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Alopecia - Hair Loss

8 bytes added, 11:24, 29 July 2006
/* Signaling Pathway and linkages */
[[Image:Slide1.GIF|thumb|center|700px|Alopecia pathways]]
==== Players of Wnt inhibition Pathway ==== [[Image:wnt.jpg|thumb|right|600px|Wnt inhibition]]
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!width="70" bgcolor=DodgerBlue|'''Patent no.'''
[[Image:coloury.jpg]]- '''Target sites and Details'''
==== Role of Pyrazole compounds in Wnt Pathway====
* '''Pyrazole''' (C3H4N2) refers both to the class of simple aromatic ring organic compounds of the heterocyclic series characterized by a 5-membered ring structure composed of three carbon atoms and two nitrogen atoms in adjacent positions and to the unsubstituted parent compound. Being so composed and having pharmacological effects on humans, they are classified as alkaloids although they are not known to occur in nature.
[[Image:pyrazole2.jpg|thumb|center|500px|Structurally related compounds]]
==== GSK3 inhibition by pyrazole compounds ====
[[Image:bold3.jpg]]
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==== Inhibition by amine derivatives ====
'''Patent Number''': US6989385