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=Objective=
  
==''Patent Landscape Report''==
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* Perform a landscape search in the area of KTP LASER with application in skin care and cosmetics
 +
* Use PCS to derive insights and gain competitive perspective
 +
* Understand the value chain and recent M&A activities
  
{|class="wikitable"
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=Introduction=
|-
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! scope="col" bgcolor = "#EEECE1"|'''CP'''
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! scope="col" bgcolor = "#EEECE1"|'''Life Science'''
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! scope="col" bgcolor = "#EEECE1"|'''Food and Beverages'''
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! scope="col" bgcolor = "#EEECE1"|'''Auto'''
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! scope="col" bgcolor = "#EEECE1"|'''Technical'''
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! scope="col" bgcolor = "#EEECE1"|'''Energy'''
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">  [[Alopecia - Hair Loss]] <br> [http://www.youtube.com/watch?v=jAIoyKuKQ6o Video]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Inflammation and cardiovascular drugs]] <br> [http://www.youtube.com/watch?v=FVUFcz2dpIM Video]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Choline Bitartarate]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Hybrid Electric Vehicle Battery System]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[OLED - Organic Light Emitting Diode]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Wind Energy]]
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Non-wovens]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[RNAi Database sample wiki]] <br>[http://www.youtube.com/watch?v=nsZLUSPn3cg Video]
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|style="padding-left: 0.7em;"|<font color="#0000FF"> [[Pinene: An off flavor in mango juice]]<br>[http://www.youtube.com/watch?v=P4fI1rjPjSg Video]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Carbon Nanotubes (CNT)]]<br>[http://www.youtube.com/watch?v=HvZqBy8XvIE Video]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Pressure sensitive adhesives]] <br>[http://www.youtube.com/watch?v=plP3TzjYsiQ Video]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Ureteral Stent]]
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|style="padding-left: 3.7em;"|<font color="#0000FF">[[Bio-PET]]
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|style="padding-left: 0.7em;"|<font color="#0000FF"> [[Smart Drug Delivery Systems]] <br>[http://www.youtube.com/watch?v=vARe9eBFsq4 Video]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Pressure sensitive adhesives in packaging]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Silicone Hydrogel contact lens]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Golf Club Head Landscape]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Interferon For Treatment of Melanoma]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Antibody against TNF]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Template - Production Of Therapeutic Glycoproteins|Production of Therapeutic Glycoproteins]]
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==''Patent Search Report''==
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* The potassium titanyl phosphate (KTP) vascular laser has generally been used for the treatment of telangiectases and rosacea but has also recently been shown to be effective for the treatment of acne and wrinkles [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884837/ Ming H.Jih ]]
{|class="wikitable"
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* Superficial pigmented lesions have also been reported to be treated with KTP laser- 532 nm <nowiki>[</nowiki>[https://www.nature.com/articles/s41551-016-0008 Seok Hyun Yun]<nowiki>]</nowiki>
! scope="col" bgcolor = "#EEECE1"|'''PS-T'''
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* Irregular pigmentation and telangiectasia can be treated with intense pulsed light sources (IPL) and  532 nm potassium-titanyl-phosphate lasers (KTP). It has also been used to reverse the dermal and epidermal signs of photo- and chronological aging [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126803/ <nowiki>[</nowiki>Pinar Avci]<nowiki>]</nowiki>
! scope="col" bgcolor = "#EEECE1"|'''S-T'''
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|-
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[[Image:KTP_Laser_01.png|center|200px]]
|style="padding-left: 0.7em;"|<font color="#0000FF"> [http://www.dolcera.com/ipmapdemo/satellite_antenna/ipmap.html Satellite Antenna IPMap]
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<div style="text-align: center;">
|style="padding-left: 0.7em;"|<font color="#0000FF"> [[Invalidation Search on a patent in the semiconductors space|Invalidation Search]]
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<nowiki>[</nowiki>[http://www.centrelasersorbonne.com/Technical-Platform.html KTP VIRIDIS DERMA Multipulse (Quantel Médical)]<nowiki>]</nowiki>
|-
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</div>
|style="padding-left: 0.7em;"|<font color="#0000FF"> [http://www.dolcera.com/ipmapdemo/Invalidation_US4825448.htm Invalidation Claim Chart Sample]
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|style="padding-left: 0.7em;"|<font color="#0000FF"> [[Invalidation Search Sample in Chinese Language | Invalidation Search Sample (Chinese)]]
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[[Image:KTP_Laser_02.png|center|200px]]
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<div style="text-align: center;">
|}
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<nowiki>[</nowiki>[https://www.slideshare.net/AndromedSaglik/excel-v KTP 532 nm for Rosacea]<nowiki>]</nowiki>
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</div>
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 +
[[Image:KTP_Laser_03.png|center|200px]]
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<div style="text-align: center;">
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<nowiki>[</nowiki>[http://www.ipl-laser-machine.com/quality-1304287-ktp-laser-beauty-machine-for-skin-care KTP Laser Beauty- ROYAL-QL330]<nowiki>]</nowiki>
 +
</div>
 +
 
 +
=Search in PCS=
  
==''Market Research''==
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A search on PCS applications of KTP LASER in skin care was performed with the following search strategy:
{|class="wikitable"
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|-
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{|border="1" cellspacing="0" cellpadding="4" width="100%"
! scope="col" bgcolor = "#EEECE1"|'''MR-LS'''
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! scope="col" bgcolor = "#EEECE1"|'''MR-CP'''
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! scope="col" bgcolor = "#EEECE1"|'''MR-E'''
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! scope="col" bgcolor = "#EEECE1"|'''MR-FB'''
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! scope="col" bgcolor = "#EEECE1"|'''MR-T'''
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Strategic Insights:Heart Valve Replacement Market - India]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Botox - from Medical Procedure to Household Word]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[A market study on Hybrid vehicles and the concept of V2G]]
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|style="padding-left: 0.7em;"|<font color="#0000FF"> [[Premium Coffee Consumers Market Segmentation|Premium Coffee - Market Positioning]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[4G wireless technology developments]]
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Impact on Sales of a Drug going Off-Patent]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Dolcera's Poster on Industrial Biotechnology|Industrial biotechnology]]
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(text:ktp lasers OR text:potassium titanyl phosphate laser OR (laser AND text: potassium titanyl phosphate))
|style="padding-left: 0.7em;"|<font color="#0000FF">[[LTE]]
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Application of Conjoint Analysis for Total Knee Replacement Surgery Alternatives]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[OTC products for acne treatment]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Femtocells]]
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Cancer Vaccines - Clinical Trial Analysis]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Digestive Remedies Market in India and China]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[NFC Ecosystem]]
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Veterinary Vaccines Market Report]]* [[Rx to OTC Switch-Market Analysis]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Diabetes products and services]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Virtualization]]
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Ureteral Stent - Market Analysis]], Company Profile:[[Boston Scientific - Company Profile |Boston Scientific ]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Cloud Computing]]
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|-
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AND
|style="padding-left: 0.7em;"|<font color="#0000FF">[[Cardiac Pacemakers]]
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|
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(tac: skin care OR  tac: cosmetic treatment  OR tac: cosmetics OR tac: personal care OR tac: skin protection OR tac: acne vulgaris OR tac: wrinkle OR tac: skin rejuvenation OR scar OR tac: pigmentation OR tac: skin tags OR pimple OR tac: skin aging OR tac: hair removal OR text: rosacea)
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Drug Metabolism]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Toxicology]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Osteoporosis]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Oral Diabetes Drugs]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Ureteral Stent]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[China ICU Ventilator Market]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[OTC vs. Prescription Drugs]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Vaccines Market in Western Countries]], Company Profile:[http://dolcera.com/wiki/index.php?title=GlaxoSmithKline_profile GlaxoSmithKline]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Gastrointestinal Endoscopy -Landscape Report]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Transplant Diagnostics (HLA) Market Landscape]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Indian Pharma Industry - Distribution & Sales Force Structure]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Breast Reconstruction Market Landscape]]
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|style="padding-left: 0.7em;"|<font color="#0000FF">[[Lumpectomy and Mastectomy Trends]]
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|}
 
|}
  
==''Patent Prosecution''==
+
[[Image:KTP_Laser_Shape_newming1.png|center|800px]]
  
 +
[[Image:KTP_Laser_04.png|center|50px]]
  
{|class="wikitable"
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[[Image:KTP_Laser_newimg2.png|center|800px]]
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! scope="col" bgcolor = "#EEECE1"|'''Office Action'''
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">  [[Office Action Response]] <br>
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|}
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==''PCS''==
+
  
 +
=Top Assignee=
  
{|class="wikitable"
+
[[Image:KTP_Laser_06.png|800px]]
|-
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! scope="col" bgcolor = "#EEECE1"|'''PCS repots'''
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">  [[KTP LASER in skin care and cosmetics area]] <br>
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|-
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|style="padding-left: 0.7em;"|<font color="#0000FF">  [[Bone substitute-Dental application]] <br>
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|}
+
  
 +
* The top companies are big players in cosmetics and aesthetic devices from North America
 +
** Klox Tech- Quebec
 +
** Cynosure & OmniGuide - Massachusetts
 +
** Syneron & Neotract- California
 +
* Two major hospitals in US, that have also patented technologies in this space:
 +
** Community Health Systems
 +
** Pocono Health Systems
 +
* ThermoFischer Scientific patents come from its acquisition of ThermoLase Company
  
----
+
=Top Assignee Insights=
{| style="border:1px solid #AAA; background:#E9E9E9" align="center"
+
 
|-
+
[[Image:KTP_Laser_07.png|center|800px]]
! style="background:lightgrey" | Contact Dolcera
+
 
|-
+
* '''Johnson & Johnson''' has patents related to the treatment for acne , pigmentations, scars, and wrinkles
! style="background:lightgrey" | Samir Raiyani
+
* These patents are mainly using LASER therapy and don<nowiki>’</nowiki>t use any chemical agent alongside
|-
+
 
| '''Email''': [mailto:info@dolcera.com info@dolcera.com]
+
[[Image:KTP_Laser_08.png|center|800px]]
|-
+
 
| '''Phone''': +1-650-269-7952, +91-40-64550832
+
* Patents from '''Klox Technologies''' mentions various Biophotonic compositions and their use as therapy for photo-rejuvenation and wound healing
|}
+
 
 +
[[Image:KTP_Laser_09.png|center|800px]]
 +
 
 +
* All the '''Michael Locker Christian''' patents are co-assigned to '''Klox Technologies'''
 +
 
 +
=Bibliographic Analytics=
 +
 
 +
===Main CPC<nowiki>’</nowiki>s:===
 +
 
 +
[[Image:KTP_Laser_10.png|center|800px]]
 +
 
 +
* A61B-treatment/diagnosis with cosmetic procedures
 +
* A61N- Use of electrotherapy, magneto therapy, radiotherapy
 +
 
 +
===IP Activity:===
 +
 
 +
[[Image:KTP_Laser_11.png|center|800px]]
 +
 
 +
* IP activity started 20 years and saw a peak 10 years later
 +
* Very recently there is a decrease in the IP activity
 +
 
 +
===Geographical Distribution===
 +
 
 +
[[Image:KTP_Laser_12.png|center|800px]]
 +
 
 +
* Most of the patents in this technology are from US, Europe or China. There is hardly any activity from other geographies
 +
 
 +
=Technical Insights: CPC Distribution in Top Assignees:=
 +
 
 +
===CPC Distribution:===
 +
 
 +
[[Image:KTP_Laser_13.png|center|800px]]
 +
 
 +
* All the product based companies- Klox, Cynosure, OmniGuide, Syneron have heavy presence on the therapy based classes- A61B, A61N, A61K, A61Q and A61F
 +
* Community Health Systems and Pocono Health Systems have patents in therapy based classes of A61B, A61N, A61K and A61F
 +
* Technology development companies, e.g. 3M, have patented in upstream research like development of physical phenomena- G02, B23, B29 etc.
 +
 
 +
=Technical Insights: Concepts vs Top Assignees=
 +
 
 +
===Technology Concepts:===
 +
 
 +
[[Image:KTP_Laser_14.png|center|800px]]
 +
 
 +
* Cynosure patents disclose technologies related to Laser medicine, laser types and application in skin care, plastic surgery and ophthalmology
 +
* Klox has rather focused patent disclosures- Laser medicine in ophthalmology and skin care.
 +
* J&J patents are focused on skin care application and little disclosure on Laser technology itself.
 +
* Syneron, Thermo Fischer(ThermoLase), Community Health Systems and Pocono Health Systems patents have varied claims
 +
 
 +
=Value Chain Analysis=
 +
 
 +
[[Image:KTP_Laser_15.png|center|800px]]
 +
 
 +
=Latest M&A Activity in the Space=
 +
 
 +
* Klox Technologies and LEO Pharma establish a jointly owned company to further develop and commercialize Klox<nowiki>’</nowiki>s Bio-Photonic technology in dermatology including Kleresca® for acne and Kleresca® for skin rejuvenation <nowiki>[</nowiki>[http://www.leo-pharma.com/Home/LEO-Pharma/Media-centre/News/News-2017/Klox-Technologies-and-LEO-Pharma-set-up-company-for-BioPhotonic-in-dermatology.aspx Leo-][http://www.leo-pharma.com/Home/LEO-Pharma/Media-centre/News/News-2017/Klox-Technologies-and-LEO-Pharma-set-up-company-for-BioPhotonic-in-dermatology.aspx Pharma]<nowiki>]</nowiki>
 +
* Hologic, a developer and manufacturer of medical and diagnostic products, has recently purchased Cynosure. The acquisition is to address the demand for medical aesthetics market and more specifically non-surgical products that Cynosure makes <nowiki>[</nowiki>[http://www.reuters.com/article/us-cynosure-m-a-hologic-idUSKBN15T1OI Reuters]<nowiki>]</nowiki>
 +
* Botox maker Allergan Plc agreed to buy Cynosure<nowiki>’</nowiki>s rival Zeltiq Aesthetics Inc for about $2.48 billion
 +
* Apax Partners has acquired Syneron Candela in a deal valued at $400 Mn. Syneron Candela products include multi-wavelength picosecond laser systems for pigmented lesions, for female health and for removing tattoos, and alexandrite lasers for hair removal <nowiki>[</nowiki>[http://optics.org/news/8/4/2 Optics]<nowiki>]</nowiki>

Revision as of 03:53, 7 June 2017

Objective

  • Perform a landscape search in the area of KTP LASER with application in skin care and cosmetics
  • Use PCS to derive insights and gain competitive perspective
  • Understand the value chain and recent M&A activities

Introduction

  • The potassium titanyl phosphate (KTP) vascular laser has generally been used for the treatment of telangiectases and rosacea but has also recently been shown to be effective for the treatment of acne and wrinkles [Ming H.Jih ]
  • Superficial pigmented lesions have also been reported to be treated with KTP laser- 532 nm [Seok Hyun Yun]
  • Irregular pigmentation and telangiectasia can be treated with intense pulsed light sources (IPL) and 532 nm potassium-titanyl-phosphate lasers (KTP). It has also been used to reverse the dermal and epidermal signs of photo- and chronological aging [Pinar Avci]
KTP Laser 01.png

[KTP VIRIDIS DERMA Multipulse (Quantel Médical)]

KTP Laser 02.png

[KTP 532 nm for Rosacea]

KTP Laser 03.png

[KTP Laser Beauty- ROYAL-QL330]

Search in PCS

A search on PCS applications of KTP LASER in skin care was performed with the following search strategy:

(text:ktp lasers OR text:potassium titanyl phosphate laser OR (laser AND text: potassium titanyl phosphate))

AND

(tac: skin care OR tac: cosmetic treatment OR tac: cosmetics OR tac: personal care OR tac: skin protection OR tac: acne vulgaris OR tac: wrinkle OR tac: skin rejuvenation OR scar OR tac: pigmentation OR tac: skin tags OR pimple OR tac: skin aging OR tac: hair removal OR text: rosacea)

KTP Laser Shape newming1.png
KTP Laser 04.png
KTP Laser newimg2.png

Top Assignee

KTP Laser 06.png

  • The top companies are big players in cosmetics and aesthetic devices from North America
    • Klox Tech- Quebec
    • Cynosure & OmniGuide - Massachusetts
    • Syneron & Neotract- California
  • Two major hospitals in US, that have also patented technologies in this space:
    • Community Health Systems
    • Pocono Health Systems
  • ThermoFischer Scientific patents come from its acquisition of ThermoLase Company

Top Assignee Insights

KTP Laser 07.png
  • Johnson & Johnson has patents related to the treatment for acne , pigmentations, scars, and wrinkles
  • These patents are mainly using LASER therapy and dont use any chemical agent alongside
KTP Laser 08.png
  • Patents from Klox Technologies mentions various Biophotonic compositions and their use as therapy for photo-rejuvenation and wound healing
KTP Laser 09.png
  • All the Michael Locker Christian patents are co-assigned to Klox Technologies

Bibliographic Analytics

Main CPCs:

KTP Laser 10.png
  • A61B-treatment/diagnosis with cosmetic procedures
  • A61N- Use of electrotherapy, magneto therapy, radiotherapy

IP Activity:

KTP Laser 11.png
  • IP activity started 20 years and saw a peak 10 years later
  • Very recently there is a decrease in the IP activity

Geographical Distribution

KTP Laser 12.png
  • Most of the patents in this technology are from US, Europe or China. There is hardly any activity from other geographies

Technical Insights: CPC Distribution in Top Assignees:

CPC Distribution:

KTP Laser 13.png
  • All the product based companies- Klox, Cynosure, OmniGuide, Syneron have heavy presence on the therapy based classes- A61B, A61N, A61K, A61Q and A61F
  • Community Health Systems and Pocono Health Systems have patents in therapy based classes of A61B, A61N, A61K and A61F
  • Technology development companies, e.g. 3M, have patented in upstream research like development of physical phenomena- G02, B23, B29 etc.

Technical Insights: Concepts vs Top Assignees

Technology Concepts:

KTP Laser 14.png
  • Cynosure patents disclose technologies related to Laser medicine, laser types and application in skin care, plastic surgery and ophthalmology
  • Klox has rather focused patent disclosures- Laser medicine in ophthalmology and skin care.
  • J&J patents are focused on skin care application and little disclosure on Laser technology itself.
  • Syneron, Thermo Fischer(ThermoLase), Community Health Systems and Pocono Health Systems patents have varied claims

Value Chain Analysis

KTP Laser 15.png

Latest M&A Activity in the Space

  • Klox Technologies and LEO Pharma establish a jointly owned company to further develop and commercialize Kloxs Bio-Photonic technology in dermatology including Kleresca® for acne and Kleresca® for skin rejuvenation [Leo-Pharma]
  • Hologic, a developer and manufacturer of medical and diagnostic products, has recently purchased Cynosure. The acquisition is to address the demand for medical aesthetics market and more specifically non-surgical products that Cynosure makes [Reuters]
  • Botox maker Allergan Plc agreed to buy Cynosures rival Zeltiq Aesthetics Inc for about $2.48 billion
  • Apax Partners has acquired Syneron Candela in a deal valued at $400 Mn. Syneron Candela products include multi-wavelength picosecond laser systems for pigmented lesions, for female health and for removing tattoos, and alexandrite lasers for hair removal [Optics]