[[Image:botox procedures time line.jpg|center|800px|thumb|[http://www.surgery.org/press/statistics.php Source: ASAPS]]]
Conclusions:-
* Safety of botox was proven through invasive muscular and neurological procedures very well till 1992.
* In 1992, a serendipitous discovery showed Botox effect on 'smoothing wrinkles'
* Expert Buzz started from 1992 onwards with publication of articles for use of Botox for wrinkle smoothing in leading journals (By Caruthers)
* Consumer Buzz started from 1992 with just 2 articles. But the big jump in Consumer buzz as measured by number of articles published in leading media is 35 in 1997.
* However, by 1997 more than 65,000 Botox procedures had been done. This indicates that the Expert Buzz played a big role in Botox adoption than the Consumer Buzz.
===Publication of botox articles for skin care===