Initially botox was marketed for its medical applications in treating various muscle-related conditions but later its marketing was broadened to include its cosmetic application—smoothing out frown lines between the eyebrows.<br>
===Y-o-Y sale Annual sales of botox Botox procedures===
[[Image:botox procedures time line.jpg|center|800px|thumb|[http://www.surgery.org/press/statistics.php Source: ASAPS]]]