Changes

===Executive '''Summary==='''<BR>One of the most talked about topic topics today is the Cloud Computing – the new phenomenon set to change the way we use computers forever. Cloud computing refers to the delivery of software and other technology services over the Internet by a service provider and has been widely acknowledged as a viable way to reduce capital expenditures and operational costs. Although many companies have embraced this technology, some are unwilling to switch from internally owned and managed IT systems to cloud computing technologies due to fears of security threats and loss of control over company systems and data.

'''===Cloud services provided worldwide are:'''<BR>===

'''===Companies providing cloud computing technology'''===

'''===Y-on-Y revenue from cloud services'''===

'''===Cloud services - revenue breakup'''===

'''===Pros and cons of cloud computing'''=== 

|align = "center" bgcolor = "#000000E6EED5"|'''Offerings'''|align = "center" bgcolor = "#000000E6EED5"|EC2 (Elastic Compute Cloud) plus S3 (Simple Storage Service)|align = "center" bgcolor = "#000000E6EED5"|Windows Azure|align = "center" bgcolor = "#E6EED5"|GoGrid|align = "center" bgcolor = "#000000E6EED5"|Google App Engine|align = "center" bgcolor = "#000000E6EED5"|Accelerator|align = "center" bgcolor = "#000000E6EED5"|GridLayer|align = "center" bgcolor = "#000000E6EED5"|The Hosting Cloud|align = "center" bgcolor = "#000000E6EED5"|Enterprise Cloud|align = "center" bgcolor = "#000000E6EED5"| FlexiScale

|align = "center" bgcolor = "#000000E6EED5"|'''Provider<nowiki>’</nowiki>s Data‐Storage System'''|bgcolor = "#000000E6EED5"|Amazon S3 Web service|bgcolor = "#000000E6EED5"|Azure Data Storage REST APIs, data storage functionality through three services BLOB, TABLE and QUEUE|bgcolor = "#E6EED5"|Storage is part of the server image; vendor plans to offer additional storage options|bgcolor = "#000000E6EED5"|Persistent storage with queries, sorting and transactions|bgcolor = "#000000E6EED5"|Sun Microsystems Sun Fire X4500 NAS storage|bgcolor = "#000000E6EED5"|Storage is built into the Grid; data is stored on multiple hard drives across multiple machines for redundancy|bgcolor = "#000000E6EED5"|Uses network‐attached storage devices|bgcolor = "#000000E6EED5"|Undisclosed|bgcolor = "#000000E6EED5"|Persistent storage based on a fully virtualized SAN/NAS back end

|align = "center" bgcolor = "#000000E6EED5"|'''Supported Languages'''|bgcolor = "#000000E6EED5"|Linux and Red Hat Enterprise|bgcolor = "#000000E6EED5"|.NET, Eclipse, Ruby, PHP, Java and Python|bgcolor = "#E6EED5"|Java, .NET, Perl, PHP, Python, Ruby on Rails and most shell‐scripting languages|bgcolor = "#000000E6EED5"|Python|bgcolor = "#000000E6EED5"|Java, PHP, Python and Ruby on Rails|bgcolor = "#000000E6EED5"|Grid nodes will run any software that runs on a normal dedicated compute|bgcolor = "#000000E6EED5"|.NET, Perl, PHP, Python and Ruby on Rails|bgcolor = "#000000E6EED5"|Undisclosed|bgcolor = "#000000E6EED5"|Linux and Microsoft Windows

|align = "center" bgcolor = "#000000E6EED5"|'''Scalability'''|bgcolor = "#000000E6EED5"|Limited to 20 virtual computer instances during beta period; additional instances are allowed|bgcolor = "#000000E6EED5"|No limits on scalability, additional VMs are allocated as processing load increases|bgcolor = "#E6EED5"|No limits on scalability|bgcolor = "#000000E6EED5"|Up to 5 million page views per month with preview release|bgcolor = "#000000E6EED5"|Contact vendor|bgcolor = "#000000E6EED5"|Up to 43 nodes. Bandwidth, RAM and CPU are changed on‐the‐fly. Process can be resized<br>(2 minutes per 1GB of data)|bgcolor = "#000000E6EED5"|Unlimited. Current users are pushing hundreds of millions of requests on single domains|bgcolor = "#000000E6EED5"|Undisclosed|bgcolor = "#000000E6EED5"|5 VDSes (Virtual Dedicated Servers) per account; more machines are available on request

|align = "center" bgcolor = "#000000E6EED5"|'''Virtualization Technology'''|bgcolor = "#000000E6EED5"|Xen|bgcolor = "#000000E6EED5"|Modified Hyper-V hypervisor|bgcolor = "#E6EED5"|Xen|bgcolor = "#000000E6EED5"|Undisclosed|bgcolor = "#000000E6EED5"|Solaris Zones|bgcolor = "#000000E6EED5"|Based on 3tera AppLogic|bgcolor = "#000000E6EED5"|Undisclosed|bgcolor = "#000000E6EED5"|Undisclosed|bgcolor = "#000000E6EED5"|Xen

|align = "center" bgcolor = "#000000E6EED5"|'''Load Balancing'''|bgcolor = "#000000E6EED5"|Undisclosed|bgcolor = "#000000E6EED5"|Yes, route traffic to active nodes only|bgcolor = "#E6EED5"|Yes; F5 Network BigIP load balancers.|bgcolor = "#000000E6EED5"|Yes|bgcolor = "#000000E6EED5"|Yes; F5 Network BigIP load balancers|bgcolor = "#000000E6EED5"|No. Customers can set up their own load balancing|bgcolor = "#000000E6EED5"|Yes; load‐balancing layer includes logic for multiple IP addresses for each customer site|bgcolor = "#000000E6EED5"|Undisclosed|bgcolor = "#000000E6EED5"|Yes; as optional add‐on

|align = "center" bgcolor = "#000000E6EED5"|'''Development Tools'''|bgcolor = "#000000E6EED5"|Command‐line tools for building AMIs|bgcolor = "#000000E6EED5"|Integration into Visual Studio, support for any .NET languages, complete command-line SDK tools|bgcolor = "#E6EED5"|No, not necessary; plans to release public API with the same control as the Web interface|bgcolor = "#000000E6EED5"|Python runtime environment,|bgcolor = "#000000E6EED5"|Sandbox accelerators, central development and deployment, version control, unit test site and staging site available as add‐ons|bgcolor = "#000000E6EED5"|AppLogic has a scriptable command‐line interface for provisioning and scaling applications|bgcolor = "#000000E6EED5"|None|bgcolor = "#000000E6EED5"|Undisclosed|bgcolor = "#000000E6EED5"|No

1. '''Access:'''::a. Application portfolio to identify core and non-core ==Cloud computing applicationsin different industry segments==::b. Map the scenarios relevant for cloud adoption::c. Identify business processes which are more suitable for cloud adoption::d. Evaluate the cloud vendors for strategic and tactical use scenarios===Pharmaceutical===

2. '''Validate:'''::a. Justify the cost benefits and * Historically, most large pharmaceutical firms have run fully integrated vertical business case::b. Perform pilots models, doing all they can in-house and proof of concepts choosing to identify functional gaps and assess user experienceselectively outsource where appropriate

3. '''Technology:'''::a. Changes * Firms now seek to be done on reduce the organizations policies time and procedures::b. Governance cost through sharing an integrated platform which is cheaper, less time consuming, and operations::c. Standardization across various cloud projectsmore supportive of a networked business model

4. '''Execute* Pharma companies exploring cloud computing have reported positive experiences through:'''* Easier implementation::a. Migration and Integration* More computational transparency::b. Co* A clear-existence and switchover planningcut IP policy[http://www.infosys.com/cloud-computing/white-papers/realizing-value-proposition.pdf Source: www.infosys.com]* Scalable invoicing

==Cloud '''Pfizer''' * Protein engineers and informaticians at Pfizer’s Biotherapeutics and Bioinnovation Center faced the challenging task of antibody docking that presented enormous computational roadblocks.* Each antibody model requires the respectable models of the protein’s three-dimensional structure to be generated on Rosetta++ platform which carries out refinement of antibody docking.* Refinement involves small local perturbations around the binding site followed by evaluation with Rosetta’s energy function – an iterative process using 200-nodes cluster that requires a massive amount of computing applications in .* An array of Rosetta workers are spun up on Amazon’s EC2. The S3 stores inputs and outputs, SimpleDB tracks job meta-data, and the Simple Queue Service glues it all together with message passing and the entire process is completed overnight which previously took months.* Consequently, the research staff is focusing more on results without pushing their projects on back-shelf. :[http://www.bio-itworld.com/issues/2009/may-jun/antibody-docking-EC2.html Source: bio-itworld] '''Eli Lilly''' * Eli Lilly is using cloud computing services to support scientists with on-demand processing power and storage.* The firm uses Amazon Web Services and other cloud services to provide high-performance computing, as needed, to hundreds of its scientists.* Eli Lilly foresees the possibility of using cloud services from a half dozen different vendors and need for an “orchestration layer” that sits between Eli Lilly and the various cloud services.* It would comprise algorithms that determine the best cloud service for a particular job based on lowest cost, highest performance, or other requirement. Such an approach would make it possible for Eli Lilly and other users to write to a single API rather than many, while optimizing service usage.* The firm is also exploring the potential to use cloud computing for external collaboration between Eli Lilly and outside researchers. :[http://www.undertheradarblog.com/blog/eli-lilly-the-future-of-pharmaceutical-research-and-cloud-computing/ Source: undertheradarblog] '''Johnson and Johnson''' * Johnson and Johnson is seeking to complement its high performance grid architecture with cloud computing, mainly in the area of drug discovery modeling applications, according to Rick Franckowiak, director for systems engineering at the Pharmaceutical Research & Development IT organization at Johnson & Johnson. * Require enhanced computing and storage capabilities and address spike-type processing demand. :[http://www.fiercebiotechit.com/story/j-j-pharma-r-d-looks-skyward/2009-06-12 Source:fiercebiotechit] '''Indigo BioSystems Inc.''' * Indigo BioSystems Inc., a privately held company offering data management and automated analysis solutions for life science researchers with a focus on the pharmaceutical industry.* It has deployed IBM's Compute on Demand cloud services to provide clients with a highly secure, scalable and compliant environment for data exchange.* IBM’s cloud services has been able to meet the clients’ requirements for a scalable and globally accessible platform for data exchange alongwith the security and regulatory compliances of the pharmaceutical industry segments==. :[http://www.prdomain.com/companies/I/IBM/newsreleases/200921167686.htm Source: prdomain]