|}
== Sebum Production Inhibitor ==
Sebum Production Inhibitor is a substance that prevents the synthesis of sebum, mixture of lipid substances.
'''What causes hair loss?'''
* Sebum is a fatty acid substance secreted from sebaceous glands associated with hair follicles.
* Hair can get heavy sebum build-up and mixes with cholesterol to form a hardened plug around the bottom part of the hair bulb.
* Hardened plugs prevent cell respirations and eventually lead to hair loss.
* Bacteria will also attach to the hardened plug and this can also cause further cause problems with hair growth.
'''How does Sebum production inhibitor treat hair loss?'''
* The inhibitor prevents synthesis of sebum and slows down accumulation and mixing of sebum with cholesterol leading to hardened plugs.
* Reduction of sebum results in unclogged hair follicles/bulbs and allows oxygen and nutrients from reaching the hair follicle.
* Reduction in sebum also prevents vasoconstriction.
* Sum result of these effects of Sebum production inhibitor is prevention of hair loss.
* The inhibitor blocks the excessive sebum production produces greasy effect on hair and scalp and also responsible for thinning and loosing of hair.
=== Functions of Sebum Production Inhibitor ===
[[http://en.wikipedia.org/wiki/Image:HairFollicle.jpg Sebum Production Inhibitor]]
[[Image:Sebum1.jpg|thumb|center|500px|Functions of Sebum Production Inhibitor]]
=== IPMap for Sebum Production Inhibitor ===
{| border="1" cellpadding="3", style="#008080"
!width="100" bgcolor=DodgerBlue|'''Pat/Pub#'''
!width="75" bgcolor=DodgerBlue|'''Nature'''
!width="300" bgcolor=DodgerBlue|'''Composition'''
!width="300" bgcolor=DodgerBlue|'''Composition action'''
|- style="height:100px"
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050277699%22.PGNR.&OS=DN/20050277699&RS=DN/20050277699 US20050277699]
Unilever(2005)
|bgcolor=LightCyan|Natural extract and organic compound
|bgcolor=LightCyan|Polyamine (putrescine, spermine or spermidine) analogs and/or derivatives; DFMO; N-acetyl cysteines; neutralized salts of a non-hydroxy C2-C40 dicarboxylic acids, preferably malonate salts; and mixtures thereof.
|bgcolor=LightCyan|Decreasing sebum production and/or pore size
|- style="height:100px"
|bgcolor=LightCyan|[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220050244362%22.PGNR.&OS=DN/20050244362&RS=DN/20050244362 US20050244362]
KAO COPR.(2004)
|bgcolor=LightCyan|Natural extract and organic compound
|bgcolor=LightCyan|Avocado oil (Butyl esters of fatty acids)
|bgcolor=LightCyan|Reduce sebum of the hair and scalp
|- style="height:100px"
|bgcolor=LightCyan|[http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=4529587.PN.&OS=PN/4529587&RS=PN/4529587 US4529587]
Unilever(1982)
|bgcolor=LightCyan|organic compound
|bgcolor=LightCyan |Biotin antagonist or a salt thereof
|bgcolor=LightCyan|Decrease activity of the enzyme acetyl-SCoA-carboxylase and hence reduce lipid synthesis in sebaceous glands so that less sebum is produced
|}
== Composition nature matrix ==
