Changes

Jump to: navigation, search

Alopecia - Hair Loss

1 byte added, 12:47, 29 July 2006
/* Pathways associated with hair matric cell */
* '''NOTCH Pathway''': Notch-1 is expressed in ectodermal-derived cells of the follicle, in the inner cells of the embryonic placode and the follicle bulb, and in the suprabasal cells of the mature outer root sheath. Delta-1, one of the three ligands is only expressed during embryonic follicle development and is exclusive to the mesenchymal cells of the pre-papilla located beneath the follicle placode, and appears to promote and accelerate placode formation, while suppressing placode formation in surrounding cells. Other ligands, Serrate 1 and Serrate 2, are expressed in matrix cells destined to form the inner root sheath and hair shaft.
[[Image:Slide1.GIF|thumb|center|700px700 px|Alopecia pathways]]
==== Players of Wnt inhibition Pathway ==== [[Image:wnt.jpg|thumb|right|250 200 px|Wnt inhibition]]
{| border="1" cellpadding="15", style="#008080"
!width="150" bgcolor=DodgerBlue|'''Patent no.'''
0
edits