Changes

* Thus we have to target on We can only block the Oxygen oxygen atom at the Phosphorous group, marked on serine and threonine as a result which will in the red circles in the figure aboveturn stop Phosphorylation. * The two probable ways are (a) As oxygen is a Lewis acid with strong electron donating capacity, so usually a strong electron pair acceptor can easily bind to oxygen atom and preventing phosphorylationor (b) breaking of the -OH bond with the carbon atom.