Changes
* Combination of Minoxidil + Anti-androgen (double action) composition for effective treatment of Male-Pattern Baldness
=== Functions of (Anti-androgen + Minoxidil) ===
[[Image:Doubleaction1.jpg|thumb|center|500px|Functions of (Anti-androgen + Minoxidil)]]
=== IP Map for (Anti-androgen + Minoxidil) ===
{| border="1" cellpadding="3"
!width="100"|'''Pat/Pub#'''
* It is from these cells that matrix cells are formed.
* Growth and differentiation of the matrix cells are under the influence of substances produced by cells of the dermal papilla.
[[Image:Hair matrix.jpg|thumb|center|500px|Functions of Hair matrix cell activator ]]
=== IP Map for Hair matrix cell activator ==={| border="1" cellpadding="2"!width="100"|'''Pat/Pub#'''!width="75"|'''Nature'''!width="300"|'''Composition''' !width="300"|'''Composition action'''|- style="height:100px" |US20020052498 SHISEIDO(1999)[[Imagehttp:Hair matrix1//appft1.jpguspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220020052498%22.PGNR.&OS=DN/20020052498&RS=DN/20020052498] |thumbOrganic compound|center(2-substituted oxyphenyl) alkanamide derivative and its salt|700pxMechanism of action has not been made clear, having excellent hair follicle activating action and regrowth promoting effect|- style="height:100px" |US20040071647L'OREAL(1998)[http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1&f=G&l=50&s1=%2220040071647%22.PGNR.&OS=DN/20040071647&RS=DN/20040071647] |Peptides|Metalloprotease (MMP-9) inhibitor (thiol or a hydroxamate) other than chelating calcium ions|Table listing different functions Reducing the expression of Hair MMPs (Metalloproteases) in the scalp - slow down or inhibit the degradation of the perifollicular matrix cell activator ]](extracellular matrix surround the hair follicle)
== Sebum Production Inhibitor ==
