Changes

Jump to: navigation, search

Alopecia - Hair Loss

78 bytes added, 14:46, 29 July 2006
/* Pathways associated with hair matrix cell activation */
* '''MAPK Pathway:''' Mitogen-activated protein kinase (MAPK) activation, increases keratinocyte turnover.
* '''NOTCH Pathway''': Notch-1 is expressed in ectodermal-derived cells of the follicle, in the inner cells of the embryonic placode and the follicle bulb, and in the suprabasal cells of the mature outer root sheath. Delta-1, one of the three ligands is only expressed during embryonic follicle development and is exclusive to the mesenchymal cells of the pre-papilla located beneath the follicle placode, and appears to promote and accelerate placode formation, while suppressing placode formation in surrounding cells. Other ligands, Serrate 1 and Serrate 2, are expressed in matrix cells destined to form the inner root sheath and hair shaft.
 
=== Pathways associated with Anti Androgen===
* '''TESTOSTERONE PATHWAY'''
 
 
[[Image:Slide1.GIF|thumb|center|700 px|Alopecia pathways]]
Anonymous user