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Alopecia - Hair Loss

75 bytes added, 17:49, 19 May 2006
[[Image:Active.jpg|thumb|center|500px|Active Assignees]]
== Anti-androgens == Anti-androgen is a substance that binds to androgen receptors. '''What causes hair loss?'''
* Testosterone is reduced to its active metabolite, Dihydrotestosterone (DHT) by the enzyme 5 alpha reductase.
* DHT attaches to an androgen receptor.
* DHT causes gradual miniaturization of the follicle, which eventually results in hair loss.
'''How do anti-androgens prevent hairloss?'''
* Anti-androgens compete with DHT to bind to the androgen receptor.
* Upon binding of anti-androgen in place of DHT, follicle miniaturization is lowered and hair loss prevented.
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