Changes
== Anti-androgens ==
* Anti-androgen is a substance that binds androgens are used in hormone therapy.* Anti-androgens are designed to affect the hormones made in the adrenal glands. They don't stop the hormones from being made, but they stop them from having an effect leading to androgen receptorshair loss.
'''What causes hair loss?'''
* Testosterone is reduced to its active metabolite, Dihydrotestosterone (DHT) by the enzyme 5 alpha reductase.
* DHT attaches to an androgen receptorsites at the hair follicle.
* DHT causes gradual miniaturization of the follicle, which eventually results in hair loss.
== Minoxidil ==
Minoxidil is a "potassium channel opener" that leads to vasodilation.The drug is available in two forms. Oral minoxidil is used to treat high blood pressure and the topical solution form is used to treat hair loss and baldness. '''What causes hair loss?'''* A thick network of tiny veins and arteries lines the outer wall of the follicle. Blood pumps through the bulb and hair via this network.* Minoxidil dilates DHT accumulates in the hair follicles and roots, constricting the blood vesselssupply of oxygen and nutrients to the hair roots; which is also called as “potassium channel opener”seen to possibly contribute towards hair loss. '''How does Minoxidal prevent hair loss?'''* Minoxidal is applied to the scalp topically, where it dilates blood vessels in the scalp and sustains the hair follicles for longer period of time.* Scientists and researchers are not exactly sure of how Minoxidil leads to this effect.
* Minoxidil sulfate (MS) appears to be the active metabolite responsible for hair growth stimulation.
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