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Alopecia - Hair Loss

386 bytes added, 04:27, 30 July 2006
/* Pathway associated with anti-androgen */
=== Pathway associated with anti-androgen ===
 
* Dihydrotestosterone
** Formed by peripheral conversion of testosterone by 5-alpha reductase
** Binds to androgen receptor on susceptible hair follicles
* Hormone-receptor complex activates genes responsible for gradual transformation of large terminal follicles to miniaturized (progressive diminution of hair shaft diameter and length in response to systemic androgens) follicles
 
[[Image:5-alpha-reductase inhibition.jpeg|center|500 px]]
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