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Alopecia - Hair Loss

95 bytes removed, 09:09, 28 April 2006
[[Image:Andogen1.jpg|thumb|center|500px|Functions of Anti-androgen]]
{| border="1" cellpadding="8"
!width="100"|Pat/Pub#
!width="75"|Nature
!width="300"|Composition
!width="300"|Composition action
|-
|US20060009430
BLOTECH (2004)
|Natural extracts
|Palmetto berry extract (fatty acids & sterols), Pumpkin seed extract (Vitamins-B, alpha-linolenic acid, amino acids and phytosterols), Quercetin (Flavonoids) and Beta-sitosterol (Rice bran, wheat germ, corn oils and soybeans)
|Fatty acids – Inhibit testosterone
Sterols - Mechanism of action unknown.
Quercetin results in cell growth cycle.
[[Image:Andogen2Beta-sitosterol reduce inflammation on scalp|-|US20060009427 WARNER LAMBERT(2004)|Organic compound|New class of 4-cycloalkoxy benzonitrile derivatives and salts|Acts as androgen receptor modulators and blocks formation of DHT.jpg|thumb-|centerUS20050085467WARNER LAMBERT(2004)|700pxOrganic compound|Table listing different functions New class of Anti6-sulfonamido-quinolin-2-one and 6-sulfonamido-2-oxo-chromene derivatives.|The compounds inhibit, or decrease, activation of androgen]]receptor by androgens.|-|US20050118282APHIOS Corp (2003)|Natural extracts|Supercritical fluid isolate of Saw Palmetto and Sperol (Serenoa repens berry) and their analogs or derivatives.|Modulates androgenic activity by inhibiting 5.alpha.-reductase activity.|-|US20060009429 Fundacion Pablo Cassara (2003)|Nucleotide|Pharmacologically active oligonucleotides (encompass both DNA and S-DNA bond)|Oligonucleotides inhibit androgen receptor (AR) expression at very low concentrations in skin and hair follicle|-|US20030007941 PFIZER INC (2001)|Organic compound|Thyromimetic compounds (structurally similar to thyronine) with finasteride, or cyproterone acetate |Activates thyroid hormone receptors in hair follicle which in turn promote elasticisation of follicle walls and hair follicle|-|US20030073616 N/A (1995)|Peptides/nucleic acid|Bradykinin antagonist (peptide of plasma origin from kininogen precursor-kallikrein)|Inhibit synthesis of bradykinin receptors or compounds by binding to B2 receptor|-|EP0279010 KAO Corp (1987)|Natural extracts|Walnut extract (leaves/pericarps) with an organic solvent|Blocks formation of DHT
== Minoxidil ==
* [http://www.biocarta.com/pathfiles/h_ghPathway.asp Pathways example]
* [http://www.cellsignal.com/category.asp?catalog_name=CellSignal&category_name=MAPK+Signaling Signaling Pathways]
 
{| border="1" cellpadding="8"
!width="100"|Pat/Pub#
!width="75"|Nature
!width="300"|Composition
!width="300"|Composition action
|-
|US20060009430
BLOTECH (2004)
|Natural extracts
|Palmetto berry extract (fatty acids & sterols), Pumpkin seed extract (Vitamins-B, alpha-linolenic acid, amino acids and phytosterols), Quercetin (Flavonoids) and Beta-sitosterol (Rice bran, wheat germ, corn oils and soybeans)
|Fatty acids – Inhibit testosterone
Sterols - Mechanism of action unknown.
Quercetin results in cell growth cycle.
 
Beta-sitosterol reduce inflammation on scalp
|-
|US20060009427
WARNER LAMBERT(2004)
|Organic compound
|New class of 4-cycloalkoxy benzonitrile derivatives and salts
|Acts as androgen receptor modulators and blocks formation of DHT.
|-
|US20050085467
WARNER LAMBERT(2004)
|Organic compound
|New class of 6-sulfonamido-quinolin-2-one and 6-sulfonamido-2-oxo-chromene derivatives.
|The compounds inhibit, or decrease, activation of androgen receptor by androgens.
|-
|US20050118282
APHIOS Corp (2003)
|Natural extracts
|Supercritical fluid isolate of Saw Palmetto and Sperol (Serenoa repens berry) and their analogs or derivatives.
|Modulates androgenic activity by inhibiting 5.alpha.-reductase activity.
|-
|US20060009429
Fundacion Pablo Cassara (2003)
|Nucleotide
|Pharmacologically active oligonucleotides (encompass both DNA and S-DNA bond)
|Oligonucleotides inhibit androgen receptor (AR) expression at very low concentrations in skin and hair follicle
|-
|US20030007941
PFIZER INC (2001)
|Organic compound
|Thyromimetic compounds (structurally similar to thyronine) with finasteride, or cyproterone acetate
|Activates thyroid hormone receptors in hair follicle which in turn promote elasticisation of follicle walls and hair follicle
|-
|US20030073616
N/A (1995)
|Peptides/nucleic acid
|Bradykinin antagonist (peptide of plasma origin from kininogen precursor-kallikrein)
|Inhibit synthesis of bradykinin receptors or compounds by binding to B2 receptor
|-
|EP0279010
KAO Corp (1987)
|Natural extracts
|Walnut extract (leaves/pericarps) with an organic solvent
|Blocks formation of DHT