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Alopecia - Hair Loss

435 bytes added, 12:49, 25 July 2006
/* Minoxidil */
'''How does Minoxidal treat hair loss?'''
* Minoxidal is applied to the scalp topically, where it dilates blood vessels in the scalp and sustains the hair follicles for longer period of time.
* Scientists and researchers are not exactly sure of how Minoxidil leads is thought to this have a direct mitogenic effecton epidermal cells, as has been observed both in vitro in vivo. Though the mechanism of its action for causing cell proliferation is not very clear, minoxidil is thought to prevent intracellular calcium entry. Calcium normally enhances epidermal growth factors to inhibit hair growth, and Minoxidil by getting converted to minoxidil sulfate acts as a potassium channel agonist and enhances potassium ion permeability to prevent calcium ions from entering into cells.
* Minoxidil sulfate (MS) appears to be the active metabolite responsible for hair growth stimulation.
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