at 5<sup>th</sup> position of pyrazole of the generic structure
==Structure-10 (34(doc2))==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO2006084262&ST=number&compact=false&DB=EPODOC WO2006084262]===
It is pyrazolium with substituents
R<sub>1</sub>-R<sub>5</sub>= halogen matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure; -C<sub>2</sub>H<sub>5</sub> matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure; 6-20C substituted aryl with substituents as halogen, OH which resembles substituent at 4<sup>th</sup> position of pyrazole of the generic structure; R<sup>5</sup>= optionally substituted 6-20C heteroaryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
=Relevant structures with missing substituents=
==Structure-1==
===JP09204932===
[[Image:I.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sub>6</sub> is 1-3C alkyl which is matching with substituent R<sup>1</sup>(first position) of the generic structure
*<nowiki></nowiki>R<sub>7</sub> doesn<nowiki>’</nowiki>t exist.. so it is matching with the second position of the generic structure.
*<nowiki></nowiki>R8 is halogen so it is matching with the substituent R<sup>3</sup> (second position) of the generic structure
*<nowiki></nowiki>R<sub>11</sub> is phenyl<nowiki>’’’</nowiki>(substituents are missing)<nowiki>’’’</nowiki> which is matching with the fourth position of the generic structure
*<nowiki></nowiki>R<sub>10</sub> is phenyl which is matching with the substituent R<sup>2</sup>(fifth position) of the generic structure.
==Structure-2==
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=0018741A2&KC=A2&FT=D&date=20000406&DB=EPODOC&locale=en_EP WO0018741]===
[[Image:a8.jpg|thumb|center|500px]]
*<nowiki></nowiki>Q= pyrazolyl
*<nowiki></nowiki>In the above structure the substituted aryl bonded to Q(pyrazolyl) matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sub>1</sub>= haloalkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of the generic structure
*<nowiki></nowiki>R<sub>2</sub>= aryl optionally substituted with halo, lower alkoxy, CN which matches with substituent at 4<sup>th</sup> position of pyrazole of the generic structure.
*<nowiki></nowiki>But <nowiki>’’’</nowiki>R<sup>3</sup>(halogen) of pyrazole of generic structure is missing<nowiki>’’’</nowiki> in the above structure
==Structure-3==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=EP335381&ST=number&compact=false&DB=EPODOC EP335381]===
[[Image:b13.jpg|thumb|center|500px]]
D= NR12 , E<nowiki>’’</nowiki>= N, E<nowiki>’</nowiki>= CH, E= CH
R<sub>12</sub>= alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>7</sub>= halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>8</sub>= substituted benzene ring matches with substituent at 4<sup>th</sup> position(but missing substituents) of pyrazole of generic structures
Above pyrazole ring is attached to a substituted aryl matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-4==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=19940322&NR=5296484A&DB=EPODOC&locale=en_EP US5296484]===
[[Image:a13.jpg|thumb|center|500px]]
*<nowiki></nowiki>G= NR<sup>20</sup>, M= N
*<nowiki></nowiki>R<sup>11</sup>= halo, 1-4C alkyl, phenyl
*<nowiki></nowiki>This structure has substituted aryl at 5<sup>th</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>At 4<sup>th</sup> position of pyrazole i.e.,aryl has no substituents compared to generic structure
*<nowiki></nowiki>One more substituent is missing on the pyrazole ring
==Structure-5==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A1&date=20060608&NR=2006122256A1&DB=EPODOC&locale=en_EP US2006122256]===
[[Image:a14.jpg|thumb|center|500px]]
*<nowiki></nowiki>AR<sup>2</sup>= pyrazol-4-yl optionally substituted by Q(halo, lower alkyl, phenyl)
*<nowiki></nowiki>Q substituted on AR<sup>2</sup>(pyrazole) indicates R<sup>3</sup>, R<sup>1</sup> and R<sup>5 </sup>of pyrazole of the generic structure
*<nowiki></nowiki>At 4<sup>th</sup> substituent of pyrazole one substituent is missing and one substituent is varying
==Structure-6==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=JP2004317641&ST=number&compact=false&DB=EPODOC JP2004317641]===
[[Image:a17.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sup>5</sup>= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>6</sup>= halogen which matches with R<sup>3</sup>(halogen)at 3<sup>rd</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>7</sup>= phenyl with no substituents. It represents substituent at 4<sup>th</sup> position of pyrazole of generic structure with substituents missing
*<nowiki></nowiki>R<sup>8</sup>= phenyl which matches with R<sup>2</sup>(aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-7==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A&date=20041111&NR=2004317640A&DB=EPODOC&locale=en_EP&CC=JP&FT=D JP2004317640]===
[[Image:a18.jpg|thumb|center|500px]]
*<nowiki></nowiki>R<sup>5</sup>= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>6</sup>= halogen which matches with R<sup>3</sup>(halogen)at 3<sup>rd </sup>position of pyrazole of the generic structure
*<nowiki></nowiki>R<sup>7</sup>= phenyl with no substituents. It represents substituent at 4<sup>th</sup> position of pyrazole of generic structure with substituents missing
*<nowiki></nowiki>R<sup>8</sup>= phenyl which matches with R<sup>2</sup>(aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-8==
===[http://v3.espacenet.com/publicationDetails/biblio?KC=A1&date=20050623&NR=2005135045A1&DB=EPODOC&locale=en_EP&CC=US&FT=D US2005135045]===
[[Image:a19.jpg|thumb|center|500px]]
*<nowiki></nowiki>R= 1-4C alkyl, halogen , phenyl
*<nowiki></nowiki>R= alkyl which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R= halogen which matches with R<sup>3</sup>(halogen)at 3<sup>rd</sup> position of pyrazole of the generic structure
*<nowiki></nowiki>R= phenyl with no substituents. It represents substituent at 4<sup>th</sup> position of pyrazole of generic structure with substituents missing
*<nowiki></nowiki>R= phenyl which matches with R<sup>2</sup>(aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-9==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO2006124776&ST=number&compact=false&DB=EPODOC WO2006124776]===
[[Image:b1.jpg|thumb|center|500px]]
R<sup>1</sup>= H, R<sup>2</sup>= halogen, R<sup>3</sup>= pyrazole with substituents, R<sup>5</sup>= H, R<sup>6</sup>= H
R<sup>3</sup> is a pyrazole ring with substituents as:
-CH<sub>3</sub> matches with R<sup>1</sup>(alkyl) of pyrazole of the generic structure
Above ring matches with subtituent at 4<sup>th</sup> position of pyrazole of the generic structure
R<sup>3</sup> and R<sup>2</sup> of pyrazole of generic structure are missing
==Structure-10==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO2007038363&ST=number&compact=false&DB=EPODOC WO2007038363]===
[[Image:b2.jpg|thumb|center|500px]]
R<sup>1</sup>= H, R<sup>2</sup>= halogen, R<sup>3</sup>= pyrazole with substituents, R<sup>5</sup>= H, R<sup>6</sup>= H
R<sup>3 </sup>is defined as 3-25C substituted heteroaryl having 1-3 heteroatoms of N(so can be pyrazole) in which the substituents are -CH<sub>3</sub>, halogen:
-CH<sub>3</sub> matches with R<sup>1</sup>(alkyl) of pyrazole of the generic structure and halogen matches with R<sup>3</sup>(halogen) of pyrazole of the generic structure
Above ring matches with subtituent at 4<sup>th</sup> position of pyrazole of the generic structure
R<sup>2</sup>(substituted aryl) of pyrazole of generic structure missing
==Structure-11==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=US2007100184&ST=number&compact=false&DB=EPODOC US2007100184]===
[[Image:b4.jpg|thumb|center|500px]]
R<sub>1</sub>= H
R<sub>2</sub>= -C<sub>2</sub>H<sub>5 </sub>which matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>3</sub>= halogen which matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>4</sub>= optionally substituted 6-25C heteroaryl with 1-3 of O, N, S or with 1-3 of CH<sub>3</sub>, C<sub>2</sub>H<sub>5</sub>, 3-25, preferably 3-20C straight , branched or cyclic alkane or alkene optionally substituted with halogens which resembles substituent at 4<sup>th</sup> position of pyrazole of the generic structure but R<sup>7</sup> of pyrazole of generic structure is missing
{|border="0" cellspacing="2" width="100%"
|R<sub>5</sub>= optionally substituted 6-25C heteroaryl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
|
|-
|}
==Structure-12==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=US2005020646&ST=number&compact=false&DB=EPODOC US2005020646]===
[[Image:b6.jpg|thumb|center|500px]]
R<sup>a</sup>= pyrazolyl optionally substituted with 1-3 substituents of R<sup>11</sup> or 1-4C alkyl
R<sup>11</sup> is defined as halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure; pyridyl which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure; pyridyl matches with substituent at 4<sup>th</sup> position of pyrazole of generic structures but R<sup>7</sup> of generic structure is missing
==Structure-13==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=EP548680&ST=number&compact=false&DB=EPODOC EP548680]===
[[Image:b10.jpg|thumb|center|500px]]
X<sup>1</sup>= het
Het = pyrazolyl with substituents alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure; halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure; phenyl matches with substituent at 4<sup>th</sup> position(but missing substituents) of pyrazole of generic structures
Above aryl ring is a substituent on X<sup>1</sup> which resembles R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-14==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO03087062&ST=number&compact=false&DB=EPODOC WO2003087062]===
[[Image:b11.jpg|thumb|left|500px]]
[[Image:b11a.jpg|thumb|center|500px]]
G= above pyrazole
R<sub>3</sub>= alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>4</sub>= halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>5</sub>= phenyl matches with substituent at 4<sup>th</sup> position(but missing substituents) of pyrazole of generic structures
Above given aryl matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
==Structure-15==
===[http://v3.espacenet.com/searchResults?locale=en_EP&NUM=WO0066562&ST=number&compact=false&DB=EPODOC WO200066562]===
[[Image:b12.jpg|thumb|center|500px]]
R<sub>4</sub>= alkyl matches with R<sup>1</sup>(alkyl) at 1<sup>st</sup> position of pyrazole of generic structure
R<sub>5</sub>= halo matches with R<sup>3</sup>(halogen) at 3<sup>rd</sup> position of pyrazole of generic structure
R<sub>6</sub>= optionally substituted aryl matches with substituent at 4<sup>th</sup> position(but missing substituents) of pyrazole of generic structures
Above given aryl matches with R<sup>2</sup>(substituted aryl) at 5<sup>th</sup> position of pyrazole of generic structure
=Relevant structures with substituent variation=
==Structure-1==
===[http://v3.espacenet.com/publicationDetails/claims?CC=EP&NR=0080051A2&KC=A2&FT=D&date=19830601&DB=EPODOC&locale=en_EP EP0080051]===
[[Image:F.jpg|thumb|center|500px]]
*<nowiki></nowiki>In the above structure D is N & A,A<nowiki>’</nowiki>,D<nowiki>’</nowiki> are considered as carbons…so it is forming a pyrazole ring.
*<nowiki></nowiki>In the first position substituent R is 3-iodopropargyl, so it is matching with the substituent R1( first position) of the generic structure.
*<nowiki></nowiki>X is Cl, so it is matching with the substituent R<sup>3</sup> (third position) of the generic structure.
*<nowiki></nowiki>Y is 3-chloro-2-nitrophenyl which is matching with the ring of the fourth position of the generic structure but here <nowiki>’’’</nowiki>substituent variation<nowiki>’’’</nowiki> is there.
*<nowiki></nowiki>Z is phenyl, so it is matching with the substituent R<sup>2</sup> (fifth position) of the generic structure.
==Structure-2==
===[http://v3.espacenet.com/publicationDetails/claims?CC=US&NR=2005159470A1&KC=A1&FT=D&date=20050721&DB=EPODOC&locale=en_EP US2005159470]===
[[Image:D1.jpg|thumb|center|500px]]
*<nowiki></nowiki>First position: R<sub>3</sub> is alkyl, so it is matching with the substituent R<sup>1</sup> (first position) of the generic structure.
*<nowiki></nowiki>Second position: X is N, so it is matching with second position of the generic structure.
*<nowiki></nowiki>Third position: X is CR<sub>5</sub> , R<sub>5</sub> is halo so it is matching with the substituent R<sup>3</sup> (third position) of the generic structure.
*<nowiki></nowiki>Fourth position: In fourth position substituted aryl ring is present<nowiki>’’’</nowiki>(but it contains five substituents)<nowiki>’’’</nowiki>, is matching with fourth position of the generic structure.
*<nowiki></nowiki>Fifth position: X is CR<sub>5</sub>, R<sub>5</sub> is heteroaryl, so it is matching with substituent R<sup>2 </sup>(fifth position) of the generic structure.
=Other structures=
===[http://v3.espacenet.com/publicationDetails/claims?CC=WO&NR=2007070607A2&KC=A2&FT=D&date=20070621&DB=EPODOC&locale=en_EP WO2007070607]===
[[Image:L1.jpg|thumb|center|500px]]
*R1-H,
*R2 is –C2H5 which matches with R1(alkyl) at 1st position of the generic structure
*R5 is halo which matches with R3(halogen) at 3rd position of pyrazole of the generic compound
*R4 is heteroaryl substituted by C2H5(one substituent is missing) matches with substituent at 4th position of the generic structure.
*R3 is substituted heteroaryl which is matching with the substituent R2(fifth position) of the generic structure
