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Alopecia - Hair Loss

903 bytes added, 19:18, 19 May 2006
* DHT causes gradual miniaturization of the follicle, which eventually results in hair loss.
'''How do anti-androgens prevent treat hair loss?'''
* Anti-androgens compete with DHT to bind to the androgen receptor.
* Upon binding of anti-androgen in place of DHT, follicle miniaturization is lowered and hair loss prevented.
* DHT accumulates in the hair follicles and roots, constricting the blood supply of oxygen and nutrients to the hair roots; which is also seen to possibly contribute towards hair loss.
'''How does Minoxidal prevent treat hair loss?'''
* Minoxidal is applied to the scalp topically, where it dilates blood vessels in the scalp and sustains the hair follicles for longer period of time.
* Scientists and researchers are not exactly sure of how Minoxidil leads to this effect.
== Hair matrix cell activator ==
* Hair matrix cell activator is a substance that acts at the matrix cells in the hair follicle preventing their degradation.
== Sebum Production Inhibitor ==
* Sebum, Production Inhibitor is a complex substance that prevents the synthesis of sebum, mixture of lipid substances, . '''What causes hair loss?'''* Sebum is a fatty acid substance secreted from sebaceous glands associated with hair follicles.* Hair can get heavy sebum build-up and mixes with cholesterol to form a hardened plug around the bottom part of the hair bulb.* Hardened plugs prevent cell respirations and eventually lead to hair loss.* Bacteria will also attach to the hardened plug and this can also cause further cause problems with hair growth. '''How does Sebum production inhibitor treat hair loss?'''* The inhibitor prevents synthesis of sebum and slows down accumulation and mixing of sebum with cholesterol leading to hardened plugs. * Reduction of sebum results in unclogged hair follicles/bulbs and allows oxygen and nutrients from reaching the hair follicle.* Reduction in sebum also prevents vasoconstriction.* Sum result of these effects of Sebum production inhibitor is prevention of hair loss.  
* The inhibitor blocks the excessive sebum production produces greasy effect on hair and scalp and also responsible for thinning and loosing of hair.
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